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Egyptian Liver Journal
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  1. Non-pharmacological exposure or pharmacological drug-induced hepatic injury is the most common cause of hepatotoxicity. This study was conducted to evaluate the effect of Moringa oleifera leaf extract against bis...

    Authors: Yasmin A. Abd-Elnaby, Ibrahim E. ElSayed, Mabrouk A. AbdEldaim, Eman A. Badr, Mona M. Abdelhafez and Ibrahim Elmadbouh
    Citation: Egyptian Liver Journal 2022 12:57
    Content type: Original Research Article Published on:

  2. Genetic variants of Patatin-like phospholipase domain-containing protein 3 (PNPLA3) and transmembrane 6 superfamily member 2 (TM6SF2) genes have been reported with the development of hepatocellular carcinoma (...

    Authors: Samar Samir Youssef, Eman Abd El Razek Abbas, Asmaa M. Elfiky, Sameh Seif, Mohamed Mahmoud Nabeel, Hend Ibrahim Shousha and Ashraf Omar Abdelaziz
    Citation: Egyptian Liver Journal 2022 12:56
    Content type: Original Research Article Published on:

  3. Telmisartan is a non-peptide angiotensin II receptor antagonist which acts by ACE/AngII/AT1 axis blockade (ARB). In the last years increasing evidence of its metabolic benefits pointed out this drug as the mos...

    Authors: Luciana Mendes Araújo Borém, Daniela Fernanda Freitas, Amanda Souto Machado, Alanna Fernandes Paraíso, Bruna Viana Caldas, João Felício Rodrigues Neto, Juliana Pinto Lima, André Luiz Sena Guimarães, Alfredo Maurício Batista de Paula and Sérgio Henrique Sousa Santos
    Citation: Egyptian Liver Journal 2022 12:55
    Content type: Original Research Article Published on:

  4. Recent studies suggested association between hepatitis C virus (HCV) infection and cardiovascular disorders, including carotid atherosclerosis with evidence of an effect of HCV clearance on carotid atheroscler...

    Authors: Marwa Ahmed Mohamed, Essam M. Bayoumy, Mostafa Mohamed Swailam and Ahmed Samir Allam
    Citation: Egyptian Liver Journal 2022 12:54
    Content type: Original Research Article Published on:

  5. Despite the effectiveness of new therapies and awareness campaigns, the number of seropositive patients is increasing every year. Recently, other causes of death, not directly related to HIV, have emerged, suc...

    Authors: Francesco Cammarata, Laura Benuzzi, Michele Crespi, Albert Troci, Luca Pennacchi, Monica Schiavini and Diego Foschi
    Citation: Egyptian Liver Journal 2022 12:53
    Content type: Original Research Article Published on:

  6. Hepatitis C virus (HCV) infection is the global epidemic of this century, affecting almost 100 million people, and it is now the leading cause of liver-related mortality and liver transplantation. Interferon (...

    Authors: Resha Dermawansyah Rusman, Nu’man AS Daud, Muhammad Luthfi Parewangi, Syakib Bakri, Andi Makbul Aman, Haerani Rasyid, Arifin Seweng and Akiko Syawalidhany Tahir
    Citation: Egyptian Liver Journal 2022 12:52
    Content type: Original Research Article Published on:

  7. Infection with coronavirus disease 2019 (COVID-19) can progress to the multisystem inflammatory syndrome in children (MIS-C). Patients with liver cirrhosis are at increased risk of complications.

    Authors: Tawhida Yassin Abdel-Ghaffar, Haidy Mohammed Zakaria, Eman Mohamed Elsayed, Sondos Magdy, Suzan El Naghi, Suhaib Alsayed Mohammed Naeem, Mahmoud Yosry Hasan and Rabab Qasim khallaf
    Citation: Egyptian Liver Journal 2022 12:51
    Content type: Case report Published on:

  8. Outcome of HCV treatment with direct antiviral agents in malignant patients is questionable. The aim is to assess the safety and efficacy of DAAs in treatment of chronic HCV patients who received chemotherapy ...

    Authors: Mira Atef, Rasha Eletreby, Mohamed Abdallah, Rasha Salama, Wafaa Elakel, Mohamed Hassany, Wael Abdel-Razek, Yehia El Shazly, Wahid Doss and Gamal Esmat
    Citation: Egyptian Liver Journal 2022 12:50
    Content type: Original Research Article Published on:

  9. Hepatitis C virus is a viral infection associated with autoimmune disorders. This virus has hepatic and extrahepatic manifestations. One of the extrahepatic manifestations associated with the hepatitis C virus...

