Bertuccio P, Turati F, Carioli G, Rodriguez T et al (2017) Global trends and predictions in hepatocellular carcinoma mortality. J Hepatol 67(2):302–309
Article
PubMed
Google Scholar
Goldman R, Ressom HW, Abd el-hamid M et al (2007) Candidate markers for the detection of hepatocellular carcinoma in low molecular weight fraction of serum. Carcinogenesis 28(10):2149–2153
Article
CAS
PubMed
Google Scholar
Oishi K, Itamoto T, Amano H, Fukuda S et al (2007) Clinico-pathologic features of poorly differentiated hepatocellular carcinoma. J Surg Oncol 95:311–316
Article
PubMed
Google Scholar
Maeda T, Shimada M, Harimoto N, Tsujita E et al (2008) Prognosis of early hepatocellular carcinoma after hepatic resection. Hepatogastroenterology 55:1428–1432
PubMed
Google Scholar
Bruix J, Sherman M (2005) Diagnosis of small HCC. Gastroenterology 129(4):1364
Article
PubMed
Google Scholar
Kawada K, Hasegawa S, Murakami T et al (2011) Molecular mechanisms of liver metastasis. Int J Clin Oncol 16(5):464–472
Article
PubMed
Google Scholar
Dutta R, Mahato RI (2017) Recent advances in hepatocellular carcinoma therapy. Pharmacol Ther 173:106–117
Article
CAS
PubMed
PubMed Central
Google Scholar
Ayuso C, Rimola J, Vilana R, Burrel M et al (2018) Diagnosis and staging of hepatocellular carcinoma (HCC): current guidelines. Eur J Radiol 101:72–81
Article
PubMed
Google Scholar
Soresi M, Terranova A, Licata A, Serruto A, Montalto G, Brancatelli G, Giannitrapani L (2017) Surveillance program for diagnosis of HCC in liver cirrhosis: role of ultrasound echo patterns. Biomed Res Int 2017:4932759
Article
PubMed
PubMed Central
CAS
Google Scholar
Forner A, Reig M, Bruix J (2009) Alpha-fetoprotein for hepatocellular carcinoma diagnosis: the demise of a brilliant star. Gastroenterology 137:26–29
Article
PubMed
Google Scholar
Housset C, Rockey DC, Bissell M (1993) Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin-1. Proc Natl Acad Sci U S A 90:9266–9270
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang R, Dashwood RH (2011) Endothelins and their receptors in cancer: identification of therapeutic targets. Pharmacol Res 63(6):519–524
Article
CAS
PubMed
PubMed Central
Google Scholar
Unic A, Derek L, Hodak N et al (2011) Endothelins-clinical perspectives. Biochem Med 21(3):231–242
Article
CAS
Google Scholar
Notas G, Xidakis C, Valatas V, Kouroumalis A, Kouroumalis E (2001) Levels of circulating endothelin-1 and nitrates/nitrites in patients with virus-related hepatocellular carcinoma. J Viral Hepat 8(1):63–69
Article
CAS
PubMed
Google Scholar
Pinto A, Merino M, Zamora P, Redondo A, Castelo B, Espinosa E (2012) Targeting the endothelin axis in prostate carcinoma. Tumour Biol 33(2):421–426
Article
PubMed
Google Scholar
Rockey DC (2015) Endothelial dysfunction in advanced liver disease. Am J Med Sci 349(1):6–16
Article
PubMed
Google Scholar
Borzacchiello G, Mogavero S, Tortorella G, Catone G, Russo M (2010) Expression of endothelin-1 and endothelin receptor a in canine ovarian tumours. Reprod Domest Anim 45(6):465–468
Article
CAS
Google Scholar
Liakou P, Tepetes K, Germenis A et al (2012) Expression patterns of endothelin-1 and its receptors in colorectal cancer. J Surg Oncol 105(7):643–649
Article
CAS
PubMed
Google Scholar
Irani S, Salajegheh A, Gopalan V, Smith RA, Lam AK (2014) Expression profile of endothelin-1 and its receptor endothelin receptor A in papillary thyroid carcinoma and their correlations with clinic-pathologic characteristics. Ann Diagn Pathol 18(2):43–48
Article
PubMed
Google Scholar
Carducci MA, Jimeno A (2006) Targeting bone metastasis in prostate cancer with endothelin receptor antagonists. Clin Cancer Res 12(20 Pt 2):6296–6300
Article
Google Scholar
Lu JW, Liao CY, Yang WY et al (2014) Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway. PLoS One 9(1):e85318
Article
PubMed
PubMed Central
CAS
Google Scholar
Perkins NJ, Schisterman EF (2005) The Youden index and the optimal cut-point corrected for measurement error. Biom J 47(4):428–441
Article
PubMed
Google Scholar
