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Egyptian Liver Journal
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  1. Radiofrequency is one of the curative treatment options for hepatocellular carcinoma (HCC). Despite the progressive improvements in the efficacy of radiofrequency, the survival of patients with HCC who undergo...

    Authors: N. A. Abdelkader, M. H. Abdelaleem, M. A. Abo El-maaty, S. A. Sayed and H. I. Aly
    Citation: Egyptian Liver Journal 2021 11:28
    Content type: Original Research Article Published on:

  2. Gastroesophageal reflux disease (GERD) is one of the most common diseases in modern civilization that originates basically from a disturbance in the structure and function of the lower esophageal sphincter (LE...

    Authors: Taha M. Hassanin, Yasser Foaud, Hala Mohamed, Zienab Saad, Amr Elsayed, Sara Refaei and Wael Soliman
    Citation: Egyptian Liver Journal 2021 11:27
    Content type: Original Research Article Published on:

  3. Cure of chronic hepatitis C (HCV) in HIV/HCV co-infected patients is a priority due to their increased risk of complications. Daclatasvir and sofosbuvir treatment regimens with or without ribavirin are conside...

    Authors: Inas E L-Khedr Mohamed, Kadry Mohamed EL-Saeed, Mahmoud Hassan Al-Sadik and Christina Alphonse Anwar
    Citation: Egyptian Liver Journal 2021 11:26
    Content type: Original Research Article Published on:

  4. The prevention of portal hypertensive complications, including upper gastrointestinal bleeding, is critically important and achieved only through the use of upper endoscopy for the management of oesophageal ga...

    Authors: Yasir M Khayyat
    Citation: Egyptian Liver Journal 2021 11:25
    Content type: Original Research Article Published on:

  5. Acute liver failure (ALF) is a syndromic diagnosis, consisting of jaundice, coagulopathy, and any degree of encephalopathy in a patient without pre-existing liver disease within 26 weeks of the onset of sympto...

    Authors: Akash Roy, Sunil Taneja, Arka De, Ashim Das, Ajay K. Duseja and Virendra Singh
    Citation: Egyptian Liver Journal 2021 11:24
    Content type: Case report Published on:

  6. Accurate assessment of GFR is critical in patients with chronic liver disease for early detection of renal disease. Cystatin C is a marker of GFR that seems to be more accurate than creatinine. The aim of the ...

    Authors: Mona Abd El-Rahman Abu El-Makarem, Mahmoud Mohamed Mousa, Lion Azer Ayaad and Hesham K. H. Keryakos
    Citation: Egyptian Liver Journal 2021 11:23
    Content type: Original Research Article Published on:

  7. Tumor-associated macrophages (TAMs), inflammatory cells in tumor microenvironment, are crucial for the tumor occurrence and progression which in turn increase the expression of soluble CD163 (sCD163). Neverthe...

    Authors: Marwa Ahmed Sakr, Khaled Abdel Hamid Mohamed, Ahmed Mohamed Hussein, Mohamed Hassan Fouad, Ahmed Samir Allam and Eslam Safwat
    Citation: Egyptian Liver Journal 2021 11:22
    Content type: Original Research Article Published on:

  8. Chronic liver diseases are common worldwide, especially in developing countries. The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/(COVID-19) leads to the infection of many patie...

    Authors: Samy Zaky, Mohamed Alboraie, Mohamed El Badry, Mohamed A. Metwally, Ahmed Abdelaziz, Yasser Fouad, Sherief Abd-Elsalam, Abdelmajeed Mahmoud, Gamal Shiha, Amin Abdel Baki, Mohamed El Kassas and Gamal Esmat
    Citation: Egyptian Liver Journal 2021 11:21
    Content type: Review Published on:

  10. Successful eradication of hepatitis C virus (HCV) has great impact on the prognosis of HCV-related complications and the associated mortality. The development of the new direct-acting antiviral drugs (DAAs) ha...

    Authors: Asmaa M. Elbrolosy, Moamena S. Elhamouly, Emad M. Eed, Gamalat A. El Gedawy, Mai Abozeid and Naglaa S. Elabd
    Citation: Egyptian Liver Journal 2021 11:19
    Content type: Original Research Article Published on:

  11. Hepatic encephalopathy exacerbates the morbidity, delays hospital discharge, and increases the rate of readmissions of cirrhotic patients, particularly those are admitted by acute variceal bleeding. We evaluat...

