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  1. Hepatocellular carcinoma is a major public health problem, as is considered the fastest growing cause of cancer-related death. Cannonball metastases as an initial finding in hepatocellular carcinoma are consid...

    Authors: Héctor Raúl Ibarra-Sifuentes, Gustavo Abraham Canales-Azcona, Jaqueline Isabel Gómez-Arredondo and Carlos Javier Rodríguez-Álvarez
    Citation: Egyptian Liver Journal 2024 14:25
  2. Eosinophilic ascites is non-common and challenging disease. This study aimed to describe the clinical presentation and treatment of eosinophilic ascites.

    Authors: Mohammed Ahmed Medhat, Mohamed O. Abdelmalek, Mohamed A. Mekky, Sherief Abd-Elsalam, Mohamed Ahmed Yehya Abdel-Malek, Sayed Hassan Ahmed, Yusuf S. Amry and Waleed Attia Hassan
    Citation: Egyptian Liver Journal 2024 14:24
  3. HBV infection is a significant concern in dialysis patients, influenced by various factors. This study aims to investigate the impact of serum uric acid levels on the immunogenicity of hepatitis Bvaccination i...

    Authors: Nasibe Golestani, Najmeh Shamspour, Jalal Azmandian, Habibeh Ahmadipour and Mahdi Karamipour zarei
    Citation: Egyptian Liver Journal 2024 14:23
  4. Obesity is a global health problem and has been increasing in Egypt over the last several decades. A national population screening program for hepatitis C included screening for obesity. Here we report the out...

    Authors: Gamal Esmat, Hala Zaid, Mohamed Hassany, Wael Abdel-Razek, Magdy El-Serafy, Wafaa El Akel, Aysam Salah, Ehab Kamal, Galal Elshishiney, Islam Ammar, Khaled Kabil, Mohamed AbdAllah, Ramy Saeed, Tarek Saad, Yasser Omar, Hany Dabbous…
    Citation: Egyptian Liver Journal 2024 14:22
  5. A prevalent liver condition called non-alcoholic fatty liver disease (NAFLD) may progress into non-alcoholic steatohepatitis (NASH) and cause life-threatening complications like cirrhosis and liver cancer. The...

    Authors: Pranali A. Jadhav, Asha B. Thomas, Rabindra K. Nanda and Sohan S. Chitlange
    Citation: Egyptian Liver Journal 2024 14:21
  6. Hepatic energy metabolism is intricately linked with the metabolic changes associated with HCV infection and hepatocellular carcinoma (HCC). This study investigated the potential of carnitine and acylcarnitine...

    Authors: Ashraf Abbass, Azza El Sheashaey, Ashraf El Fert, Manar Obada, Eman Abdelsameea, Mohammed Abdel-Samiee, Asmaa Ibrahim and Ashraf Khalil
    Citation: Egyptian Liver Journal 2024 14:19
  7. NS5A inhibitors are an important option for treating chronic HCV-GT4 patients. Retreatments after NS5A-based DAAs failure are limited. We aimed to determine the effectiveness and safety of SOF/VEL-containing r...

    Authors: Heba Omar, Mohammed Hamdy Abdel Maksoud, Ahmed A. Goma, Essam A. Hassan, Nancy Abdalla Atta, Mahmoud Khalil, Mohamed Soliman Hegazy, Samy Zaky and Gamal Esmat
    Citation: Egyptian Liver Journal 2024 14:18
  8. Biliary atresia (BA) is an obliterative cholangiopathy of infancy that results in cholestasis and liver fibrosis. This fibrosis is due to an imbalance in extracellular matrix (ECM) breakdown and deposition. Th...

    Authors: Alif Abdelhakim Allam, Mohammed Ahmed Khedr, Shimaa Saad Elkholy, Takwa Abd El Rahman Yassin and Ola Ahmed Fouad
    Citation: Egyptian Liver Journal 2024 14:17
  9. Alterations of hemostasis in patients with decompensated cirrhosis are complex. Accordingly, standard coagulation tests are not feasible to evaluate bleeding risk in these patients. The aim of this study was t...