    Authors: Suraiya Hirani, Amynah Charania, Sandhiya Salim and Sanam Faheem
    Citation: Egyptian Liver Journal 2022 12:49
    Content type: Review Published on:

  10. Liver resection and local ablation are the two primary curative treatments for early-stage hepatocellular carcinoma (HCC). Microwave ablation (MWA) shows promising performance in terms of early tumor response,...

    Authors: Ayman M. A. Osman, Ashraf Omar Abdelaziz, Mahmoud Deweir, Ayman Salah, Shady Tarek Elghazaly Harb, Mohamed Mahmoud Nabeel, Ahmed Hosni Abdelmaksoud, Hend Ibrahim Shousha, Tamer Mahmoud Elbaz and Mohamed B. Hashem
    Citation: Egyptian Liver Journal 2022 12:48
    Content type: Original Research Article Published on:

  11. The SAF score (steatosis, activity, and fibrosis) has been developed for the assessment of the histological severity of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The aim...

    Authors: Ahmed El Ray, Valerie Paradis, Ahmed Montasser, Maged Elghannam, Mohamed Shemis, Iris Nessim, Hoda Abu-Taleb, Tarik Asselah, Ashiq Mohamed, Nicolas Poté, Maha Akl and Patrick Marcellin
    Citation: Egyptian Liver Journal 2022 12:47
    Content type: Original Research Article Published on:

  12. Hepatitis B virus (HBV) infection is a major worldwide healthcare problem with subsequent serious complications including cirrhosis and hepatocellular carcinoma (HCC). Hence, taking cognizance of HBV impact is...

    Authors: Eman Raslan, Mohamed AbdAllah and Saeed Soliman
    Citation: Egyptian Liver Journal 2022 12:46
    Content type: Original Research Article Published on:

  13. Liver cirrhosis is the last phase of chronic hepatitis C virus infection. During the compensated phase, portal pressure is still below the point where varices start to form. On the contrary, decompensated indi...

    Authors: Abdelfattah Hanno, Ali M. EL-Kady, Essam Bedewy, Reham A. Abo Elwafa and Mohammed S. Ahmed
    Citation: Egyptian Liver Journal 2022 12:45
    Content type: Original Research Article Published on:

  14. Acetaminophen overdose is the leading cause of acute liver injury (ALI) and acute liver failure (ALF) in the developed world. We aimed at studying the therapeutic potential of bone marrow mesenchymal stem cell...

    Authors: Hanaa Ahmed El-Araby, Gihan Ahmed Sobhy, Suhaib Alsayed Mohammed Naeem, Aly Fahmy Mohamed Alsayed, Haidy Mohammed Zakaria and Mohammed Ahmed Khedr
    Citation: Egyptian Liver Journal 2022 12:44
    Content type: Original Research Article Published on:

  15. Coronavirus causes an outbreak of viral pneumonia that spread throughout the world. Liver injury is becoming more widely recognized as a component of the clinical picture of COVID-19 infection. Hepatitis with ...

    Authors: Maged T. Elghannam, Moataz H. Hassanien, Yosry A. Ameen, Gamal M. ELattar, Ahmed A. ELRay, Emad A. Turky and Mohammed D. ELTalkawy
    Citation: Egyptian Liver Journal 2022 12:43
    Content type: Review Published on:

  16. Hepatocellular carcinoma (HCC) represents the sixth most common cancer worldwide and the fourth in Egypt. Persistent inflammation and specific somatic mutations in driving genes play a major role in the develo...

    Authors: Marwa A. Abdel-Wahed, Eman Mohamed Abdel Rahman Amer, Ramy Mohamed Mahmoud, Iman Fawzy Montasser, Yassmin M. Massoud, Perihan Hamdy and Safeya Hamdy Zakaria Hassan
    Citation: Egyptian Liver Journal 2022 12:42
    Content type: Original Research Article Published on:

  17. Wilson’s disease (WD) is a rare genetic disorder of copper metabolism that results in dysfunction of copper excretion into bile leading to its accumulation in the liver, brain, cornea, and kidney. Only a few e...

    Authors: Hani Sayed Aboalam, Marwa Khalaf Hassan, Nada El-domiaty, Nagat Faisal Ibrahim, Anwar M. Ali, Wesam Hassan, Esam Ghanem Abu El Wafa, Ashraf Elsaghier, Helal F. Hetta, Mohamed Elbadry and Mohamed El-Kassas
    Citation: Egyptian Liver Journal 2022 12:41
    Content type: Review Published on:

  20. Regional adiposity has a significant impact on the formation of adverse metabolic and cardiovascular risk profiles. While much of the attention was directed to the importance of intra-abdominal adipose tissue,...