    Authors: Rehab Elsayed Elsafty, Abdallah Ahmed Elsawy, Ahmed Fawzy Selim and Atef Mohamed Taha
    Citation: Egyptian Liver Journal 2021 11:18
    Content type: Original Research Article Published on:

  12. Hepatitis C virus, a silent killer, has infected 71 million people globally. The recombinant viral antigenic proteins might be used in the early diagnosis of HCV infection. The NS3 and NS5A genes of HCV functi...

    Authors: Sabeen Sabri, Muhammad Idrees Khan, Shazia Rafique, Amjad Ali and Muhammad Saleem Khan
    Citation: Egyptian Liver Journal 2021 11:17
    Content type: Original Research Article Published on:

  13. Non-alcoholic fatty liver disease (NAFLD) is the most epidemic liver disorder worldwide as a result of rapid lifestyle transformation over the past few decades and is expected to elevate in the next few years ...

    Authors: Fayed Attia Koutb Megahed, Xiaoling Zhou, Pingnan Sun and Marwa Mohamed Elmaghrabi
    Citation: Egyptian Liver Journal 2021 11:16
    Content type: Review Published on:

  14. Interleukin-4 (IL-4), a pleiotropic anti-inflammatory cytokine, is produced mainly by activated T helper 2 (Th2). Hepatocellular carcinoma (HCC) is a typical inflammation-related cancer. Alterations influencin...

    Authors: Mohy-Eldin Abd-Elfattah, Mary Naguib, Mohammed Elkheer, Eman Abdelsameea and Ali Nada
    Citation: Egyptian Liver Journal 2021 11:15
    Content type: Original Research Article Published on:

  16. Viral resistance-associated substitutions (RASs) can develop in the setting of DAAs therapy (i.e., emerging RASs). Long-term monitoring of fibrosis regression after achieving SVR to simiprevir (SMV)/sofosbuvir...

    Authors: Nahed A. Makhlouf, Mohamed Farouk, Hanan Mohamed Nafeh, Ahmad Farooq Alsayed Hasanain, Mohamed Ahmed El-Mokhtar, Helal F. Hetta, Mohamed A. Mekky, Mohamed Alboraie, Hussein ELamin and Ahmed Medhat Nasr
    Citation: Egyptian Liver Journal 2021 11:13
    Content type: Original Research Article Published on:

  17. Prevalence of hepatitis C virus infection in patients with renal diseases is higher compared to the general population. FDA has approved ombitasvir/paritaprevir/ ritonavir for the treatment of patients with se...

    Authors: Nahla Mohamed Teama, Waleed Anwar Abdel-Mohsen, Ossama Ashraf Ahmed, Sarah Mohamed El Sayed and Ahmed Mohamed ElGhandour
    Citation: Egyptian Liver Journal 2021 11:12
    Content type: Original Research Article Published on:

  18. The global pandemic COVID-19 caused by the new coronavirus SARS-CoV-2 has already caused about 1.4 million deaths, and to date, there are no effective or direct antiviral vaccines. Some vaccines are in the las...

    Authors: Antonio Vitiello, Raffaele La Porta, Vilma D’Aiuto and Francesco Ferrara
    Citation: Egyptian Liver Journal 2021 11:11
    Content type: Review Published on:

  19. Chronic liver disease (CLD) is one of the leading causes of morbidity and mortality in today’s world. Common risk factors for CLD are alcohol, chronic hepatitis B, chronic hepatitis C, non-alcoholic steatohepa...

    Authors: Shashank Banait, Shailesh Mohan Badole, Jyoti Jain and Abasaheb Thorat
    Citation: Egyptian Liver Journal 2021 11:10
    Content type: Original Research Article Published on:

  20. S100A14 is a novel significant individual from S100 proteins family. Its significance is because of its part in tumorigenesis and metastasis process. Elevated level of S100A14 was associated with poor tumor di...

    Authors: Waleed Mohamed Serag and Basem Eysa Elsayed
    Citation: Egyptian Liver Journal 2021 11:9
    Content type: Original Research Article Published on:

  21. The presence of bacteremia as a complication of variceal bleeding in patients with liver cirrhosis had been investigated by many studies. The aim of this study was to assess the bacteremia as a risk factor for...

