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  1. Hyperlipidemia is a vital etiology of acute pancreatitis (AP), 12 to 20% of which have a history of hyperlipidemia. Multiple organ failure is the major cause of the high mortality rate of AP. Liver injury has ...

    Authors: Jin-Ge Pan, Ru-Xue Qin, Xue-Ying Ma, Zi-Yu Han, Zhong-Hua Lu, Yun Sun and Wei-Li Yu
    Citation: Egyptian Liver Journal 2024 14:45
  2. In diseases characterized by fibrosis, hepatic stellate cells (HSCs) are mesenchymal cells that play an important role in liver fibrosis. circRNAs are involved in regulating hydatid exocyst formation through m...

    Authors: Baheti Kalifu, Yuan Meng, Zhi-Gang Ma, Chao Ma, Guang-Lei Tian, Jin-Guo Wang and Xiong Chen
    Citation: Egyptian Liver Journal 2024 14:44
  3. Nonalcoholic fatty liver disease (NAFLD) is a group of hepatic disorders ranging between simple form of accumulation of fat in hepatocytes (hepatic steatosis) and inflammation of liver internal tissues and inj...

    Authors: Ahmed Mohamed ElGhandour, Essam Mohammed Bayoumy, Moataz Mohammed Sayed, Moheb Sharaby Eskandaros, Abdelmomen Momen Mohamed Emam, Nahla Mohamed Teama, Manal Sabry Mohamed and Sonya Ahmed El-Gaaly
    Citation: Egyptian Liver Journal 2024 14:43
  4. Hepatic steatosis (HS) is a common and important histologic finding in patients with chronic hepatitis C virus (HCV) infection. However, little is known about this finding in HCV patients co-infected with huma...

    Authors: Aisha Elsharkawy, Shereen Abdel Alem, Saeed Moustafa, Shymaa Elnggar, Ahmed Cordie, Gamal Esmat and Ahmed Moustafa
    Citation: Egyptian Liver Journal 2024 14:42
  5. Hyponatremia portends a poor prognosis in decompensated cirrhosis and is an independent predictor of mortality. Multiple modalities have been evaluated in the management of hyponatremia, including albumin infu...

    Authors: Akash Roy, Suprabhat Giri, Sanchit Sharma, Surender Singh, Arka De, Prasun Jalal and Mahesh Goenka
    Citation: Egyptian Liver Journal 2024 14:41
  6. Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder that has been associated with an increased risk of cardiovascular diseases. Endothelial dysfunction, characterized by impaired flow-me...

    Authors: Nilesh Toke, Ajit Rathod, Pooja Phalak and Vikas Patel
    Citation: Egyptian Liver Journal 2024 14:40
  7. Acute liver failure (ALF) is a serious condition that refers to the development of synthetic function impairment after severe acute liver injury in an individual without pre-existing liver disease. Understandi...

    Authors: Nehad Sobhy Mansour, Behairy El-Sayed Behairy, Ahmad Mohamed Sira, Sally Waheed Elkhadry and Ola Ahmed Fouad
    Citation: Egyptian Liver Journal 2024 14:39
  8. Non-alcoholic fatty liver disease (NAFLD) is primarily perceived as a condition prevalent among obese individuals. Its pathogenesis is closely intertwined with metabolic syndrome components. However, the assoc...

    Authors: Meenu C. Nair, Lanord Stanley, Gisha Sivan and Janardanan Subramonia Kumar
    Citation: Egyptian Liver Journal 2024 14:38
  9. Hepatocellular carcinoma (HCC) is considered one of the most common cancers in the world and one of the principal causes of cancer-linked deaths. Therefore, identification of new biomarkers for diagnosis, espe...

    Authors: Eman Mohammed Helal, Sarah M. Shoeib and Shimaa Moustafa Mansour
    Citation: Egyptian Liver Journal 2024 14:37
  10. Hepatocellular carcinoma constitutes the most common primary hepatic cancer and remains a major medical burden in both developing and developed world. It ranks fifth in terms of global cases and second in term...

    Authors: Hany Samir Rasmy, Emad Ahmad Awad, Eslam Safwat Mohamed, Amal Samy Boshra, Shereen Abdel Monem Ibrahim and Amira Isaac
    Citation: Egyptian Liver Journal 2024 14:36
  11. HBV DNA assays have several limitations including being expensive and not widely available. Detection of HBsAg in serum has been the hallmark of HBV infection. However, previous studies regarding the associati...

