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Table 1 Baseline characteristics in the study groups

From: The coagulation changes associated with acute variceal bleeding in patients with HCV-induced cirrhosis as assessed by rotational thromboelastometry

Variable

Cirrhotic patients with variceal bleeding (G1) (no. = 60)

Patients with stable cirrhosis (G1) (no. = 60)

p-value

Age (years) [mean ± SD]

52.6 ± 12.1

54.8 ± 9.5

0.53

Gender [no. (%)]

 Male

48 (80)

48 (80)

 Female

12 (20)

12 (20)

 

MELD score [mean ± SD]

14.5 ± 3.2

9.2 ± 2.9

0.001

Hemoglobin (g/dl) [mean ± SD]

9 ± 1.4

12 ± 2

< 0.001

Hematocrit (%) [mean ± SD]

27.5 ± 4.8

40.9 ± 6.5

< 0.001

Platelets (1 × 103/µl) [median (IQR)]

72 (58.3–108.3)

115 (64.3–193)

0.03

Total bilirubin (mg/dl) [mean ± SD]

2.5 ± 1.1

0.9 ± 0.3

< 0.001

ALT (IU/l) [median (IQR)]

79 (52.8–115)

22(17.3–30)

< 0.001

AST (IU/l) [median (IQR)]

93 (46.8–180)

37.5 (23.3–41.5)

< 0.001

Serum albumin (gm/dl) [mean ± SD]

2.9 ± 0.7

4 ± 0.6

< 0.001

INR [median (IQR)]

1.3 (1.2–1.6)

1.2 (1–1.5)

0.049

aPPT (s) [mean ± SD]

45 ± 15

37.9 ± 9.4

0.08

Serum creatinine (mg/dl) [mean ± SD]

1.1 ± 0.4

0.8 ± 0.2

0.008

PVD (mm) [mean ± SD]

14.8 ± 3.9

11 ± 1.4

< 0.001

PSV (cm/s) [mean ± SD]

12 ± 1.4

17 ± 5.3

< 0.001

Grade of EVs [no. (%)]

 0–II

3 (5)

60 (100)

< 0.001

 III–IV

57 (95)

0 (0)

 
  1. Bold values donate statistically significant results
  2. G group, no. Number, MELD Model of end-stage liver disease, ALT Alanine aminotransferase, AST Aspartate transaminase, INR International normalized ratio, aPPT activated partial thromboplastin time, PVD Portal vein diameter, PSV Peak systolic velocity, SD Standard deviation, IQR Interquartile range
  3. Student’s t-test
  4. Mann–Whitney U-test
  5. §χ2 test
  6. Fisher exact test