    Authors: Mona A. Abu El-Makarem, Aml A. Mohammad, Ola A. Afifi, Nehal I. Abbas, Tarek A. Abd El-Zaher, Safaa M. Abdel Halim and Aliaa S. Abd El-Fattah
    Citation: Egyptian Liver Journal 2024 14:16
  10. Liver fibrosis is an irreversible liver destruction. Apigenin (API) has different pharmacological properties as anticancer, anti-inflammatory, and antioxidant; however, API hepatoprotective and therapeutic eff...

    Authors: Zaenah Zuhair Alamri
    Citation: Egyptian Liver Journal 2024 14:15
  11. Chronic hepatitis C virus (HCV) infection negatively impacts health-related quality of life (HRQL). We aimed to assess patient-reported outcomes (PROs) to evaluate the impact of treating chronic HCV with direc...

    Authors: Mohamed Elbadry, Mahmoud Badawi, Naglaa Youssef, Martin Duracinsky, Shereen A. Saleh, Anna Funk, Hagar Elessawy, Eva Rumpler, Khadiga Sayed, Anca Vasiliu, Yoann Madec, Arnaud Fontanet and Mohamed El-Kassas
    Citation: Egyptian Liver Journal 2024 14:14
  12. Chronic hepatitis B virus (HBV) infection poses a significant global health challenge, impacting millions of individuals and elevating the risk of morbidity and mortality. Antiviral therapies are the primary t...

    Authors: Syed Ayaz Kazmi, Abdul Rauf, Muhammad Zahid Latif, Beenish Shahid, Sundus Khawaja and Zeeshan Anjum
    Citation: Egyptian Liver Journal 2024 14:13
  13. Liver cirrhosis (LC) advances from an asymptomatic phase (compensated cirrhosis) to a symptomatic phase (decompensated cirrhosis). Up to 80% of patients with LC may experience minimal hepatic encephalopathy (M...

    Authors: Essam S. Bedewy, Abeer Elhadidi, Naglaa Abd El-Latif, Yousra T. El Zawawy and Amany N. Abbasy
    Citation: Egyptian Liver Journal 2024 14:12
  14. Esophageal varices are abnormally dilated submucosal veins of the esophagus which develop as a result of portal hypertension due to cirrhosis. Collagen type IV is upregulated with a 14-fold increase in cirrhos...

    Authors: Nasser Mohamed Abdalla, Fatma Mohamed Abd El Aziz, Akram Deghady, Mohamed Helmy Abaza and Walid Ismail Ellakany
    Citation: Egyptian Liver Journal 2024 14:11
  15. People all around the world are affected by primary liver cancers like hepatocellular carcinoma (HCC), which is usually associated with cirrhosis. Early HCC detection is crucial for better prognosis, but effec...

    Authors: Khaled Mahmoud Mohiedeen, Mona Moustafa Tahoon, Christina Samir Sadek Hanna and Mohamed Adel Abdel Aziz
    Citation: Egyptian Liver Journal 2024 14:10
  16. Pregnancy is not uncommon in patients with non-cirrhotic portal hypertension. Rupture of a splenic artery aneurysm remains a rare complication, associated with a very poor maternal–fetal prognosis. Our aim is ...

    Authors: Chantelli Iamblaudiot Razafindrazoto, Antsa Fihobiana Randrianiaina, Behoavy Mahafaly Ralaizanaka, Henintsoa Rakotoniaina, Nitah Harivony Randriamifidy, Anjaramalala Sitraka Rasolonjatovo, Andry Lalaina Rinà Rakotozafindrabe, Tovo Harimanana Rabenjanahary, Soloniaina Hélio Razafimahefa and Rado Manitrala Ramanampamonjy
    Citation: Egyptian Liver Journal 2024 14:9
  17. Non-alcoholic fatty liver disease (NAFLD) is a liver pathology. NAFLD’s prevalence is increasing in the world and because of the increase non-invasive methods are gaining importance in diagnosis. The Fibrosis ...

