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  1. Liver cirrhosis (LC) advances from an asymptomatic phase (compensated cirrhosis) to a symptomatic phase (decompensated cirrhosis). Up to 80% of patients with LC may experience minimal hepatic encephalopathy (M...

    Authors: Essam S. Bedewy, Abeer Elhadidi, Naglaa Abd El-Latif, Yousra T. El Zawawy and Amany N. Abbasy
    Citation: Egyptian Liver Journal 2024 14:12
  2. Esophageal varices are abnormally dilated submucosal veins of the esophagus which develop as a result of portal hypertension due to cirrhosis. Collagen type IV is upregulated with a 14-fold increase in cirrhos...

    Authors: Nasser Mohamed Abdalla, Fatma Mohamed Abd El Aziz, Akram Deghady, Mohamed Helmy Abaza and Walid Ismail Ellakany
    Citation: Egyptian Liver Journal 2024 14:11
  3. People all around the world are affected by primary liver cancers like hepatocellular carcinoma (HCC), which is usually associated with cirrhosis. Early HCC detection is crucial for better prognosis, but effec...

    Authors: Khaled Mahmoud Mohiedeen, Mona Moustafa Tahoon, Christina Samir Sadek Hanna and Mohamed Adel Abdel Aziz
    Citation: Egyptian Liver Journal 2024 14:10
  4. Pregnancy is not uncommon in patients with non-cirrhotic portal hypertension. Rupture of a splenic artery aneurysm remains a rare complication, associated with a very poor maternal–fetal prognosis. Our aim is ...

    Authors: Chantelli Iamblaudiot Razafindrazoto, Antsa Fihobiana Randrianiaina, Behoavy Mahafaly Ralaizanaka, Henintsoa Rakotoniaina, Nitah Harivony Randriamifidy, Anjaramalala Sitraka Rasolonjatovo, Andry Lalaina Rinà Rakotozafindrabe, Tovo Harimanana Rabenjanahary, Soloniaina Hélio Razafimahefa and Rado Manitrala Ramanampamonjy
    Citation: Egyptian Liver Journal 2024 14:9
  5. Non-alcoholic fatty liver disease (NAFLD) is a liver pathology. NAFLD’s prevalence is increasing in the world and because of the increase non-invasive methods are gaining importance in diagnosis. The Fibrosis ...

    Authors: Kutay Kirdok, Özge Yogurtcu, Tahir Buran and Elmas Kasap
    Citation: Egyptian Liver Journal 2024 14:8
  6. Pancreatic adenocarcinoma, recognized for its aggressive behavior and frequent late-stage diagnosis, imposes significant challenges in early detection and prognosis. This study aimed to evaluate the diagnostic...

    Authors: Ghada Salah, Manar Obada, Dina Sweed, Ibrahim Abdelkader Salama, Ashraf Khalil and Shimaa Abdelsattar
    Citation: Egyptian Liver Journal 2024 14:6
  7. Tetrahydrobiopterin deficiency in newborns with atypical hyperphenylalaninemia requires rapid and accurate diagnosis and the ability to distinguish it from the classical type to prevent early irreversible neur...

    Authors: Nadia Salama, Gamalte Elgedawy, Radwa Gamal, Osama Zaki, Ashraf Khalil and Manar Obada
    Citation: Egyptian Liver Journal 2024 14:5
  8. Hepatocellular carcinoma (HCC) is a highly aggressive and rapidly progressing form of cancer with a poor prognosis. Recent advances in the management of HCC focused on the novel immunotherapeutic modalities fo...

    Authors: Kashif Asghar, Shaarif Bashir, Muhammad Hassan, Asim Farooq, Muhammad Abu Bakar, Sundus Bilal, Maryam Hameed, Shafqat Mehmood and Asif Loya
    Citation: Egyptian Liver Journal 2024 14:4
  9. Hepatocellular carcinoma (HCC) is one of the most prevalent and fatal malignancies worldwide. Following an increase in reactive oxygen species (ROS), cancer cells enter an oxidative stress state. As a result, ...

