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Egyptian Liver Journal
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  1. Erdheim-Chester disease (ECD) is a rare histiocytic disorder recently recognized as a neoplasm due to the discovery of activating MAPK pathway mutations. Hepatic involvement by ECD is extremely rare.

    Authors: Ruchi Sharma, Mary S. Stone, Donald E. Macfarlane, Andrew M. Bellizzi and Gopala Koneru
    Citation: Egyptian Liver Journal 2023 13:4
    Content type: Case report Published on:

  2. NAFLD (non-alcoholic fatty liver disease) is increasing worldwide. Inflammation, fibrosis, and steatosis are the three components of NAFLD. Cardiac events are the most common cause of death in NAFLD. It is bel...

    Authors: Jijo Varghese, Krishnadas Devadas, Neeraj Vinayakumar, Nibin Nahaz, Atul Hareendran, Tharun Tom Oommen and Bony George
    Citation: Egyptian Liver Journal 2023 13:3
    Content type: Original Research Article Published on:

  3. Iatrogenic bile duct injuries are unusual but possibly associated with fatal complications with increased incidence since the introduction of laparoscopic cholecystectomy. Appropriate estimation of these injur...

    Authors: Mohamed Saied Abdelgawad, Mohamed Eid, Sameh Abokoura, Mohamed Amin Elmazaly and Rasha Abdelhafiz Aly
    Citation: Egyptian Liver Journal 2023 13:2
    Content type: Original Research Article Published on:

  4. Endoscopic papillary large balloon dilation (EPLBD) after sphincterotomy (EST) was introduced for the removal of large (≥ 10 mm) or multiple bile duct stones. This method combines the advantages of EST and EPL...

    Authors: Hossam Ibrahim Mohammed, Ali Saad Eldin Nada, Randa Mohamed Seddik and Ahmed Ragab ElGazara
    Citation: Egyptian Liver Journal 2023 13:1
    Content type: Original Research Article Published on:

  5. Hepatitis C virus, a member of Flaviviridae is a single-stranded positive-sense RNA virus infecting 62–79 million people around the globe. This blood-borne virus is one of the leading causes of liver diseases ...

    Authors: Fatima Butt, Muhammad Shahid, Muhammad Hassan, Farah Tawakkal, Iram Amin, Samia Afzal, Rashid Bhatti, Rabia Nawaz and Muhammad Idrees
    Citation: Egyptian Liver Journal 2022 12:71
    Content type: Review Published on:

  6. Dengue constitutes a public health problem in endemic regions. The clinical course can range from asymptomatic to severe expressions. Hemorrhagic manifestations are the most frequently reported complications; ...

    Authors: Carlos Eduardo Ruiz Gonzalez, Juan Daniel Criado Villamizar, Yuderleys Masías León, Diego Fernando García García and Katherine Tatiana Centeno Hurtado
    Citation: Egyptian Liver Journal 2022 12:70
    Content type: Case report Published on:

  8. Portal hypertension is considered as a major complication of liver cirrhosis. Endoscopy plays a main role in managing of gastrointestinal complications of portal hypertension. Endoscopists are at increased ris...

    Authors: Amr M. Elsayed, Yasser M. Fouad, Hatem A. Hassan, Taha M. Hassanin, Abbas M. Abbas and Alshymaa A. Hassnine
    Citation: Egyptian Liver Journal 2022 12:68
    Content type: Original Research Article Published on:

  9. Hepatitis C virus (HCV) may induce extrahepatic manifestations as acute or chronic renal dysfunction. The aim was to evaluate the diagnostic role of some biomarkers as cystatin C, cryoglobulins, rheumatoid fac...

    Authors: Nagwa Mohamed Assem, Amany Ibrahim Mohammed, Hamed Mohamed Abdel Barry, Ibrahim El Tantawy El Sayed and Ibrahim Elmadbouh
    Citation: Egyptian Liver Journal 2022 12:67
    Content type: Original Research Article Published on:

  11. Liver is a complex, highly vascular organ, where anatomical variations are the norm. This study aimed to analyze all the three hepatic vascular anatomical variations in a single study which would help us under...

    Authors: Panneerselvam Rajapriyan, Souradeep Dutta, Krishnan Nagarajan, Krishnaraj Ariharan and Vishnu Prasad Nelamangala Ramakrishnaiah
    Citation: Egyptian Liver Journal 2022 12:65
    Content type: Original Research Article Published on:

  12. Wilson disease (WD) is an inherited disorder of copper metabolism commonly involving the liver, cornea, and brain. Its incidence is increasing day by day worldwide. Early diagnosis and prompt treatment are the...