    Authors: Hany Samir Rasmy, Ahmed Shaaban Hamed, Salah El Demerdash, Hanan Hafez Zeidan and Sameh Attia Amin
    Citation: Egyptian Liver Journal 2022 12:38
    Content type: Original Research Article Published on:

  21. Without firm diagnostic criteria, the exact prevalence of cirrhotic cardiomyopathy still remains unknown. Its estimation is rather a difficult task as the disease is generally latent and shows itself only when...

    Authors: Hatem H. Al Atroush, Khaled H. Mohammed, Fatma M. Nasr, Mohammed I. Al Desouky and Mohammed A. Rabie
    Citation: Egyptian Liver Journal 2022 12:37
    Content type: Original Research Article Published on:

  22. Out of the 185 million people infected with hepatitis C virus (HCV) worldwide according to the World Health Organization (WHO), Egypt had the highest prevalence of HCV reaching 13% of its population with an es...

    Authors: Howayda Abd Elhameed Elshinnawy, Iman Ibrahim Sarhan, Ossama Ashraf Ahmed, Meryhan Osama Mohamed and Cherry Reda Kamel
    Citation: Egyptian Liver Journal 2022 12:36
    Content type: Original Research Article Published on:

  23. Non-alcoholic fatty liver disease (NAFLD) and its subtype non-alcoholic steatohepatitis (NASH) are increasing worldwide. NASH is characterized by active liver inflammation with severe consequences including pr...

    Authors: Ayman Mohamed Shamseya, Mohamed Tamer Afify, Hussam Ahmed Shawki Fayad and Mohamed Mahmoud Elshafey
    Citation: Egyptian Liver Journal 2022 12:35
    Content type: Original Research Article Published on:

  24. Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are two different pathologies that cause bleeding in cirrhotic patients. These two pathologies are still difficult to be disting...

    Authors: Randa Salah Eldin Abdelmoneim, Amr Aly Abdelmoety, Nahed Baddour, Perihan Salem and Marwa Metawea
    Citation: Egyptian Liver Journal 2022 12:34
    Content type: Original Research Article Published on:

  25. Elderly people are a vulnerable group of patients subjected to multiple health problems. Upper gastrointestinal bleeding (UGIB) in older adults is a frequent cause of hospital admissions. The presence of multi...

    Authors: Maha Hossam, Soheir Abdel-Fattah, Shaimaa Elkholy, Yomna Khaled and Abeer Awad
    Citation: Egyptian Liver Journal 2022 12:33
    Content type: Original Research Article Published on:

  26. Infection with the hepatitis C virus (HCV) is a worldwide health problem. HCV infection is linked to a variety of metabolic abnormalities as it interferes with lipid metabolism, causing steatosis and a wide ra...

    Authors: Ahmed Samir Allam, Mohamed Lotfy Abd Elmeged, Sameh Mohamed Ghaly, Osama Ashraf Ahmed, Gina Gamal Naguib and Ahmed Samir Abohalima
    Citation: Egyptian Liver Journal 2022 12:32
    Content type: Original Research Article Published on:

  27. Declining eosinophil count has recently been associated with sepsis. Thus, absolute eosinophil count (AEC) can be used as a marker of the severity of sepsis, which helps in the early identification of high-ris...

    Authors: K. V. Anoop, Krishnadas Devadas and Jijo Varghese
    Citation: Egyptian Liver Journal 2022 12:31
    Content type: Original Research Article Published on:

  29. A choledochal cyst is a relatively rare congenital anomaly of the biliary tree requiring surgery as the definitive treatment. Amongst the five Todani variants, type I poses a diagnostic and treatment challenge...

    Authors: Deo Justine Hando, Daniel William Kitua, Mbelwa Dennis Bitesigilwe, JohnofGod Leonce Mutajwaha, Mogolodi Gabolwelwe, Hassan Mwinchande Chande, Ally Hamisi Mwanga, Zaitun Mohammed Bokhary and Petronilla Joseph Ngiloi
    Citation: Egyptian Liver Journal 2022 12:29
    Content type: Case report Published on:

  30. Budd-Chiari syndrome (BCS) is a rare vascular disease of the liver, characterised by occlusion of the venous outflow tract. Cancer, pyogenic liver infection, and prothrombotic haematological conditions are the...