    Authors: Khaled Mohamed Abdelwahab, Wesam Ahmed Ibrahim, Shereen Abou Bakr Saleh, Anas Abdelfattah Abdelaziz Elbarky and Ghada Abdelrahman Mohamed
    Citation: Egyptian Liver Journal 2024 14:3
  10. Hepatocellular carcinoma (HCC) is a common type of liver cancer, with a high mortality rate. Hepatocellular carcinoma is a type of liver cancer that can be effectively managed through early detection and accur...

    Authors: Tamer A. Addissouky, Ibrahim El Tantawy El Sayed, Majeed M. A. Ali, Yuliang Wang, Ayman El Baz, Ahmed A. Khalil and Naglaa Elarabany
    Citation: Egyptian Liver Journal 2024 14:2
  11. Acute gastrointestinal bleeding (GIB) is a significant medical condition that poses a considerable burden on healthcare systems worldwide. To effectively manage and improve outcomes for patients, it is essenti...

    Authors: Edite Sadiku, Liri Cuko, Ina Pasho, Orion Jucja, Stela Taci, Kliti Hoti and Bledar Kraja
    Citation: Egyptian Liver Journal 2024 14:1
  12. Pancreatic neuroendocrine tumors (PNET) account for less than 2% of all pancreatic tumors, while cystic PNETs account for only 10–18% of all resected PNETs. The most common site for metastasis is the liver. Fe...

    Authors: Maham Nasir Uddin, Muhammad Arsalan Khan and Abdaal Waseem Khan
    Citation: Egyptian Liver Journal 2023 13:69
  13. Colonic perforation usually presents with classical signs of peritonitis. However, isolated retroperitoneal colonic perforation can present with varied clinical signs and symptoms and pose diagnostic challenge...

    Authors: Kulbhushan Haldeniya, S. R. Krishna, Annagiri Raghavendra and Pawan Kumar Singh
    Citation: Egyptian Liver Journal 2023 13:68
  14. Malaria is an endemic mosquito-borne disease in sub-Saharan regions, including Cameroon. Due to the obligatory hepatic stage of its pathogenic agents, malaria can induce liver damage if not properly treated. H...

    Authors: Arnaud Fondjo Kouam, Noé Auguste Nseké Ngoumé, Armelle Gaelle Kwesseu Fepa, Zerubabel Wainfen, Eléonore Ngounou, Borris Rosnay Tietcheu Galani, Nembu Erastus Nembo, Pascal Dieudonné Djamen Chuisseu, Fréderic Nico Njayou and Paul Fewou Moundipa
    Citation: Egyptian Liver Journal 2023 13:67
  15. Liver cirrhosis (LC) has a significant impact in quality of life, and it is frequently linked to loss of a job, mood fluctuations, anxiety, low self-esteem, and despair. Recent LC treatment primarily focuses o...

    Authors: Syifa Mustika, Jefri Pratama Susanto and Cosmas Rinaldi Adithya Lesmana
    Citation: Egyptian Liver Journal 2023 13:66
  16. Background The most common cause of benign biliary stricture is bile duct injury after cholecystectomy. Benign biliary strictures are associated with a broad spectrum of signs and symptoms, ranging from subclinic...

    Authors: Kulbhushan Haldeniya, Niranjan Rajkumar Gandhi, Haritha Gorantla and Sindhura Bukka
    Citation: Egyptian Liver Journal 2023 13:65
  17. H. Pylori is one of the commonest infectious diseases worldwide. In recent years, PPI-based triple therapy has been described to be losing its efficacy against H. pylori due to high rates of antibiotic resistance...

    Authors: Sameh Mohamed Fakhry, Mohamed Abdel-Hameed Kandyl, Adel Ferig Hashish, Wafaa Kandeel, Ahmed Mostafa El-Shenawy, Hoda Samir El-Sayed, Mohamed Kamal Dewidar, Sameh Mohamed Badr and Nayra Shaker Mehanna
    Citation: Egyptian Liver Journal 2023 13:64
  18. NAFLD is a spectrum of disorders ranging from hepatic steatosis to nonalcoholic steatohepatitis (NASH), NASH related cirrhosis and hepatocellular carcinoma (HCC). There is sparse data on the prevalence CKD in ...