    Authors: Salahuddin Mahmud, Jahida Gulshan, Madhabi Baidya, Rafia Rashid, Farhana Tasneem, Ahmed Rashidul Hasan, Tanzila Farhana and Syed Shafi Ahmed
    Citation: Egyptian Liver Journal 2022 12:64
    Content type: Original Research Article Published on:

  13. Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases. It is shown that moderate to high physical activities can play a crucial role in improving this disease.

    Authors: Zahra Koohestani Sini, Mohammad Esmaeil Afzalpour, Mohsen Mohammadnia Ahmadi, Mohammad Ali Sardar, Homa Khaleghzadeh, Sattar Gorgani-Firuzjaee, Esedullah Akaras and Amin Azimkhani
    Citation: Egyptian Liver Journal 2022 12:63
    Content type: Original Research Article Published on:

  14. Hepatic encephalopathy (HE) is a main manifestation of acute decompensation in liver cirrhosis. Recently, systemic inflammation was proposed as a key mechanism in the development of acute kidney injury (AKI) i...

    Authors: Hossam Shahbah, Osman Mohamed Osman, Sadek Mostafa, Abdelgawad Saied Mohamed, Ahmed Alashkar, Mohamed Saad-Eldeen Radwan, Mohammed Salah Hussein, Alshimaa Alaboudy, Ahmed Eliwa, Ashraf Elbahrawy and Hafez Abdelhafeez
    Citation: Egyptian Liver Journal 2022 12:62
    Content type: Original Research Article Published on:

  15. The first direct-acting antiviral (DAA) medications were approved for the treatment of chronic hepatitis C virus (HCV) in 2011. Later, the appearance of novel DAAs had revolutionized the landscape of HCV treat...

    Authors: Mohamed Elbadry, Abdelmajeed M. Moussa, Mohamed Eltabbakh, Amira Al Balakosy, Mohammad Abdalgaber, Nermeen Abdeen, Reem Y. El Sheemy, Shimaa Afify and Mohamed El-Kassas
    Citation: Egyptian Liver Journal 2022 12:61
    Content type: Review Published on:

  16. Iron deficiency anemia is common among patients with chronic liver disease. Reticulocyte hemoglobin is a marker for iron availability in the bone marrow that is not affected by inflammation.

    Authors: Mariam Saad Nassim, Mona S. El Raziky, Kareem Baiomy and Mai Abd El Salam
    Citation: Egyptian Liver Journal 2022 12:60
    Content type: Original Research Article Published on:

  17. Neutrophil extracellular traps (NETs) have been shown to play an important role in inflammatory and thrombotic processes. Investigating the presence of NETs in liver cirrhosis to detect any contribution to occ...

    Authors: Enaam Ali ElSayed Al Mowafy and Salma AbdelGhany Shawkat
    Citation: Egyptian Liver Journal 2022 12:59
    Content type: Original Research Article Published on:

  18. Hepatocellular carcinoma (HCC) is one of the main cancers in the world with a high mortality rate. The molecular mechanisms of HCC are poorly understood. Long non-coding RNAs (lncRNAs) have a role in HCC patho...

    Authors: Ahmed Ramadan, Ashraf Omar Abdelaziz, Dina Sabry, Shaimaa Abd El tawab Fathi, Mohamed Mahmoud Nabeel, Hend Ibrahim Shousha, Tamer Mahmoud Elbaz, Rania mohamed Lithy and Hoda Ramadan Ryed
    Citation: Egyptian Liver Journal 2022 12:58
    Content type: Original Research Article Published on:

  19. Non-pharmacological exposure or pharmacological drug-induced hepatic injury is the most common cause of hepatotoxicity. This study was conducted to evaluate the effect of Moringa oleifera leaf extract against bis...

    Authors: Yasmin A. Abd-Elnaby, Ibrahim E. ElSayed, Mabrouk A. AbdEldaim, Eman A. Badr, Mona M. Abdelhafez and Ibrahim Elmadbouh
    Citation: Egyptian Liver Journal 2022 12:57
    Content type: Original Research Article Published on:

  20. Genetic variants of Patatin-like phospholipase domain-containing protein 3 (PNPLA3) and transmembrane 6 superfamily member 2 (TM6SF2) genes have been reported with the development of hepatocellular carcinoma (...

