Enjoji M, Kotoh K, Kato M et al (2008) Therapeutic effect of ARBs on insulin resistance and liver injury in patients with NAFLD and chronic hepatitis C: a pilot study. Int J Mol Med 22(4):521–527. https://doi.org/10.3892/ijmm_00000051
Article
CAS
PubMed
Google Scholar
Byme CD, Targher G (2015) NAFLD: a multisystem disease. J Hepatol 62(1 Suppl):S47–S64. https://doi.org/10.1016/j.jhep.2014.12.012https://pubmed.ncbi.nlm.nih.gov/?term=Byrne+CD&cauthor_id=25920090
Article
Google Scholar
Mitra S, De A, Chowdhury A (2020) Epidemiology of non-alcoholic and alcoholic fatty liver diseases Transl. Gastroenterol Hepatol 5:16. https://doi.org/10.21037/tgh.2019.09.08
Article
Google Scholar
Younossi Z, Marchesini G, Pinto-Cortez H, Petta S (2019) Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: Implications for Liver Transplantation. Transplantation 103(1):22-27. https://doi.org/10.1097/TP.0000000000002484
Kramer H, Pickhardt PJ, Kliewer MA et al (2017) Accuracy of Liver Fat Quantification With Advanced CT, MRI, and Ultrasound Techniques: Prospective Comparison With MR Spectroscopy. AJR Am J Roentgenol 208(1):92–100. https://doi.org/10.2214/AJR.16.16565
Article
PubMed
Google Scholar
Hernaez R, Lazo M, Bonekamp S et al (2011) Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: a meta-analysis. Hepatology 54(3):1082–1090. https://doi.org/10.1002/hep.24452
Article
PubMed
Google Scholar
Schwimmer JB, Dunn W, Norman GJ et al (2010) SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease. Gastroenterology 138(4):1357–1364. https://doi.org/10.1053/j.gastro.2009.12.052
Article
CAS
PubMed
Google Scholar
Chalasani N, Younossi Z, Lavine JE et al (2012) The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 55:2005–2023. https://doi.org/10.1002/hep.25762
Article
PubMed
Google Scholar
Jung HS, Park KH, Cho YM et al (2006) Resistin is secreted from macrophages in atheromas and promotes atherosclerosis. Cardiovasc Res 69(1):76–85. https://doi.org/10.1016/j.cardiores.2005.09.015
Article
CAS
PubMed
Google Scholar
Efstathiou SP, Tsiakou AG, Tsioulos DI et al (2007) Prognostic significance of plasma resistin levels in patients with atherothrombotic ischemic stroke. Clin Chim Acta 378(1-2):78–85. https://doi.org/10.1016/j.cca.2006.10.023
Article
CAS
PubMed
Google Scholar
Mehta SR, Thomas EL, Patel N et al (2010) Proton magnetic resonance spectroscopy and ultrasound for hepatic fat quantification. Hepatol Res 40(4):399–406. https://doi.org/10.1111/j.1872-034X.2009.00620.x
Article
CAS
PubMed
Google Scholar
Guimaraes GG, Santos SH, Oliveira ML et al (2012) Exercise induces renin-angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice. Peptides 38(1):54–61. https://doi.org/10.1016/j.peptides.2012.05.024
Article
CAS
PubMed
Google Scholar
Michel MC, Brunner HR, Foster C, Huo Y (2016) Angiotensin II type 1 receptor antagonists in animal models of vascular, cardiac, metabolic and renal disease. Pharmacol Ther 164:1–81. https://doi.org/10.1016/j.pharmthera.2016.03.019
Article
CAS
PubMed
Google Scholar
Fang J, Fang D, Silver PB et al (2010) The role of TLR2, TRL3, TRL4, and TRL9 signaling in the pathogenesis of autoimmune disease in a retinal autoimmunity model. Invest Ophthalmol Vis Sci 51(6):3092–3099. https://doi.org/10.1167/iovs.09-4754
Article
PubMed
PubMed Central
Google Scholar
Takeda K, Akira S (2007) Toll-like receptors. Curr Protoc Immunol 14(14):12. https://doi.org/10.1002/0471142735.im1412s109
Article
PubMed
Google Scholar
Kawai T, Akira S (2007) TLR signaling. Semin Immunol 19(1):24–32. https://doi.org/10.1016/j.smim.2006.12.004
Article
CAS
PubMed
Google Scholar
Akashi-Takamura S, Miyake K (2006) Toll-like receptors (TLRs) and immune disorders. J Infect Chemother 12:233–240. https://doi.org/10.1007/s10156-006-0477-4
Article
CAS
PubMed
Google Scholar
Tarkowski A, Bjersing J, Shestakov A, Bokarewa MI (2010) Resistin competes with lipopolysaccharide for binding to toll-like receptor 4. J Cell Mol Med 14(6b):1419–1431. https://doi.org/10.1111/j.1582-4934.2009.00899.x
Article
CAS
PubMed
Google Scholar
Bertolani C, Sancho-Bru P, Failli P et al (2006) Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells. Am J Pathol 169(6):2042–2053. https://doi.org/10.2353/ajpath.2006.060081