    Authors: Mohamad Husseini Saeid Zidan, Sahar Gouda Zaghloul, Waseem Mohamed Seleem, Hanan Samir Ahmed and Ahmed Ibrahim Gad
    Citation: Egyptian Liver Journal 2021 11:8
    Content type: Original Research Article Published on:

  22. Helicobacter pylori (HP) infection is considered a risk factor of GIT diseases, e.g., gastric and duodenal ulcers and gastric carcinomas. It is transmitted through feco/oral route and can be diagnosed by many met...

    Authors: Mohamed Rakha, Omayma Saleh, Mohamed S. Abdelgawad and Azza El Baiomy
    Citation: Egyptian Liver Journal 2021 11:7
    Content type: Original Research Article Published on:

  23. Chronic liver disease and cirrhosis are of the major health concern worldwide. Assessment of liver fibrosis is necessary to determine disease severity and prognosis at the time of presentation to determine sui...

    Authors: Heba M. Adel Abou Zaghla, Aziza Ahmed El Sebai, Ossama Ashraf Ahmed, Ayat Fawzy Ahmed and Azza Abdel Rahman Saab
    Citation: Egyptian Liver Journal 2021 11:6
    Content type: Original Research Article Published on:

  24. Hepatocellular carcinoma (HCC) comprises 5.6% of all cancers worldwide representing the sixth most common cancer. It is also the fourth most common cause of cancer-related mortality. Angiogenesis is a main fac...

    Authors: Ahmed Mohamed ElGhandour, Essam Mohamed Bayoumy, Wesam Ahmed Ibrahim, Moataz Mohamed Sayed, Ashraf Bekheet Salama, Nahla Mohamed Teama and Mohamed Magdy Salama
    Citation: Egyptian Liver Journal 2021 11:5
    Content type: Original Research Article Published on:

  25. Insulin-receptor (INSR) is an α2β2 heterotetramer disulfide-linked trans-membrane glycoprotein and a family member of tyrosine kinase receptors. It mediates the pleiotropic actions of insulin regulating glucose h...

    Authors: Rania Nabil Bedair, Gehan M. Magour, Said Ahmed Ooda, Eman M. Amar and Ahmed Mostafa Awad
    Citation: Egyptian Liver Journal 2021 11:4
    Content type: Original Research Article Published on:

  26. HCV is a major risk factor for HCC; however, the exact mechanism of hepatocarcinogenesis is still not fully understood. Host genetic factors have been reported to play a significant role. Experimental studies ...

    Authors: Ghada M. Galal, Ahmad Abudeif, Nagwa Sayed Ahmed, Nahed Fathallah Fahmy, Abeer Sheneef, Elsayed Mostafa Ali, Usama M. Abdelaal and Asmaa Naser Mohammad
    Citation: Egyptian Liver Journal 2021 11:3
    Content type: Original Research Article Published on:

  27. Insulin receptor substrate-1 (IRS1) plays a critical role in insulin signaling. IRS-1 gene polymorphism with glycine to arginine substitution (GGG ↔ AGG substitutions) in codon 972 (G972R) (rs1801278) is a com...

    Authors: Rania Nabil Bedair, Gehan M. Magour, Said Ahmed Ooda, Eman M. Amar and Ahmed M. Awad
    Citation: Egyptian Liver Journal 2021 11:2
    Content type: Original Research Article Published on:

  28. In spite of the huge advances in recent medicine, there is no effective drug that completely protects the liver from toxic materials. This study was conducted to investigate the hepatoprotective effect of arct...

    Authors: Ghalia Mohamed Kanawati, Iqbal Hassan Al-Khateeb and Yasser Ibrahim Kandil
    Citation: Egyptian Liver Journal 2021 11:1
    Content type: Original Research Article Published on:

  29. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ashraf K. Awaad, Maher A. Kamel, Magdy M. Mohamed, Madiha H. Helmy, Magda I. Youssef, Eiman I. Zaki, Marwa M. Essawy and Marwa G. A. Hegazy
    Citation: Egyptian Liver Journal 2020 10:58
    Content type: Correction Published on:

    The original article was published in Egyptian Liver Journal 2020 10:36

  30. The aim of this study was to prospectively evaluate the role of diffusion weight MRI (DWI) in the characterization of hepatic focal lesions by using apparent diffusion coefficient (ADC). Thirty patients (18 wo...