    Authors: Samar Samir Youssef, Eman Abd El Razek Abbas, Asmaa M. Elfiky, Sameh Seif, Mohamed Mahmoud Nabeel, Hend Ibrahim Shousha and Ashraf Omar Abdelaziz
    Citation: Egyptian Liver Journal 2022 12:56
    Content type: Original Research Article Published on:

  21. Telmisartan is a non-peptide angiotensin II receptor antagonist which acts by ACE/AngII/AT1 axis blockade (ARB). In the last years increasing evidence of its metabolic benefits pointed out this drug as the mos...

    Authors: Luciana Mendes Araújo Borém, Daniela Fernanda Freitas, Amanda Souto Machado, Alanna Fernandes Paraíso, Bruna Viana Caldas, João Felício Rodrigues Neto, Juliana Pinto Lima, André Luiz Sena Guimarães, Alfredo Maurício Batista de Paula and Sérgio Henrique Sousa Santos
    Citation: Egyptian Liver Journal 2022 12:55
    Content type: Original Research Article Published on:

  22. Recent studies suggested association between hepatitis C virus (HCV) infection and cardiovascular disorders, including carotid atherosclerosis with evidence of an effect of HCV clearance on carotid atheroscler...

    Authors: Marwa Ahmed Mohamed, Essam M. Bayoumy, Mostafa Mohamed Swailam and Ahmed Samir Allam
    Citation: Egyptian Liver Journal 2022 12:54
    Content type: Original Research Article Published on:

  23. Despite the effectiveness of new therapies and awareness campaigns, the number of seropositive patients is increasing every year. Recently, other causes of death, not directly related to HIV, have emerged, suc...

    Authors: Francesco Cammarata, Laura Benuzzi, Michele Crespi, Albert Troci, Luca Pennacchi, Monica Schiavini and Diego Foschi
    Citation: Egyptian Liver Journal 2022 12:53
    Content type: Original Research Article Published on:

  24. Hepatitis C virus (HCV) infection is the global epidemic of this century, affecting almost 100 million people, and it is now the leading cause of liver-related mortality and liver transplantation. Interferon (...

    Authors: Resha Dermawansyah Rusman, Nu’man AS Daud, Muhammad Luthfi Parewangi, Syakib Bakri, Andi Makbul Aman, Haerani Rasyid, Arifin Seweng and Akiko Syawalidhany Tahir
    Citation: Egyptian Liver Journal 2022 12:52
    Content type: Original Research Article Published on:

  25. Infection with coronavirus disease 2019 (COVID-19) can progress to the multisystem inflammatory syndrome in children (MIS-C). Patients with liver cirrhosis are at increased risk of complications.

    Authors: Tawhida Yassin Abdel-Ghaffar, Haidy Mohammed Zakaria, Eman Mohamed Elsayed, Sondos Magdy, Suzan El Naghi, Suhaib Alsayed Mohammed Naeem, Mahmoud Yosry Hasan and Rabab Qasim khallaf
    Citation: Egyptian Liver Journal 2022 12:51
    Content type: Case report Published on:

  26. Outcome of HCV treatment with direct antiviral agents in malignant patients is questionable. The aim is to assess the safety and efficacy of DAAs in treatment of chronic HCV patients who received chemotherapy ...

    Authors: Mira Atef, Rasha Eletreby, Mohamed Abdallah, Rasha Salama, Wafaa Elakel, Mohamed Hassany, Wael Abdel-Razek, Yehia El Shazly, Wahid Doss and Gamal Esmat
    Citation: Egyptian Liver Journal 2022 12:50
    Content type: Original Research Article Published on:

  27. Hepatitis C virus is a viral infection associated with autoimmune disorders. This virus has hepatic and extrahepatic manifestations. One of the extrahepatic manifestations associated with the hepatitis C virus...

    Authors: Suraiya Hirani, Amynah Charania, Sandhiya Salim and Sanam Faheem
    Citation: Egyptian Liver Journal 2022 12:49
    Content type: Review Published on:

  28. Liver resection and local ablation are the two primary curative treatments for early-stage hepatocellular carcinoma (HCC). Microwave ablation (MWA) shows promising performance in terms of early tumor response,...

    Authors: Ayman M. A. Osman, Ashraf Omar Abdelaziz, Mahmoud Deweir, Ayman Salah, Shady Tarek Elghazaly Harb, Mohamed Mahmoud Nabeel, Ahmed Hosni Abdelmaksoud, Hend Ibrahim Shousha, Tamer Mahmoud Elbaz and Mohamed B. Hashem
    Citation: Egyptian Liver Journal 2022 12:48
    Content type: Original Research Article Published on:

  29. The SAF score (steatosis, activity, and fibrosis) has been developed for the assessment of the histological severity of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The aim...