Article
CAS
PubMed
PubMed Central
Google Scholar
Holcomb IN, Kabakoff RC, Chan B et al (2000) FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family. Embo j 19(15):4046–4055. https://doi.org/10.1093/emboj/19.15.4046
Article
CAS
PubMed
PubMed Central
Google Scholar
Senolt L, Housa D, Vernerova Z et al (2007) Resistin in rheumatoid arthritis synovial tissue, synovial fluid and serum. Ann Rheum Dis 66(4):458–463. https://doi.org/10.1136/ard.2006.054734
Article
CAS
PubMed
Google Scholar
Axelsson J, Bergsten A, Qureshi AR et al (2006) Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance. Kidney Int 69(3):596–604. https://doi.org/10.1038/sj.ki.5000089
Article
CAS
PubMed
Google Scholar
Yagmur E, Trautwein C, Gressner AM, Tacke F (2006) Resistin serum levels are associated with insulin resistance, disease severity, clinical complications, and prognosis in patients with chronic liver diseases. Am J Gastroenterol 101(6):1244–1252. https://doi.org/10.1111/j.1572-0241.2006.00543.x
Article
CAS
PubMed
Google Scholar
Shiota A, Shimabukuro M, Fukuda D et al (2012) Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice. Cardiovasc Diabetol 11(139). https://doi.org/10.1186/1475-2840-11-139
Mendes KL, Lelis DF, Freitas DF et al (2021) Acute oral treatment with resveratrol and Lactococcus Lactis Subsp. Lactis decrease body weight and improve liver proinflammatory markers in C57BL/6 mice. Mol Biol Rep 48(2):1725–1734. https://doi.org/10.1007/s11033-021-06190-7
Article
CAS
PubMed
Google Scholar
Ribeiro NG, Dos Santos FR, Oliveira JR et al (2021) Hepatotoxic Effect of Lafoensia pacari A. St. Hil. (Lythraceae) on a Diet-Induced Obese Mice Model. Protein Pept Lett 28(7):781–787. https://doi.org/10.2174/0929866528666210127151803
Article
CAS
PubMed
Google Scholar
Hübscher SG (2006) Histological assessment of non-alcoholic fatty liver disease. Histopathology 49(5):450–465. https://doi.org/10.1111/j.1365-2559.2006.02416.x
Article
PubMed
Google Scholar
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25(4):402–408. https://doi.org/10.1006/meth.2001.1262
Article
CAS
PubMed
Google Scholar
Takahashi Y, Sugimoto K, Inui H, Fukusato T (2015) Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 21(13):3777–3785. https://doi.org/10.3748/wjg.v21.i13.3777
Article
CAS
PubMed
PubMed Central
Google Scholar
Gitto S, Vitale G, Villa E, Andreone P (2015) Treatment of nonalcoholic steatohepatitis in adults: present and future. Gastroenterol Res Pract 2015:732870. https://doi.org/10.1155/2015/732870
Article
CAS
PubMed
PubMed Central
Google Scholar
Duseja A, Singh SP, Saraswat VA et al (2015) Non-alcoholic Fatty Liver Disease and Metabolic Syndrome-Position Paper of the Indian National Association for the Study of the Liver, Endocrine Society of India, Indian College of Cardiology and Indian Society of Gastroenterology. J Clin Exp Hepatol 5(1):51–68. https://doi.org/10.1016/j.jceh.2015.02.006
Article
PubMed
PubMed Central
Google Scholar
Oliveira Andrade JM, Paraiso AF, Garcia ZM et al (2014) Cross talk between angiotensin-(1-7)/Mas axis and sirtuins in adipose tissue and metabolism of high-fat feed mice. Peptides 55:158–165. https://doi.org/10.1016/j.peptides.2014.03.006
Article
CAS
PubMed
Google Scholar
Pereira RM, dos Santos RA, da Costa Dias FL, Teixeira MM, Simo Ese Silva AC (2009) Renin-angiotensin system in the pathogenesis of liver fibrosis. World J Gastroenterol 15(21):2579–2586. https://doi.org/10.3748/wjg.15.2579
Article
CAS
PubMed
PubMed Central
Google Scholar
Moreira de Macedo S, Guimaraes TA, Feltenberger JD, Sousa Santos SH (2014) The role of renin-angiotensin system modulation on treatment and prevention of liver diseases. Peptides 62:189–196. https://doi.org/10.1016/j.peptides.2014.10.005
Article
CAS
PubMed
Google Scholar
Koplay M, Sivri M, Erdogan H, Nayman A (2015) Importance of imaging and recent developments in diagnosis of nonalcoholic fatty liver disease. World J Hepatol 7(5):769–776. https://doi.org/10.4254/wjh.v7.i5.769
Article
PubMed
PubMed Central
Google Scholar
Santos SH and Simoes e Silva AC (2014) The therapeutic role of Renin-Angiotensin System blockers in obesity- related renal disorders. Curr Clin Pharmacol 9(1):2-9. https://doi.org/10.2174/15748847112079990050.