    Authors: Ummi Maimunah, Puspa Wardhani, Citrawati Dyah Kencono Wungu, Anisa Firdausi Rahmanda, Andreas Agung Kurniawan and Andrio Palayukan
    Citation: Egyptian Liver Journal 2024 14:35
  12. Liver serves as a hub for key metabolic pathways such as folate cycle that provides one-carbon units for a network of metabolic reactions. Methylenetetrahydrofolate reductase (MTHFR) is a rate limiting enzyme ...

    Authors: Fatma Abozeid, Maysaa Zaki, Wafaa Nagah, Amany Ragab, Aya fathy, Dina Elhammady, Hayam Ghazy, Ahmed Yassen, Mohamed Serria, Omar Ammar, Maha Ragab and Manal Nomir
    Citation: Egyptian Liver Journal 2024 14:34
  13. Radiofrequency ablation (RFA) and microwave ablation (MWA) are widely accepted as the established treatment options for patients diagnosed with early-stage hepatocellular carcinoma (HCC) who are deemed unfit f...

    Authors: Mohamed Hassany, Ahmed Mostafa Mahboub, Wessam Mostafa, Hossam Debian, Hend Ibrahim Shousha and Magdy El-Serafy
    Citation: Egyptian Liver Journal 2024 14:33
  14. Mouth is the gateway to the total body wellness. Accordingly, oral microbiome influences overall health of an individual. Oral microbiome plays a key role in shaping up the host’s health profile. Obvious diffe...

    Authors: Maged Tharwat Elghannam, Moataz Hassan Hassanien, Yosry Abdelrahman Ameen, Emad Abdelwahab Turky, Gamal Mohammed ELattar, Ahmed Aly ELRay and Mohammed Darwish ELTalkawy
    Citation: Egyptian Liver Journal 2024 14:32
  15. Globally, MAFLD becomes in the top list of causes of liver disease. Its effect ranges from steatosis, metabolic steato-hepatitis to MAFLD-related cirrhosis and hepatocellular carcinoma. There is a growing evid...

    Authors: Eman Mahmoud Barakat, Iman Fawzy Montasser, Doaa Zakaria Zaky, Yasser Arafat Abdelrazik, Hoda Mohammed Farid, Ahmed El Dorry and Mohammed Kamal Shaker
    Citation: Egyptian Liver Journal 2024 14:30
  16. Osler-Weber-Rendu syndrome (OWRS) is an autosomal dominant disease with recurrent epistaxis, mucocutaneous telangiectasias, and arteriovenous malformations. Its clinical presentation ranges from simple skin le...

    Authors: ŞH Aktaş and S. Basat
    Citation: Egyptian Liver Journal 2024 14:29
  17. The human gut microbiota (GM) is a diverse ecosystem crucial for health, impacting physiological processes across the host's body. This review highlights the GM's involvement in Non-Alcoholic Fatty Liver Disea...

    Authors: Dinesh Mohan Swamikkannu, Santhosha Dasarapu, Rajendra Prasad Velivela Siva, Javali Nallam and Satvika Pabba
    Citation: Egyptian Liver Journal 2024 14:28
  18. Cyproheptadine is an easily available over-the-counter first-generation antihistaminic that is often used as an appetite stimulant. Although it is usually a safe drug, rare instances of drug-induced liver inju...

    Authors: Ayush Agarwal, Arpit Shastri, C. P. Ganesh, Malvika Shastri, Suvradeep Mitra, Debadrita Ray and Arka De
    Citation: Egyptian Liver Journal 2024 14:27
  19. Iron overload is a major problem in beta thalassemia patients due to repeated blood transfusions. The liver is the first organ to be loaded with iron. An accurate assessment of iron overload is necessary for m...

    Authors: Rohilla Seema, Chadha Kawaljeet Singh, Verma Anjali, Gill Paramjeet Singh, Yadav Alka and Singla Deepak
    Citation: Egyptian Liver Journal 2024 14:26
  20. Hepatocellular carcinoma is a major public health problem, as is considered the fastest growing cause of cancer-related death. Cannonball metastases as an initial finding in hepatocellular carcinoma are consid...