    Authors: Kutay Kirdok, Özge Yogurtcu, Tahir Buran and Elmas Kasap
    Citation: Egyptian Liver Journal 2024 14:8
  18. Pancreatic adenocarcinoma, recognized for its aggressive behavior and frequent late-stage diagnosis, imposes significant challenges in early detection and prognosis. This study aimed to evaluate the diagnostic...

    Authors: Ghada Salah, Manar Obada, Dina Sweed, Ibrahim Abdelkader Salama, Ashraf Khalil and Shimaa Abdelsattar
    Citation: Egyptian Liver Journal 2024 14:6
  19. Tetrahydrobiopterin deficiency in newborns with atypical hyperphenylalaninemia requires rapid and accurate diagnosis and the ability to distinguish it from the classical type to prevent early irreversible neur...

    Authors: Nadia Salama, Gamalte Elgedawy, Radwa Gamal, Osama Zaki, Ashraf Khalil and Manar Obada
    Citation: Egyptian Liver Journal 2024 14:5
  20. Hepatocellular carcinoma (HCC) is a highly aggressive and rapidly progressing form of cancer with a poor prognosis. Recent advances in the management of HCC focused on the novel immunotherapeutic modalities fo...

    Authors: Kashif Asghar, Shaarif Bashir, Muhammad Hassan, Asim Farooq, Muhammad Abu Bakar, Sundus Bilal, Maryam Hameed, Shafqat Mehmood and Asif Loya
    Citation: Egyptian Liver Journal 2024 14:4
  21. Hepatocellular carcinoma (HCC) is one of the most prevalent and fatal malignancies worldwide. Following an increase in reactive oxygen species (ROS), cancer cells enter an oxidative stress state. As a result, ...

    Authors: Khaled Mohamed Abdelwahab, Wesam Ahmed Ibrahim, Shereen Abou Bakr Saleh, Anas Abdelfattah Abdelaziz Elbarky and Ghada Abdelrahman Mohamed
    Citation: Egyptian Liver Journal 2024 14:3
  22. Hepatocellular carcinoma (HCC) is a common type of liver cancer, with a high mortality rate. Hepatocellular carcinoma is a type of liver cancer that can be effectively managed through early detection and accur...

    Authors: Tamer A. Addissouky, Ibrahim El Tantawy El Sayed, Majeed M. A. Ali, Yuliang Wang, Ayman El Baz, Ahmed A. Khalil and Naglaa Elarabany
    Citation: Egyptian Liver Journal 2024 14:2
  23. Acute gastrointestinal bleeding (GIB) is a significant medical condition that poses a considerable burden on healthcare systems worldwide. To effectively manage and improve outcomes for patients, it is essenti...

    Authors: Edite Sadiku, Liri Cuko, Ina Pasho, Orion Jucja, Stela Taci, Kliti Hoti and Bledar Kraja
    Citation: Egyptian Liver Journal 2024 14:1
  24. Pancreatic neuroendocrine tumors (PNET) account for less than 2% of all pancreatic tumors, while cystic PNETs account for only 10–18% of all resected PNETs. The most common site for metastasis is the liver. Fe...

    Authors: Maham Nasir Uddin, Muhammad Arsalan Khan and Abdaal Waseem Khan
    Citation: Egyptian Liver Journal 2023 13:69
  25. Colonic perforation usually presents with classical signs of peritonitis. However, isolated retroperitoneal colonic perforation can present with varied clinical signs and symptoms and pose diagnostic challenge...

    Authors: Kulbhushan Haldeniya, S. R. Krishna, Annagiri Raghavendra and Pawan Kumar Singh
    Citation: Egyptian Liver Journal 2023 13:68
  26. Malaria is an endemic mosquito-borne disease in sub-Saharan regions, including Cameroon. Due to the obligatory hepatic stage of its pathogenic agents, malaria can induce liver damage if not properly treated. H...