    Authors: Ahmed El Ray, Valerie Paradis, Ahmed Montasser, Maged Elghannam, Mohamed Shemis, Iris Nessim, Hoda Abu-Taleb, Tarik Asselah, Ashiq Mohamed, Nicolas Poté, Maha Akl and Patrick Marcellin
    Citation: Egyptian Liver Journal 2022 12:47
    Content type: Original Research Article Published on:

  30. Hepatitis B virus (HBV) infection is a major worldwide healthcare problem with subsequent serious complications including cirrhosis and hepatocellular carcinoma (HCC). Hence, taking cognizance of HBV impact is...

    Authors: Eman Raslan, Mohamed AbdAllah and Saeed Soliman
    Citation: Egyptian Liver Journal 2022 12:46
    Content type: Original Research Article Published on:

  31. Liver cirrhosis is the last phase of chronic hepatitis C virus infection. During the compensated phase, portal pressure is still below the point where varices start to form. On the contrary, decompensated indi...

    Authors: Abdelfattah Hanno, Ali M. EL-Kady, Essam Bedewy, Reham A. Abo Elwafa and Mohammed S. Ahmed
    Citation: Egyptian Liver Journal 2022 12:45
    Content type: Original Research Article Published on:

  32. Acetaminophen overdose is the leading cause of acute liver injury (ALI) and acute liver failure (ALF) in the developed world. We aimed at studying the therapeutic potential of bone marrow mesenchymal stem cell...

    Authors: Hanaa Ahmed El-Araby, Gihan Ahmed Sobhy, Suhaib Alsayed Mohammed Naeem, Aly Fahmy Mohamed Alsayed, Haidy Mohammed Zakaria and Mohammed Ahmed Khedr
    Citation: Egyptian Liver Journal 2022 12:44
    Content type: Original Research Article Published on:

  33. Coronavirus causes an outbreak of viral pneumonia that spread throughout the world. Liver injury is becoming more widely recognized as a component of the clinical picture of COVID-19 infection. Hepatitis with ...

    Authors: Maged T. Elghannam, Moataz H. Hassanien, Yosry A. Ameen, Gamal M. ELattar, Ahmed A. ELRay, Emad A. Turky and Mohammed D. ELTalkawy
    Citation: Egyptian Liver Journal 2022 12:43
    Content type: Review Published on:

  34. Hepatocellular carcinoma (HCC) represents the sixth most common cancer worldwide and the fourth in Egypt. Persistent inflammation and specific somatic mutations in driving genes play a major role in the develo...

    Authors: Marwa A. Abdel-Wahed, Eman Mohamed Abdel Rahman Amer, Ramy Mohamed Mahmoud, Iman Fawzy Montasser, Yassmin M. Massoud, Perihan Hamdy and Safeya Hamdy Zakaria Hassan
    Citation: Egyptian Liver Journal 2022 12:42
    Content type: Original Research Article Published on:

  35. Wilson’s disease (WD) is a rare genetic disorder of copper metabolism that results in dysfunction of copper excretion into bile leading to its accumulation in the liver, brain, cornea, and kidney. Only a few e...

    Authors: Hani Sayed Aboalam, Marwa Khalaf Hassan, Nada El-domiaty, Nagat Faisal Ibrahim, Anwar M. Ali, Wesam Hassan, Esam Ghanem Abu El Wafa, Ashraf Elsaghier, Helal F. Hetta, Mohamed Elbadry and Mohamed El-Kassas
    Citation: Egyptian Liver Journal 2022 12:41
    Content type: Review Published on:

  38. Regional adiposity has a significant impact on the formation of adverse metabolic and cardiovascular risk profiles. While much of the attention was directed to the importance of intra-abdominal adipose tissue,...

    Authors: Hany Samir Rasmy, Ahmed Shaaban Hamed, Salah El Demerdash, Hanan Hafez Zeidan and Sameh Attia Amin
    Citation: Egyptian Liver Journal 2022 12:38
    Content type: Original Research Article Published on:

  39. Without firm diagnostic criteria, the exact prevalence of cirrhotic cardiomyopathy still remains unknown. Its estimation is rather a difficult task as the disease is generally latent and shows itself only when...

    Authors: Hatem H. Al Atroush, Khaled H. Mohammed, Fatma M. Nasr, Mohammed I. Al Desouky and Mohammed A. Rabie
    Citation: Egyptian Liver Journal 2022 12:37
    Content type: Original Research Article Published on:

  40. Out of the 185 million people infected with hepatitis C virus (HCV) worldwide according to the World Health Organization (WHO), Egypt had the highest prevalence of HCV reaching 13% of its population with an es...