    Authors: Héctor Raúl Ibarra-Sifuentes, Gustavo Abraham Canales-Azcona, Jaqueline Isabel Gómez-Arredondo and Carlos Javier Rodríguez-Álvarez
    Citation: Egyptian Liver Journal 2024 14:25
  21. Eosinophilic ascites is non-common and challenging disease. This study aimed to describe the clinical presentation and treatment of eosinophilic ascites.

    Authors: Mohammed Ahmed Medhat, Mohamed O. Abdelmalek, Mohamed A. Mekky, Sherief Abd-Elsalam, Mohamed Ahmed Yehya Abdel-Malek, Sayed Hassan Ahmed, Yusuf S. Amry and Waleed Attia Hassan
    Citation: Egyptian Liver Journal 2024 14:24
  22. HBV infection is a significant concern in dialysis patients, influenced by various factors. This study aims to investigate the impact of serum uric acid levels on the immunogenicity of hepatitis Bvaccination i...

    Authors: Nasibe Golestani, Najmeh Shamspour, Jalal Azmandian, Habibeh Ahmadipour and Mahdi Karamipour zarei
    Citation: Egyptian Liver Journal 2024 14:23
  23. Obesity is a global health problem and has been increasing in Egypt over the last several decades. A national population screening program for hepatitis C included screening for obesity. Here we report the out...

    Authors: Gamal Esmat, Hala Zaid, Mohamed Hassany, Wael Abdel-Razek, Magdy El-Serafy, Wafaa El Akel, Aysam Salah, Ehab Kamal, Galal Elshishiney, Islam Ammar, Khaled Kabil, Mohamed AbdAllah, Ramy Saeed, Tarek Saad, Yasser Omar, Hany Dabbous…
    Citation: Egyptian Liver Journal 2024 14:22
  24. A prevalent liver condition called non-alcoholic fatty liver disease (NAFLD) may progress into non-alcoholic steatohepatitis (NASH) and cause life-threatening complications like cirrhosis and liver cancer. The...

    Authors: Pranali A. Jadhav, Asha B. Thomas, Rabindra K. Nanda and Sohan S. Chitlange
    Citation: Egyptian Liver Journal 2024 14:21
  25. Hepatic energy metabolism is intricately linked with the metabolic changes associated with HCV infection and hepatocellular carcinoma (HCC). This study investigated the potential of carnitine and acylcarnitine...

    Authors: Ashraf Abbass, Azza El Sheashaey, Ashraf El Fert, Manar Obada, Eman Abdelsameea, Mohammed Abdel-Samiee, Asmaa Ibrahim and Ashraf Khalil
    Citation: Egyptian Liver Journal 2024 14:19
  26. NS5A inhibitors are an important option for treating chronic HCV-GT4 patients. Retreatments after NS5A-based DAAs failure are limited. We aimed to determine the effectiveness and safety of SOF/VEL-containing r...

    Authors: Heba Omar, Mohammed Hamdy Abdel Maksoud, Ahmed A. Goma, Essam A. Hassan, Nancy Abdalla Atta, Mahmoud Khalil, Mohamed Soliman Hegazy, Samy Zaky and Gamal Esmat
    Citation: Egyptian Liver Journal 2024 14:18
  27. Biliary atresia (BA) is an obliterative cholangiopathy of infancy that results in cholestasis and liver fibrosis. This fibrosis is due to an imbalance in extracellular matrix (ECM) breakdown and deposition. Th...

    Authors: Alif Abdelhakim Allam, Mohammed Ahmed Khedr, Shimaa Saad Elkholy, Takwa Abd El Rahman Yassin and Ola Ahmed Fouad
    Citation: Egyptian Liver Journal 2024 14:17
  28. Alterations of hemostasis in patients with decompensated cirrhosis are complex. Accordingly, standard coagulation tests are not feasible to evaluate bleeding risk in these patients. The aim of this study was t...