    Authors: Heba El Sayed Kasem, Ehab Ahmed Abdelatty, Ahmed Mohamed Mokhtar Yahia and Ezzat Mohamed Abdalla
    Citation: Egyptian Liver Journal 2023 13:63
  19. Alagille syndrome is a rare autosomal-dominant disorder, representing 10 to 15% of the causes of neonatal cholestasis with no gender predominance. The diagnosis is based on the association of liver, heart, eye...

    Authors: Oussama Kharmach, Mohamed Borahma and Fatima-Zohra Ajana
    Citation: Egyptian Liver Journal 2023 13:62
  20. Liver biopsy is crucial to know if the tumor is benign or malignant. This paper has reviewed the literature clinically shedding lights on the present biopsy procedure, requirements, and potential challenges. T...

    Authors: Serah Jessy Mathew, Anchal Nayak, Sagnika Dash and Sarada Prasad Dakua
    Citation: Egyptian Liver Journal 2023 13:61
  21. Endoscopic variceal ligation (EVL) is a crucial procedure for the primary and secondary prevention of variceal bleeding. The objective of this study was to evaluate the efficacy and tolerability of EVL in the ...

    Authors: Chantelli Iamblaudiot Razafindrazoto, Nitah Harivony Randriamifidy, Jolivet Auguste Rakotomalala, Sedera Radoniaina Rakotondrasoa, Behoavy Mahafaly Ralaizanaka, Henintsoa Rakotoniaina, Antsa Fihobiana Randrianiaina, Mialitiana Rakotomaharo, Domoina Harivonjy Hasina Laingonirina, Sonny Maherison, Anjaramalala Sitraka Rasolonjatovo, Andry Lalaina Rinà Rakotozafindrabe, Tovo Harimanana Rabenjanahary, Soloniaina Hélio Razafimahefa and Rado Manitrala Ramanampamonjy
    Citation: Egyptian Liver Journal 2023 13:60
  22. Brain-derived neurotrophic factor (BDNF) functions not only in the brain but also in peripheral tissues such as the liver. Genetic factors determine the development of alcohol dependence and somatic consequenc...

    Authors: Danil I. Peregud, Valeria Yu. Baronets, Anna S. Lobacheva, Alexandr S. Ivanov, Irina V. Garmash, Olga S. Arisheva, Zhanna D. Kobalava, Sergey V. Pirozhkov and Natalia N. Terebilina
    Citation: Egyptian Liver Journal 2023 13:59
  23. The natural history of pancreatic branch duct-type intraductal papillary mucinous neoplasms (BD-IPMNs) is still unknown. This retrospective study aims to determine the morphological changes of BD-IPMNs with at...

    Authors: Akira Imoto, Takeshi Ogura, Daisuke Masuda, Ken Narabayashi, Toshihiko Okada, Yosuke Abe, Toshihisa Takeuchi, Takuya Inoue, Kumi Ishida, Sadaharu Nouda, Kazuhide Higuchi and Usama M. Abdelaal
    Citation: Egyptian Liver Journal 2023 13:58
  24. Non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver disease in type-2 diabetics. The quality of life among those patients was not explored well. Hence, the present study aim...

    Authors: Usha Sree Puneem, Vanitha Rani Nagasubramanian, Vasudeva Murthy Sindgi, Subburaya Mudaliyar Rajendran Ramakrishnan and Ranakishor Pelluri
    Citation: Egyptian Liver Journal 2023 13:57
  25. Decompensated liver cirrhosis (DLC) is now known as a chronic inflammatory process, evidenced by elevated levels of circulatory pro-inflammatory cytokines and chemokines which in turn lead to the development o...