    Authors: Sherif Abugamra, Aya Yassin, Asmaa Saber Mostafa Abdel-Rehim and Dina Sayed Sheha
    Citation: Egyptian Liver Journal 2020 10:57
    Content type: Original Research Article Published on:

  31. Generally, hemangiomas are asymptomatic and most lesions are incidentally diagnosed on abdominal ultrasonography. The indications for surgery are still debated mainly due to limited data about the natural hist...

    Authors: Mohamed M. Mogahed, Ashraf Anas Zytoon, Bassem Essa, Wessam Abdellatif, Nashwa Ghanem and Bahaa ElWakeel
    Citation: Egyptian Liver Journal 2020 10:56
    Content type: Original Research Article Published on:

  32. Hepatocellular carcinoma (HCC) is a prevalent malignancy worldwide. Vitamin D receptor (VDR) gene polymorphisms were linked to different cancers. This study was carried out to assess the possible relation betw...

    Authors: Hala Mosaad, Emad A. Emam, Emad F. Hamed, Ezzat A. El Demerdash and Samia Hussein
    Citation: Egyptian Liver Journal 2020 10:55
    Content type: Original Research Article Published on:

  33. A burden of data suggests that insulin signaling could be impaired with hepatitis C virus infection, and this boost the onset of type 2 diabetes mellitus beyond and in addition to the histological effect on th...

    Authors: Mohamed Mohei El Badry, Doaa Abdelhady Ali, Noha Hamdy Eltaweel and Marwa A. Abdel-Wahed
    Citation: Egyptian Liver Journal 2020 10:54
    Content type: Original Research Article Published on:

  34. To report a case of sudden onset left upper limb monoplegia, convulsions, and bilateral blindness in a patient receiving tacrolimus for immunosuppression following living donor liver transplantation (LDLT) con...

    Authors: Mohamad-Sherif Mogawer, Mostafa EL-Shazly, Ayman Salah, Amany Abdel-Maqsod, Omar Abdelaziz, Ahmed Abdel-Ghani, Mahmoud Essam and Abeer Awad Abdellatif
    Citation: Egyptian Liver Journal 2020 10:53
    Content type: Case report Published on:

  35. Autotaxin (ATX) is an emerging biomarker for liver fibrosis. Achievement of sustained virological response (SVR) by direct-acting antivirals (DAAs) results in hepatic fibrosis regression in chronic hepatitis C...

    Authors: Shereen Abou Bakr Saleh, Khaled Mohamed Abdelwahab, Asmaa Mady Mady and Ghada Abdelrahman Mohamed
    Citation: Egyptian Liver Journal 2020 10:52
    Content type: Original Research Article Published on:

  36. Egypt has the highest hepatitis C virus prevalence worldwide where about 24% of the people are estimated to carry HCV and more than 50% of blood donors have anti-HCV in some towns. The burden of hepatocellular...

    Authors: Ayman Abdelghaffar Eldesoky, Nancy Abdel Fattah Ahmed, Hosam Eldeen Zaghloul and Amr Ahmed Abdel Aziz
    Citation: Egyptian Liver Journal 2020 10:51
    Content type: Original Research Article Published on:

  37. Bile acids are essential organic molecules synthesized from cholesterol in the liver. They have been utilized as indicators of hepatobiliary impairment because synthesis of BAs and their metabolism are influen...

    Authors: Azza Elsheashaey, Manar Obada, Eman Abdelsameea, Mohamed F. F. Bayomy and Hala El-Said
    Citation: Egyptian Liver Journal 2020 10:50
    Content type: Original Research Article Published on:

  38. Being infrequent, drug-induced acute pancreatitis (DIP) is an overlooked clinical entity that can be serious with significant morbidity and mortality.

    Authors: Omkolsoum Alhaddad, Maha Elsabaawy, Marwa Elfauomy, Dalia Elsabaawy and Tarek Mansour
    Citation: Egyptian Liver Journal 2020 10:49
    Content type: Review Published on:

  39. Budd–Chiari syndrome (BCS) is a rare and potentially life-threatening vascular disease of the liver. There are a few studies on the differences between acute and chronic BCS in clinical and laboratory characte...

    Authors: Ramin Niknam, Nemattellah Hajizadegan, Vahid Mohammadkarimi and Laleh Mahmoudi
    Citation: Egyptian Liver Journal 2020 10:48
    Content type: Original Research Article Published on:

  40. Liver transplant population has been considered as a special population in the treatment of hepatitis C virus infection, not only because of lower sustained virological response (SVR) rates in comparison with ...