    Authors: Mona A. Abu El-Makarem, Aml A. Mohammad, Ola A. Afifi, Nehal I. Abbas, Tarek A. Abd El-Zaher, Safaa M. Abdel Halim and Aliaa S. Abd El-Fattah
    Citation: Egyptian Liver Journal 2024 14:16
  29. Liver fibrosis is an irreversible liver destruction. Apigenin (API) has different pharmacological properties as anticancer, anti-inflammatory, and antioxidant; however, API hepatoprotective and therapeutic eff...

    Authors: Zaenah Zuhair Alamri
    Citation: Egyptian Liver Journal 2024 14:15
  30. Chronic hepatitis C virus (HCV) infection negatively impacts health-related quality of life (HRQL). We aimed to assess patient-reported outcomes (PROs) to evaluate the impact of treating chronic HCV with direc...

    Authors: Mohamed Elbadry, Mahmoud Badawi, Naglaa Youssef, Martin Duracinsky, Shereen A. Saleh, Anna Funk, Hagar Elessawy, Eva Rumpler, Khadiga Sayed, Anca Vasiliu, Yoann Madec, Arnaud Fontanet and Mohamed El-Kassas
    Citation: Egyptian Liver Journal 2024 14:14
  31. Chronic hepatitis B virus (HBV) infection poses a significant global health challenge, impacting millions of individuals and elevating the risk of morbidity and mortality. Antiviral therapies are the primary t...

    Authors: Syed Ayaz Kazmi, Abdul Rauf, Muhammad Zahid Latif, Beenish Shahid, Sundus Khawaja and Zeeshan Anjum
    Citation: Egyptian Liver Journal 2024 14:13
  32. Liver cirrhosis (LC) advances from an asymptomatic phase (compensated cirrhosis) to a symptomatic phase (decompensated cirrhosis). Up to 80% of patients with LC may experience minimal hepatic encephalopathy (M...

    Authors: Essam S. Bedewy, Abeer Elhadidi, Naglaa Abd El-Latif, Yousra T. El Zawawy and Amany N. Abbasy
    Citation: Egyptian Liver Journal 2024 14:12
  33. Esophageal varices are abnormally dilated submucosal veins of the esophagus which develop as a result of portal hypertension due to cirrhosis. Collagen type IV is upregulated with a 14-fold increase in cirrhos...

    Authors: Nasser Mohamed Abdalla, Fatma Mohamed Abd El Aziz, Akram Deghady, Mohamed Helmy Abaza and Walid Ismail Ellakany
    Citation: Egyptian Liver Journal 2024 14:11
  34. People all around the world are affected by primary liver cancers like hepatocellular carcinoma (HCC), which is usually associated with cirrhosis. Early HCC detection is crucial for better prognosis, but effec...

    Authors: Khaled Mahmoud Mohiedeen, Mona Moustafa Tahoon, Christina Samir Sadek Hanna and Mohamed Adel Abdel Aziz
    Citation: Egyptian Liver Journal 2024 14:10
  35. Pregnancy is not uncommon in patients with non-cirrhotic portal hypertension. Rupture of a splenic artery aneurysm remains a rare complication, associated with a very poor maternal–fetal prognosis. Our aim is ...

    Authors: Chantelli Iamblaudiot Razafindrazoto, Antsa Fihobiana Randrianiaina, Behoavy Mahafaly Ralaizanaka, Henintsoa Rakotoniaina, Nitah Harivony Randriamifidy, Anjaramalala Sitraka Rasolonjatovo, Andry Lalaina Rinà Rakotozafindrabe, Tovo Harimanana Rabenjanahary, Soloniaina Hélio Razafimahefa and Rado Manitrala Ramanampamonjy
    Citation: Egyptian Liver Journal 2024 14:9
  36. Non-alcoholic fatty liver disease (NAFLD) is a liver pathology. NAFLD’s prevalence is increasing in the world and because of the increase non-invasive methods are gaining importance in diagnosis. The Fibrosis ...

    Authors: Kutay Kirdok, Özge Yogurtcu, Tahir Buran and Elmas Kasap
    Citation: Egyptian Liver Journal 2024 14:8
  37. Pancreatic adenocarcinoma, recognized for its aggressive behavior and frequent late-stage diagnosis, imposes significant challenges in early detection and prognosis. This study aimed to evaluate the diagnostic...