    Authors: Ayman F. El-Shayeb, Akram A. Degheidy, Sawsan El-Mallah, John Farid and Amany N. Abbasy
    Citation: Egyptian Liver Journal 2023 13:56
  26. Patients with chronic liver disease (CLD) as chronic hepatitis C (CHC) are at high risk of diabetes type 2 (T2D). Genetic factors are suggested to modulate diabetes development in cirrhotic patients. TCF7L2 ge...

    Authors: Mona Mahmoud Hassouna, Mohammed Sayed Moustafa, Mona Hamdy, Eman Abdelsameea, Mohamed Abbasy and Mary Naguib
    Citation: Egyptian Liver Journal 2023 13:54
  27. In malaria-endemic countries, repeated intake of artemisinin-based combination therapies (ACTs) is rampant and driven by drug resistance, improper usage, and easy accessibility. Stress effects and potential li...

    Authors: David Audu, Vinood B. Patel, Olufunmilayo A. Idowu, Fakilahyel M. Mshelbwala and Adewumi B. Idowu
    Citation: Egyptian Liver Journal 2023 13:53
  28. Contrast-enhanced magnetic resonance imaging (MRI) plays a crucial role in the diagnosis of hepatocellular carcinoma (HCC). This study aims to assess the performance of MRI features for evaluating hepatocellul...

    Authors: Aylin Altan Kus, Selim Keceoglu and Ali Ozer
    Citation: Egyptian Liver Journal 2023 13:52
  29. Hepatitis B virus (HBV) and hepatitis C virus (HCV) are amongst the most common causative agents of viral hepatitis with its severe complications, including liver cirrhosis, decompensation, and hepatocellular ...

    Authors: Aisha Elsharkawy, Reham Samir, Mohamed Abdallah, Mohamed Hassany and Mohamed El-Kassas
    Citation: Egyptian Liver Journal 2023 13:50
  30. Regression of fibrosis and improvement of portal hemodynamics after achievement of sustained viral response (SVR) in patients with chronic hepatitis C (HCV) is a subject of debate in different studies. Some st...

    Authors: Waleed Attia Hassan, Sherif I. Kamel, Ibrahim Abdel Naby Mahmoud, Nahed Makhlouf, Mahmoud Moubark and Sahar M. Hassany
    Citation: Egyptian Liver Journal 2023 13:49
  31. Tamiflu (Oseltamivir) and Adamine (Amantadine HCl) are antiviral drugs which are used for prevention and treatment for influenza. The present study was carried out to evaluate the effect of Tamiflu and Adamine...

    Authors: Nagla Zaky Ibrahim El-Alfy, Samia Mohamed Sakr, Mahmoud Fathy Mahmoud and Heba Ahmed Omar
    Citation: Egyptian Liver Journal 2023 13:46
  32. Dengue or breakbone fever is one of the most important causes of febrile illness in children residing in tropical and subtropical regions. This mosquito-borne viral disease is mediated by the bite of the infec...

    Authors: Rubaiyat Alam, Md. Rukunuzzaman and Khan Lamia Nahid
    Citation: Egyptian Liver Journal 2023 13:45
  33. Broad applications of nanoparticles have invoked the concerns about their impacts on living organisms. This study aimed to evaluate the possible changes that could take place in the liver of feral pigeons (Columb...

    Authors: Mehran Arabi and Hamid-Reza Naseri
    Citation: Egyptian Liver Journal 2023 13:44
  34. Elevated levels of serum liver transaminases are good indicators of liver cell damage, and elevated serum gamma-glutamyl transferase (GGT) level is a good indicator of both bile duct and hepatocellular damage....

    Authors: Epitagama Liyana Arachchige Navoda Navanjalee Dilhara, Kosgahagoda Durage Chandika Pushpakumara, Pathiranage Dias and Athapaththu Mudiyanselage Buddhika Priyadarshani
    Citation: Egyptian Liver Journal 2023 13:42
  35. This study’s purpose was to evaluate the response, safety and overall survival of trans-arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma with preserved hepatic function.