    Authors: Alexandre Pérez-González, Ana Argibay, Rut Lorenzo-Castro, Ignacio Martín-Granizo and Alberto Rivera-Gallego
    Citation: Egyptian Liver Journal 2022 12:28
    Content type: Original Research Article Published on:

  31. Portal hypertension (PH) is a common consequence in hepatitis C virus cirrhotic patients. With interferon alpha-based therapy, SVR was linked to improved PH and fibrosis regression. SVR to oral antiviral regim...

    Authors: Heba Ahmed Faheem, Nannes Adel Abdulmeged, Hany Aly Hussein, Ahmed Abdelaziz Elmoursi, Heba T-allah Mohammed Yousry Elnaggar and Ramy Samir Ghait
    Citation: Egyptian Liver Journal 2022 12:27
    Content type: Original Research Article Published on:

  32. Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder characterised by enhanced hepatic fat deposition and inflammation. Efforts to manage NAFLD are limited by the poorly characterised pathological...

    Authors: Manal Sabry Mohamed, Sameh Ghaly, Karim Hamed Azmy and Ghada Abdelrahman Mohamed
    Citation: Egyptian Liver Journal 2022 12:26
    Content type: Original Research Article Published on:

  33. Hepatitis C virus (HCV) is a significant cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma worldwide. Liver disease is not the only problem caused by chronic HCV infection; many extrahepatic ...

    Authors: Mohamed El-Kassas, Runia El-Folly, Maram Aboromia, Heba Aly, Mohamed Bahgat and Mostafa Hamed
    Citation: Egyptian Liver Journal 2022 12:25
    Content type: Original Research Article Published on:

  34. The aim of this prospective study is to compare the sensitivity and specificity of the liver shear wave elastography to the golden standard liver biopsy in staging liver fibrosis.

    Authors: A. R. Zayadeen, S. Hijazeen, M. Smadi, L. Fayyad, M. Halasa, S. AlQusous, O. AlRabadi, R. Hijazeen, Y. Ajlouni, K. Tulenko and P. Malik
    Citation: Egyptian Liver Journal 2022 12:24
    Content type: Original Research Article Published on:

  35. Hepatorenal syndrome is still a diagnosis of exclusion despite new classification.

    Authors: Mona Abd El-Rahman Abu El-Makarem, Yehia Zakaryia Mahmoud, Mahmoud Mohammed Moussa, Shereen Mohammed Mohammed El-Saghir and Hesham Kamal Habeeb Keryakos
    Citation: Egyptian Liver Journal 2022 12:23
    Content type: Original Research Article Published on:

  36. Although Ramadan fasting has a beneficial effect on health, the role of Ramadan fasting on patients with non-alcoholic fatty liver disease (NAFLD), as quantified by the controlled attenuation parameter (CAP), ...

    Authors: Ahmed Ibrahim Gad, Hesham Atia Abdel-Ghani and Amir Abd-elhameed Ahmed Barakat
    Citation: Egyptian Liver Journal 2022 12:22
    Content type: Original Research Article Published on:

  37. Acute-on-chronic liver failure (ACLF) is a distinct syndrome associated with high short-term mortality. Early identification of patients at high risk is essential to determine emergency for transplantation and...

    Authors: Talaat Zakareya, Mohamed Akl, Shereen Shibl, Mohamed El-Mazaly and Wael Abdel-Razek
    Citation: Egyptian Liver Journal 2022 12:21
    Content type: Original Research Article Published on:

  38. Inborn errors of metabolism (IEMs) represent a special challenge in pediatric practice. Despite the unquestionable clinical significance of newborn screening, it just offers a snapshot of an extremely minor su...

    Authors: Shimaa Abdelsattar, Manar Obada, Mahmoud A. El-Hawy, Sameh A. Abd El Naby, Osama K. Zaki and Hala Elsaid
    Citation: Egyptian Liver Journal 2022 12:20
    Content type: Original Research Article Published on:

  39. Early detection of hepatocellular carcinoma (HCC) is crucial for improving the survival rate for patients. Talin-1 is first identified as a cytoskeleton protein that is required for cell adhesion and motility ...

    Authors: El Said H. Ibrahim, Hend Naguib, Doaa M. Emara, Eman T. El Sayed and Marwa M. R. Tawfik
    Citation: Egyptian Liver Journal 2022 12:19
    Content type: Original Research Article Published on:

  40. Cirrhosis is the final result of most types of liver disease. Zinc, magnesium, and vitamin D have a significantly vital role in the immunologic and physiologic mechanisms in the body. The current study aimed t...

    Authors: Seyed Mohsen Dehghani, Anis Amirhakimi, Parisa Baligh and Hazhir Javaherizadeh
    Citation: Egyptian Liver Journal 2022 12:18
    Content type: Original Research Article Published on:

  41. Liver cirrhosis (LC) is the most common cause of portal hypertension. In chronic hepatitis C patients who are treated with direct-acting antiviral therapy (DAAS), the progression of cirrhosis can be reversed w...