    Authors: Ghada Salah, Manar Obada, Dina Sweed, Ibrahim Abdelkader Salama, Ashraf Khalil and Shimaa Abdelsattar
    Citation: Egyptian Liver Journal 2024 14:6
  38. Tetrahydrobiopterin deficiency in newborns with atypical hyperphenylalaninemia requires rapid and accurate diagnosis and the ability to distinguish it from the classical type to prevent early irreversible neur...

    Authors: Nadia Salama, Gamalte Elgedawy, Radwa Gamal, Osama Zaki, Ashraf Khalil and Manar Obada
    Citation: Egyptian Liver Journal 2024 14:5
  39. Hepatocellular carcinoma (HCC) is a highly aggressive and rapidly progressing form of cancer with a poor prognosis. Recent advances in the management of HCC focused on the novel immunotherapeutic modalities fo...

    Authors: Kashif Asghar, Shaarif Bashir, Muhammad Hassan, Asim Farooq, Muhammad Abu Bakar, Sundus Bilal, Maryam Hameed, Shafqat Mehmood and Asif Loya
    Citation: Egyptian Liver Journal 2024 14:4
  40. Hepatocellular carcinoma (HCC) is one of the most prevalent and fatal malignancies worldwide. Following an increase in reactive oxygen species (ROS), cancer cells enter an oxidative stress state. As a result, ...

    Authors: Khaled Mohamed Abdelwahab, Wesam Ahmed Ibrahim, Shereen Abou Bakr Saleh, Anas Abdelfattah Abdelaziz Elbarky and Ghada Abdelrahman Mohamed
    Citation: Egyptian Liver Journal 2024 14:3
  41. Hepatocellular carcinoma (HCC) is a common type of liver cancer, with a high mortality rate. Hepatocellular carcinoma is a type of liver cancer that can be effectively managed through early detection and accur...

    Authors: Tamer A. Addissouky, Ibrahim El Tantawy El Sayed, Majeed M. A. Ali, Yuliang Wang, Ayman El Baz, Ahmed A. Khalil and Naglaa Elarabany
    Citation: Egyptian Liver Journal 2024 14:2
  42. Acute gastrointestinal bleeding (GIB) is a significant medical condition that poses a considerable burden on healthcare systems worldwide. To effectively manage and improve outcomes for patients, it is essenti...

    Authors: Edite Sadiku, Liri Cuko, Ina Pasho, Orion Jucja, Stela Taci, Kliti Hoti and Bledar Kraja
    Citation: Egyptian Liver Journal 2024 14:1
  43. Pancreatic neuroendocrine tumors (PNET) account for less than 2% of all pancreatic tumors, while cystic PNETs account for only 10–18% of all resected PNETs. The most common site for metastasis is the liver. Fe...

    Authors: Maham Nasir Uddin, Muhammad Arsalan Khan and Abdaal Waseem Khan
    Citation: Egyptian Liver Journal 2023 13:69
  44. Colonic perforation usually presents with classical signs of peritonitis. However, isolated retroperitoneal colonic perforation can present with varied clinical signs and symptoms and pose diagnostic challenge...

    Authors: Kulbhushan Haldeniya, S. R. Krishna, Annagiri Raghavendra and Pawan Kumar Singh
    Citation: Egyptian Liver Journal 2023 13:68
  45. Malaria is an endemic mosquito-borne disease in sub-Saharan regions, including Cameroon. Due to the obligatory hepatic stage of its pathogenic agents, malaria can induce liver damage if not properly treated. H...

    Authors: Arnaud Fondjo Kouam, Noé Auguste Nseké Ngoumé, Armelle Gaelle Kwesseu Fepa, Zerubabel Wainfen, Eléonore Ngounou, Borris Rosnay Tietcheu Galani, Nembu Erastus Nembo, Pascal Dieudonné Djamen Chuisseu, Fréderic Nico Njayou and Paul Fewou Moundipa
    Citation: Egyptian Liver Journal 2023 13:67
  46. Liver cirrhosis (LC) has a significant impact in quality of life, and it is frequently linked to loss of a job, mood fluctuations, anxiety, low self-esteem, and despair. Recent LC treatment primarily focuses o...

    Authors: Syifa Mustika, Jefri Pratama Susanto and Cosmas Rinaldi Adithya Lesmana
    Citation: Egyptian Liver Journal 2023 13:66

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