Forner A, Reig M, Burix J (2018) Hepatocelluler carcinoma. Lancet 391(10127):1301–1314. https://doi.org/10.1016/S0140-6736%20(18)%2030010-2
Article
PubMed
Google Scholar
Yokomori H, Oda M, Yasogawa Y, Nishi Y, Ogi M, Takahashi M, Ishii H (2001) Enhanced expression of endothelin B receptor at protein and gene levels in human cirrhotic liver. Am J Pathol 159(4):1353–1362
Article
CAS
PubMed
PubMed Central
Google Scholar
Helmy A, Jalan R, Newby DE et al (2001) Altered peripheral vascular responses to exogenous and endogenous endothelin-1 in patients with well compensated cirrhosis. Hepatology 33:826–831
Article
CAS
PubMed
Google Scholar
Moore K (2004) Endothelin and vascular function in liver disease. Gut 53:159–161
Article
CAS
PubMed
PubMed Central
Google Scholar
Bauvois B (2012) New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression. Biochim Biophys Acta 1825(1):29–36
CAS
PubMed
Google Scholar
Cong N, Li Z, Shao W, Li J, Yu S (2016) Activation of ETA receptor by endothelin-1 induces hepatocellular carcinoma cell migration and invasion via ERK1/2 and AKT signaling pathways. J Membr Biol 249(1-2):119–128
Article
CAS
PubMed
Google Scholar
Guise TA, Mohammad KS (2004) Endothelins in bone cancer metastases. Cancer Treat Res 118:197–212
Article
CAS
PubMed
Google Scholar
Asham E, Loizidou M, Lakhani S, Miller K, Burnstock G et al (1997) Expression of endothelin-1 in 98 patients with colorectal cancer. Eur J Surg Oncol 23:589
Google Scholar
Rosenblatt R, Valdman A, Cheng L et al (2009) Endothelin-1 expression in prostate cancer and high grade prostatic intraepithelial neoplasia. Anal Quant Cytol Histol 31(3):137–142
PubMed
Google Scholar
Rotondo S, Menard J, Durlach A, Birembaut P, Staerman F (2012) Endothelin-1 and receptor A: predictive value for biochemical relapse on patients with advanced and metastatic prostate cancer. Prog Urol 22:38–44
Article
CAS
PubMed
Google Scholar
Patel KV, Schrey MP (1995) Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts. Br J Cancer 71:442–447
Article
CAS
PubMed
PubMed Central
Google Scholar
Bagnato A, Tecce R, Dicastro V, Catt KJ (1997) Activation of mitogenic signalling by endothelin-1 in ovarian carcinoma cells. Cancer Res 57:1306–1311
CAS
PubMed
Google Scholar
Wu MH, Chen LM, Hsu HH et al (2013) Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma. Biochim Biophys Acta 1830(6):3355–3364
Article
CAS
PubMed
Google Scholar
Uchida Y, Watanabe M (1993) Plasma endothelin-1 concentrations are elevated in acute hepatitis and liver cirrhosis but not in chronic hepatitis. Gastroenterol Jpn 28:666–672
Article
CAS
PubMed
Google Scholar
Matsumoto H, Uemasu J, Kitano M, Kawasaki H (1994) Clinical significance of plasma endothelin-1 in patients with cirrhotic liver disease. Dig Dis Sci 39:2665–2670
Article
CAS
PubMed
Google Scholar
Nakamuta M, Ohashi M, Tabata S et al (1993) High plasma concentrations of endothelin-like immunoreactivities in patients with hepatocellular carcinoma. Am J Gastroenterol 88:248–252
CAS
PubMed
Google Scholar
Gressner AM, Weiskirchen R (2006) Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF beta as major players and therapeutic targets. J Cell Mol Med 10:76–99
Article
CAS
PubMed
Google Scholar
Pfab T, Stoltenburg Didinger G, Trautner C, Godes M, Bauer C, Hocher B (2004) The endothelin system in Morris hepatoma 7777: an endothelin receptor antagonist inhibits growth in vitro and in vivo. Br J Pharmacol 141:215–222
Article
CAS
PubMed
PubMed Central
Google Scholar
Lu JW, Hsia Y, Yang WY, Lin YI, Li CC, Tsai TF, Chang KW et al (2012) Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model. Carcinogenesis 33:209–219
Article
CAS
PubMed
Google Scholar
Li D, Yang P, Li H, Cheng P et al (2012) MicroRNA 1 inhibits proliferation of hepatocarcinoma cells by targeting endothelin 1. Life Sci 91:440–447
Article
CAS
PubMed
Google Scholar
Shi L, Zhou SS, Chen WB, Xu L (2017) Functions of endothelin-1 in apoptosis and migration in hepatocellular carcinoma. Exp Ther Med 13(6):3116–3122
Article
CAS
PubMed
PubMed Central
Google Scholar