    Authors: Osama Aboelfotoh Aly, Wael Ahmed Yousry, Nahla Mohamed Teama, Eman Mohammed Shona and Ahmed Mohamed ElGhandour
    Citation: Egyptian Liver Journal 2020 10:47
    Content type: Original Research Article Published on:

  41. Non-alcoholic fatty liver disease (NAFLD) is regarded as the most common liver disease in the twenty-first century, and a condition leaving individuals at increased risk of extra-hepatic morbidity. Liver biops...

    Authors: Ahmed M. F. Mansour, Essam M. Bayoumy, Ahmed M. ElGhandour, Mohamed Darwish El-Talkawy, Sameh M. Badr and Ahmed El-Metwally Ahmed
    Citation: Egyptian Liver Journal 2020 10:33
    Content type: Original Research Article Published on:

  42. Cholestasis is due to the obstruction at any level of the excretory pathway of bile. One particularly troublesome symptom of cholestasis is pruritus which leads to a profound effect on a patient’s quality of l...

    Authors: R. C. Siriwardana, D. S. P. Jayatunge, C. S. Ekanayake, S. Tilakaratne, M. A. Niriella, B. Gunathilake and A. S. Dassanayake
    Citation: Egyptian Liver Journal 2020 10:46
    Content type: Case report Published on:

  43. Deficiency of vitamin D and depression are commonly occurring in patients with chronic liver diseases. This study aimed to determine the association between 25-OH-vitamin D status and depressive symptoms among...

    Authors: Ola G. Behairy, Al Rawhaa A. Abo Amer, Amira I. Mansour and Karim I. Mohamed
    Citation: Egyptian Liver Journal 2020 10:34
    Content type: Original Research Article Published on:

  44. Side effects of antiviral therapies for hepatitis C, especially hematologic abnormalities, may decrease both therapeutic adherence and therapeutic success rate. Adherence to therapy is essential to achieve an ...

    Authors: Sara Abd El Ghany, Noha M. El Husseiny, Mohamed Roshdy, Heba Moustafa, Mohamed Taha Atallah, Ahmed Fathy, Heba H. El Demellawy, Asmaa M. Abdelhameed and Doaa M. El Demerdash
    Citation: Egyptian Liver Journal 2020 10:45
    Content type: Original Research Article Published on:

  46. Hepatitis C virus (HCV) infection is a significant risk factor for cirrhosis and hepatocellular carcinoma (HCC) that carry a high mortality. The study aims to investigate the effect of tumour necrosis factor (...

    Authors: Ahmed Saleh, Ahmed M. Saed and Mostafa Mansour
    Citation: Egyptian Liver Journal 2020 10:43
    Content type: Original Research Article Published on:

  47. Hepatocellular carcinoma (HCC) is one of the commonest malignancies worldwide that carries a bad prognosis particularly in Egypt due to the high prevalence of HCV burden. Late diagnosis of HCC especially in ci...

    Authors: Ahmed Elmetwally Ahmed, Essam Bayoumi, Ahmed E Khayyal, Al Saied Al Refaey and Hagar Elessawy
    Citation: Egyptian Liver Journal 2020 10:42
    Content type: Original Research Article Published on:

  48. Consumption of refined carbohydrates has risen in recent years alongside chronic diseases such as type 2 diabetes mellitus, dyslipidemia, obesity, and non-alcoholic fatty liver disease (NAFLD). Fructose is a m...

    Authors: Gabriel Perri Esteves, Camila Sanches Manca, Hellen Paraguassú Veida-Silva, Paula Payão Ovidio, Héric Holland, Flávia Sayuri Matsuo, Mariana Kiomy Osako and Alceu Afonso Jordao
    Citation: Egyptian Liver Journal 2020 10:35
    Content type: Original Research Article Published on:

  49. Hepatitis C virus (HCV) infection is considered one of the main causes of chronic liver disease around the world. Liver biopsy has been believed to be the gold standard for the assessment of the degree of live...

    Authors: Nancy Abdel Fattah Ahmed, Ahmed Galal Deiab, Ahmad Shawki Mohammad Hasan and Ahmad Mohamed Yousry Abd Elbaky
    Citation: Egyptian Liver Journal 2020 10:41
    Content type: Original Research Article Published on:
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  • ISSN: 2090-6226 (electronic)