    Authors: Alshymaa A. Hassnine, Wail Soliman, Amr M. Elsayed, Mahmoud M. Higazi, Mery Saied and Ehab M. Abdelraheem
    Citation: Egyptian Liver Journal 2022 12:17
    Content type: Original Research Article Published on:

  42. We prospectively evaluated the role of endoscopic ultrasound (EUS) in detecting the cause of common bile duct (CBD) dilatation in patients in whom trans-abdominal ultrasound (TUS) could not demonstrate the cau...

    Authors: Shereen Abou Bakr, Hagar Elessawy, Sameh Ghaly, Muhammed Abo Elezz, Ahmed Farahat and Mariam Salah Zaghloul
    Citation: Egyptian Liver Journal 2022 12:16
    Content type: Original Research Article Published on:

  44. Alcoholic liver disease (ALD) is the world’s most common type of liver disease caused due to overconsumption of alcohol. The liver supports the best level of tissue damage by hefty drinking since it is the bin...

    Authors: Ranjith Balakrishnan, Vajagathali Mohammed and Ramakrishnan Veerabathiran
    Citation: Egyptian Liver Journal 2022 12:14
    Content type: Review Published on:

  45. Hepatic encephalopathy (HE) is a serious condition associated with high rates of mortality. Many scoring systems are used to predict the outcome of HE in patients admitted to the intensive care unit (ICU). The...

    Authors: Mohamed Abbasy, Hassan Zaghla, Mostafa Elhelbawy, Mostafa Ramadan and Talaat Zakareya
    Citation: Egyptian Liver Journal 2022 12:13
    Content type: Original Research Article Published on:

  46. In March 2020, the World Health Organization declared coronavirus 2019 (COVID-19) a global pandemic. We aimed to assess the ability of COVID-19 screening to detect preprocedural infection at the gastrointestin...

    Authors: Ahmed Eliwa, Osman Mohamed Osman, Ahmed Helal, Abdelgawad Saied Mohamed, Mohammed ElFayoumie, Ramadan Eldamarawy, Sadek Mostafa, Ashraf Elsharkawy, Khaled S. Makboul, Salwa I. Elshennawy, Mahmoud Abdelhady and Ashraf Elbahrawy
    Citation: Egyptian Liver Journal 2022 12:12
    Content type: Original Research Article Published on:

  47. This study aimed to evaluate the efficacy, safety and tolerability of SOF/DCV ± RBV in a cohort of Egyptian patients with chronic hepatitis C (CHC)-induced cirrhosis with decompensation (class B7–B9).

    Authors: Mayssa El Raziky, Sherif Hamdy, Yasser Hamada, Nermin Mohamed Abdelaziz, Mohamed Hassany, Wahid Doss and Zeinab Zakaria
    Citation: Egyptian Liver Journal 2022 12:11
    Content type: Original Research Article Published on:

  48. Osler-Weber-Rendu disease (OWRD) is a rare autosomal dominant genetic disease that causes skin and mucosal telangiectasias and visceral arteriovenous malformations. These shunts can lead to high-output heart f...

    Authors: Oussama Kharmach, Mohamed Borahma, Nawal Lagdali, Imane Benelbarhdadi and Fatima-Zohra Ajana
    Citation: Egyptian Liver Journal 2022 12:10
    Content type: Case report Published on:

  49. The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been predominantly linked to respiratory distress syndrome, but hepatic injury has also been reported. The mecha...

    Authors: Sherine A. Mohammed, Khalid M. Eid, Felix Emeka Anyiam, Hazem Wadaaallah, Muhamed Ahmed Mahmoud Muhamed, Maha Hosni Morsi and Nesrine Ben Hadj Dahman
    Citation: Egyptian Liver Journal 2022 12:9
    Content type: Review Published on:

  50. Gastric antral vascular ectasia (GAVE) is an uncommon but important cause of gastrointestinal bleeding in cirrhotic patients. Argon plasma coagulation (APC) is the standard therapy for GAVE. Endoscopic band li...

    Authors: Mahmoud Abdo, Ahmed Moustafa, Ibrahim Mostafa, Mohammed Salah Abdelbary, Gamaleldin Elatar, Ali Abdel Rahim, Mohamed Abdelhamid and Hanan Abdelhalim
    Citation: Egyptian Liver Journal 2022 12:8
    Content type: Original Research Article Published on:
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  • ISSN: 2090-6226 (electronic)