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Table 2 Comparison of rotational thromboelastometry (ROTEM) parameters in the study groups

From: The coagulation changes associated with acute variceal bleeding in patients with HCV-induced cirrhosis as assessed by rotational thromboelastometry

Variable

Cirrhotic patients with variceal bleeding (G1) (no. = 60)

Patients with stable cirrhosis (G1) (no. = 60)

p-value

CT (s [median (IQR)]

EXTEM (3879)

56.5 (47.3–74.8)

53.5 (46.3–59.5)

0.23

INTEM (100240)

181 (137.5–225)

174.5 (162.5–205.3)

0.99

CFT (s) [median (IQR)]

EXTEM (34159)

392 (200.5–796)

195 (123–309)

0.01

INTEM (30110)

251 (170–402)

156 (100.5–207)

0.01

α-angle (degree) [mean ± SD]

EXTEM (6383)

52.7 ± 17.4

65.5 ± 9.9

0.01

INTEM (7083)

51.6 ± 14.3

65.8 ± 13

0.01

MCF (mm) [median (IQR)]

EXTEM (5072)

30 (22.5–43)

45 (40–58)

0.002

INTEM (5072)

37.5 (31–46)

47 (40–59)

0.01

FIBTEM (925)

10 (9–13.8)

11.5 (7.3–15.5)

0.45

Clot lysis

A 10 (mm) [mean ± SD]

  EXTEM (4365)

25.1 ± 11.5

39.1 ± 12.7

0.001

  INTEM (4466)

31.7 ± 11.9

43.1 ± 15.3

0.01

  ML (% of MCF) [median (IQR)]

  EXTEM (< 15)

0 (0–0)

0 (0–3.5)

0.32

  INTEM (< 15)

0 (0–0)

0 (0–2)

0.61

  1. Values in the parentheses are normal ranges for ROTEM parameters
  2. Bold values denote statistically significant results
  3. G Group, no. Number, CT Clotting time, CFT Clot formation time, MCF Maximum clot firmness, A 10 Clot amplitude at 10 min, ML Maximum lysis, SD Standard deviation, IQR Interquartile range
  4. Student’s t-test
  5. Mann–Whitney U-test