    Authors: Arnaud Fondjo Kouam, Noé Auguste Nseké Ngoumé, Armelle Gaelle Kwesseu Fepa, Zerubabel Wainfen, Eléonore Ngounou, Borris Rosnay Tietcheu Galani, Nembu Erastus Nembo, Pascal Dieudonné Djamen Chuisseu, Fréderic Nico Njayou and Paul Fewou Moundipa
    Citation: Egyptian Liver Journal 2023 13:67
  27. Liver cirrhosis (LC) has a significant impact in quality of life, and it is frequently linked to loss of a job, mood fluctuations, anxiety, low self-esteem, and despair. Recent LC treatment primarily focuses o...

    Authors: Syifa Mustika, Jefri Pratama Susanto and Cosmas Rinaldi Adithya Lesmana
    Citation: Egyptian Liver Journal 2023 13:66
  28. Background The most common cause of benign biliary stricture is bile duct injury after cholecystectomy. Benign biliary strictures are associated with a broad spectrum of signs and symptoms, ranging from subclinic...

    Authors: Kulbhushan Haldeniya, Niranjan Rajkumar Gandhi, Haritha Gorantla and Sindhura Bukka
    Citation: Egyptian Liver Journal 2023 13:65
  29. H. Pylori is one of the commonest infectious diseases worldwide. In recent years, PPI-based triple therapy has been described to be losing its efficacy against H. pylori due to high rates of antibiotic resistance...

    Authors: Sameh Mohamed Fakhry, Mohamed Abdel-Hameed Kandyl, Adel Ferig Hashish, Wafaa Kandeel, Ahmed Mostafa El-Shenawy, Hoda Samir El-Sayed, Mohamed Kamal Dewidar, Sameh Mohamed Badr and Nayra Shaker Mehanna
    Citation: Egyptian Liver Journal 2023 13:64
  30. NAFLD is a spectrum of disorders ranging from hepatic steatosis to nonalcoholic steatohepatitis (NASH), NASH related cirrhosis and hepatocellular carcinoma (HCC). There is sparse data on the prevalence CKD in ...

    Authors: Heba El Sayed Kasem, Ehab Ahmed Abdelatty, Ahmed Mohamed Mokhtar Yahia and Ezzat Mohamed Abdalla
    Citation: Egyptian Liver Journal 2023 13:63
  31. Alagille syndrome is a rare autosomal-dominant disorder, representing 10 to 15% of the causes of neonatal cholestasis with no gender predominance. The diagnosis is based on the association of liver, heart, eye...

    Authors: Oussama Kharmach, Mohamed Borahma and Fatima-Zohra Ajana
    Citation: Egyptian Liver Journal 2023 13:62
  32. Liver biopsy is crucial to know if the tumor is benign or malignant. This paper has reviewed the literature clinically shedding lights on the present biopsy procedure, requirements, and potential challenges. T...

    Authors: Serah Jessy Mathew, Anchal Nayak, Sagnika Dash and Sarada Prasad Dakua
    Citation: Egyptian Liver Journal 2023 13:61
  33. Endoscopic variceal ligation (EVL) is a crucial procedure for the primary and secondary prevention of variceal bleeding. The objective of this study was to evaluate the efficacy and tolerability of EVL in the ...

    Authors: Chantelli Iamblaudiot Razafindrazoto, Nitah Harivony Randriamifidy, Jolivet Auguste Rakotomalala, Sedera Radoniaina Rakotondrasoa, Behoavy Mahafaly Ralaizanaka, Henintsoa Rakotoniaina, Antsa Fihobiana Randrianiaina, Mialitiana Rakotomaharo, Domoina Harivonjy Hasina Laingonirina, Sonny Maherison, Anjaramalala Sitraka Rasolonjatovo, Andry Lalaina Rinà Rakotozafindrabe, Tovo Harimanana Rabenjanahary, Soloniaina Hélio Razafimahefa and Rado Manitrala Ramanampamonjy
    Citation: Egyptian Liver Journal 2023 13:60
  34. Brain-derived neurotrophic factor (BDNF) functions not only in the brain but also in peripheral tissues such as the liver. Genetic factors determine the development of alcohol dependence and somatic consequenc...