Liao AH, Ma WC, Wu MF (2013) Evaluation of ultrasound combined with chitosan for the control of weight and local fat in mice. Ultrasound Med Biol 39(10):1794–1803. https://doi.org/10.1016/j.ultrasmedbio.2013.04.025
Article
PubMed
Google Scholar
Lessa AS, Paredes BD, Dias JV et al (2010) Ultrasound imaging in an experimental model of fatty liver disease and cirrhosis in rats. BMC Vet Res 6:6. https://doi.org/10.1186/1746-6148-6-6
Article
PubMed
PubMed Central
Google Scholar
Kudo H, Yata Y, Takahara T et al (2009) Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue. Liver Int 29(7):988–996. https://doi.org/10.1111/j.1478-3231.2009.02006.x
Article
CAS
PubMed
Google Scholar
Kuk JL, Katzmarzyk PT, Nichaman MZ, Church TS, Blair SN, Ross R (2006) Visceral fat is an independent predictor of all-cause mortality in men. Obesity (Silver Spring) 14(2):336–341. https://doi.org/10.1038/oby.2006.43
Article
Google Scholar
Rocha VZ, Libby P (2009) Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol 6(6):399–409. https://doi.org/10.1038/nrcardio.2009.55
Article
CAS
PubMed
Google Scholar
Santiago NM, Guimaraes PS, Sirvente RA et al (2010) Lifetime overproduction of circulating Angiotensin-(1-7) attenuates deoxycorticosterone acetate-salt hypertension-induced cardiac dysfunction and remodeling. Hypertension 55(4):889–896. https://doi.org/10.1161/HYPERTENSIONAHA.110.149815
Article
CAS
PubMed
Google Scholar
Santos SH, Andrade JM, Fernandes LR et al (2013) Oral Angiotensin-(1-7) prevented obesity and hepatic inflammation by inhibition of resistin/TLR4/MAPK/NF-kappaB in rats fed with high-fat diet. Peptides 46:47–52. https://doi.org/10.1016/j.peptides.2013.05.010
Article
CAS
PubMed
Google Scholar
Miura K, Seki E, Ohnishi H, Brenner DA (2010) Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. Gastroenterol Res Pract 2010:362847. https://doi.org/10.1155/2010/362847
Article
PubMed
Google Scholar
Alqarni I, Bassiouni YA, Badr AM, Ali RA (2019) Telmisartan and/or chlorogenic acid attenuates fructose-induced non- alcoholic fatty liver disease in rats: Implications of cross-talk between angiotensin, the sphingosine kinase/sphingoine-1-phosphate pathway, and TLR4 receptors. Biochem Pharmacol 164:252–262. https://doi.org/10.1016/j.bcp.2019.04.018
Article
CAS
PubMed
Google Scholar
Georgescu EF, Ionescu R, Niculescu M, Mogoanta L, Vancica L (2009) Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis. World J Gastroenterol 15(8):942–954. https://doi.org/10.3748/wjg.15.942
Article
CAS
PubMed
PubMed Central
Google Scholar
Yi ET, Liu RX, Wen Y, Yin CH (2012) Telmisartan attenuates hepatic fibrosis in bile duct-ligated rats. Acta Pharmacol Sin 33(12):1518–1524. https://doi.org/10.1038/aps.2012.115
Article
CAS
PubMed
PubMed Central
Google Scholar
Cynis H, Kehlen A, Haegele M et al (2013) Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice. Int J Exp Pathol 94(3):217–225. https://doi.org/10.1111/iep.12020
Article
CAS
PubMed
PubMed Central
Google Scholar
Nakagami H, Kiomy Osako M, Nakagami F et al (2010) Prevention and regression of non-alcoholic steatohepatitis (NASH) in a rat model by metabosartan, telmisartan. Int J Mol Med 26(4):477–481. https://doi.org/10.3892/ijmm_00000488
Article
CAS
PubMed
Google Scholar
Tamaki Y, Nakade Y, Yamauchi T et al (2013) Angiotensin II type 1 receptor antagonist prevents hepatic carcinoma in rats with nonalcoholic steatohepatitis. J Gastroenterol 48(4):491–503. https://doi.org/10.1007/s00535-012-0651-7
Article
CAS
PubMed
Google Scholar
Mario EG, Santos SH, Ferreira AV, Bader M, Santos RA, Botion LM (2012) Angiotensin-(1-7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes. Peptides 33(1):174–177. https://doi.org/10.1016/j.peptides.2011.11.014
Article
CAS
PubMed
Google Scholar
Ueda S, Masumori-Maemoto S, Ashino K et al (2000) Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man. Hypertension 35(4):998–1001. https://doi.org/10.1161/01.hyp.35.4.998
Article
CAS
PubMed
Google Scholar
Marui N, Offermann MK, Swerlick R et al (1993) Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest 92(4):1866–1874. https://doi.org/10.1172/JCI116778
Article
CAS
PubMed
PubMed Central
Google Scholar