    Authors: Howayda Abd Elhameed Elshinnawy, Iman Ibrahim Sarhan, Ossama Ashraf Ahmed, Meryhan Osama Mohamed and Cherry Reda Kamel
    Citation: Egyptian Liver Journal 2022 12:36
    Content type: Original Research Article Published on:

  41. Non-alcoholic fatty liver disease (NAFLD) and its subtype non-alcoholic steatohepatitis (NASH) are increasing worldwide. NASH is characterized by active liver inflammation with severe consequences including pr...

    Authors: Ayman Mohamed Shamseya, Mohamed Tamer Afify, Hussam Ahmed Shawki Fayad and Mohamed Mahmoud Elshafey
    Citation: Egyptian Liver Journal 2022 12:35
    Content type: Original Research Article Published on:

  42. Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are two different pathologies that cause bleeding in cirrhotic patients. These two pathologies are still difficult to be disting...

    Authors: Randa Salah Eldin Abdelmoneim, Amr Aly Abdelmoety, Nahed Baddour, Perihan Salem and Marwa Metawea
    Citation: Egyptian Liver Journal 2022 12:34
    Content type: Original Research Article Published on:

  43. Elderly people are a vulnerable group of patients subjected to multiple health problems. Upper gastrointestinal bleeding (UGIB) in older adults is a frequent cause of hospital admissions. The presence of multi...

    Authors: Maha Hossam, Soheir Abdel-Fattah, Shaimaa Elkholy, Yomna Khaled and Abeer Awad
    Citation: Egyptian Liver Journal 2022 12:33
    Content type: Original Research Article Published on:

  44. Infection with the hepatitis C virus (HCV) is a worldwide health problem. HCV infection is linked to a variety of metabolic abnormalities as it interferes with lipid metabolism, causing steatosis and a wide ra...

    Authors: Ahmed Samir Allam, Mohamed Lotfy Abd Elmeged, Sameh Mohamed Ghaly, Osama Ashraf Ahmed, Gina Gamal Naguib and Ahmed Samir Abohalima
    Citation: Egyptian Liver Journal 2022 12:32
    Content type: Original Research Article Published on:

  45. Declining eosinophil count has recently been associated with sepsis. Thus, absolute eosinophil count (AEC) can be used as a marker of the severity of sepsis, which helps in the early identification of high-ris...

    Authors: K. V. Anoop, Krishnadas Devadas and Jijo Varghese
    Citation: Egyptian Liver Journal 2022 12:31
    Content type: Original Research Article Published on:

  47. A choledochal cyst is a relatively rare congenital anomaly of the biliary tree requiring surgery as the definitive treatment. Amongst the five Todani variants, type I poses a diagnostic and treatment challenge...

    Authors: Deo Justine Hando, Daniel William Kitua, Mbelwa Dennis Bitesigilwe, JohnofGod Leonce Mutajwaha, Mogolodi Gabolwelwe, Hassan Mwinchande Chande, Ally Hamisi Mwanga, Zaitun Mohammed Bokhary and Petronilla Joseph Ngiloi
    Citation: Egyptian Liver Journal 2022 12:29
    Content type: Case report Published on:

  48. Budd-Chiari syndrome (BCS) is a rare vascular disease of the liver, characterised by occlusion of the venous outflow tract. Cancer, pyogenic liver infection, and prothrombotic haematological conditions are the...

    Authors: Alexandre Pérez-González, Ana Argibay, Rut Lorenzo-Castro, Ignacio Martín-Granizo and Alberto Rivera-Gallego
    Citation: Egyptian Liver Journal 2022 12:28
    Content type: Original Research Article Published on:

  49. Portal hypertension (PH) is a common consequence in hepatitis C virus cirrhotic patients. With interferon alpha-based therapy, SVR was linked to improved PH and fibrosis regression. SVR to oral antiviral regim...

    Authors: Heba Ahmed Faheem, Nannes Adel Abdulmeged, Hany Aly Hussein, Ahmed Abdelaziz Elmoursi, Heba T-allah Mohammed Yousry Elnaggar and Ramy Samir Ghait
    Citation: Egyptian Liver Journal 2022 12:27
    Content type: Original Research Article Published on:

  50. Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder characterised by enhanced hepatic fat deposition and inflammation. Efforts to manage NAFLD are limited by the poorly characterised pathological...

    Authors: Manal Sabry Mohamed, Sameh Ghaly, Karim Hamed Azmy and Ghada Abdelrahman Mohamed
    Citation: Egyptian Liver Journal 2022 12:26
    Content type: Original Research Article Published on:
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  • ISSN: 2090-6226 (electronic)