    Authors: Mohamed Houseni, Mahmoud Abdel Aziz Abdel Hady and Sameh Abokoura
    Citation: Egyptian Liver Journal 2023 13:41

    The Author Correction to this article has been published in Egyptian Liver Journal 2023 13:70

  36. The prognostic ability of albumin-bilirubin score (ALBI) to assess the hepatic dysfunction in patients with hepatocellular carcinoma (HCC) was previously studied. Its role in the staging of liver fibrosis post...

    Authors: Mohamed B. Hashem, Shereen Abdel Alem, Aisha Elsharkawy, Rabab Fouad, Gamal Esmat and Zeinab Abdellatif
    Citation: Egyptian Liver Journal 2023 13:40
  37. Terlipressin is a commonly used drug in cirrhotic patients with acute variceal bleed (AVB) due to its vasoconstrictor effects. Ischemic complications are uncommon adverse events associated with worse outcomes.

    Authors: Arpit Shastri, Sweta Rose, Nikhil Vojjala, Naveen Bhagat and Arka De
    Citation: Egyptian Liver Journal 2023 13:39
  38. Biliary atresia is associated with considerable morbidity, and it is the most frequent indication for pediatric liver transplantation. Hepatic portoentostomy (HPE), Kasai procedure, is used commonly as the fir...

    Authors: Samira A. Abdel-Aziz, Mohamed Taha, Mohamed Balabel, Osama Hegazy, Esam Salah, Mervat Soltan, Marowa A. Tahoon and Gihan A. Sobhy
    Citation: Egyptian Liver Journal 2023 13:38
  39. Currently, nonalcoholic liver disease (NAFLD) is the most predominant chronic liver disorder. NAFLD has been linked to hepatic and extrahepatic morbidities. We aimed to investigate the role of acoustic radiati...

    Authors: Mohamed Yosef El Hassafy, Abeer Shawky Elhadidi, Mona Mostafa Tahoon, Eman El-Dawi Hemimi and Sameh Aldesoky Lashen
    Citation: Egyptian Liver Journal 2023 13:37
  40. Laparoscopic cholecystectomy (LC) remains as the gold standard of surgical treatment for gallstone disease. Biliary duct injury (BDI) is an infrequent but serious complication of LC. Strasberg's critical view ...

    Authors: Jose Agustin Rodriguez Zamboni, Paloma Ruiz Diaz, Maria Elena Peña, Fernando Iglesia and Guillermo Pfaffen
    Citation: Egyptian Liver Journal 2023 13:36
  41. Chronic hepatitis C (HCV) and B viruses (HBV) represent the commonest global causes of liver cirrhosis. Other etiologies of non-viral cirrhosis such as autoimmune, metabolic, vascular, or biliary diseases are ...

    Authors: Haidi Karam-Allah Ramadan, Fathiya El-Raey, Samy Zaky, Asmaa Bakr, El-Zahraa M. Meghezel, Shamardan Ezzeldin S. Bazeed, Rehab Badawi, Sherief Abd-Elsalam, Mohamed Elbadry, Mahmoud Hagag and Mohamed Zakaria Abu Rahma
    Citation: Egyptian Liver Journal 2023 13:35
  42. Various laboratory parameters like C-reactive protein (CRP), Cortisol, and Von Willebrand factor antigen have been evaluated independently in foreseeing outcomes of cirrhotic patients. As these parameters lack...

    Authors: Sunil Kumar, Param Shah, Sourya Acharya, Anil Wanjari, Shilpa Bawankule, Sachin Agrawal, Charan Bagga, Dhruv Talwar and Mansi Patel
    Citation: Egyptian Liver Journal 2023 13:34
  43. The current study aimed to investigate the oxidative stress in rat liver with diabetes mellitus (DM) as well as the protective effects of N-acetylcysteine (NAC) on irisin expression.

    Authors: Mehmet Mustafa Erdogan, Mehmet Ali Erdogan, Suleyman Koc, Alper Yalcin, Ahmet Turk and Esra Akkus Yetkin
    Citation: Egyptian Liver Journal 2023 13:33

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