    Authors: Danil I. Peregud, Valeria Yu. Baronets, Anna S. Lobacheva, Alexandr S. Ivanov, Irina V. Garmash, Olga S. Arisheva, Zhanna D. Kobalava, Sergey V. Pirozhkov and Natalia N. Terebilina
    Citation: Egyptian Liver Journal 2023 13:59
  35. The natural history of pancreatic branch duct-type intraductal papillary mucinous neoplasms (BD-IPMNs) is still unknown. This retrospective study aims to determine the morphological changes of BD-IPMNs with at...

    Authors: Akira Imoto, Takeshi Ogura, Daisuke Masuda, Ken Narabayashi, Toshihiko Okada, Yosuke Abe, Toshihisa Takeuchi, Takuya Inoue, Kumi Ishida, Sadaharu Nouda, Kazuhide Higuchi and Usama M. Abdelaal
    Citation: Egyptian Liver Journal 2023 13:58
  36. Non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver disease in type-2 diabetics. The quality of life among those patients was not explored well. Hence, the present study aim...

    Authors: Usha Sree Puneem, Vanitha Rani Nagasubramanian, Vasudeva Murthy Sindgi, Subburaya Mudaliyar Rajendran Ramakrishnan and Ranakishor Pelluri
    Citation: Egyptian Liver Journal 2023 13:57
  37. Decompensated liver cirrhosis (DLC) is now known as a chronic inflammatory process, evidenced by elevated levels of circulatory pro-inflammatory cytokines and chemokines which in turn lead to the development o...

    Authors: Ayman F. El-Shayeb, Akram A. Degheidy, Sawsan El-Mallah, John Farid and Amany N. Abbasy
    Citation: Egyptian Liver Journal 2023 13:56
  38. Patients with chronic liver disease (CLD) as chronic hepatitis C (CHC) are at high risk of diabetes type 2 (T2D). Genetic factors are suggested to modulate diabetes development in cirrhotic patients. TCF7L2 ge...

    Authors: Mona Mahmoud Hassouna, Mohammed Sayed Moustafa, Mona Hamdy, Eman Abdelsameea, Mohamed Abbasy and Mary Naguib
    Citation: Egyptian Liver Journal 2023 13:54
  39. In malaria-endemic countries, repeated intake of artemisinin-based combination therapies (ACTs) is rampant and driven by drug resistance, improper usage, and easy accessibility. Stress effects and potential li...

    Authors: David Audu, Vinood B. Patel, Olufunmilayo A. Idowu, Fakilahyel M. Mshelbwala and Adewumi B. Idowu
    Citation: Egyptian Liver Journal 2023 13:53
  40. Contrast-enhanced magnetic resonance imaging (MRI) plays a crucial role in the diagnosis of hepatocellular carcinoma (HCC). This study aims to assess the performance of MRI features for evaluating hepatocellul...

    Authors: Aylin Altan Kus, Selim Keceoglu and Ali Ozer
    Citation: Egyptian Liver Journal 2023 13:52
  41. Hepatitis B virus (HBV) and hepatitis C virus (HCV) are amongst the most common causative agents of viral hepatitis with its severe complications, including liver cirrhosis, decompensation, and hepatocellular ...

    Authors: Aisha Elsharkawy, Reham Samir, Mohamed Abdallah, Mohamed Hassany and Mohamed El-Kassas
    Citation: Egyptian Liver Journal 2023 13:50
  42. Regression of fibrosis and improvement of portal hemodynamics after achievement of sustained viral response (SVR) in patients with chronic hepatitis C (HCV) is a subject of debate in different studies. Some st...

    Authors: Waleed Attia Hassan, Sherif I. Kamel, Ibrahim Abdel Naby Mahmoud, Nahed Makhlouf, Mahmoud Moubark and Sahar M. Hassany
    Citation: Egyptian Liver Journal 2023 13:49
  43. Tamiflu (Oseltamivir) and Adamine (Amantadine HCl) are antiviral drugs which are used for prevention and treatment for influenza. The present study was carried out to evaluate the effect of Tamiflu and Adamine...

    Authors: Nagla Zaky Ibrahim El-Alfy, Samia Mohamed Sakr, Mahmoud Fathy Mahmoud and Heba Ahmed Omar
    Citation: Egyptian Liver Journal 2023 13:46

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