Table 1 Clinical and laboratory characteristics of the studied groups
HCC, n = 90 | HCV, n = 55 | Con, n = 25 | p < 0.05 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
Age | M ± SD | 58.8 (7.5) | 50.9 (8.) | 51. (7.2) | a | |||||
Sex | Female | 12 (13.3%) | 32 (58.2%) | 13 (52%) | a | |||||
Male | 78 (86.7%) | 23 (41.8%) | 12 (48%) | a | ||||||
BMI | M ± SD | 27.5 (3.6) | 27.3 (3.7) | 27.7 (3.6) | NS | |||||
Liver size | WNS | 73 (81.1%) | 38 (69.1%) | 25 (100%) | ||||||
Enlarged | 13 (14.4%) | 17 (30.9%) | 0.0 (0%) | 0.001 | ||||||
Shrunken | 4 (4.4%) | |||||||||
Splenomegaly | No | 27 (30%) | 31 (56.4%) | 25 (100%) | ||||||
Yes | 63 (70%) | 24 (43.6%) | 0 (0%) | |||||||
Liver cirrhosis | No | 0 (0%) | 7 (12.7%) | 25 (100%) | 0.001 | |||||
Yes | 90 (100%) | 48 (87.3%) | 0 (0%) | |||||||
Ascites | No | 67 (74.4%) | 55 (100%) | 25 (100%) | ||||||
Mild | 17 (18.9%) | |||||||||
Mod | 6 (6.7%) | |||||||||
HFL | Multiple | 52 (57.8%) | 0 (0%) | 0 (0%) | ||||||
Single | 38 (42.2%) | 0 (0%) | 0 (0%) | 0.001 | ||||||
CPC | A | 64 (71.1%) | 40 (72.7%) | |||||||
B | 21 (23.3%) | 11 (20%) | ||||||||
C | 5 (5.6%) | 4 (7.3%) | ||||||||
BCLC | A | 25 (27.8%) | ||||||||
B | 48 (53.3%) | |||||||||
C | 12 (13.3%) | |||||||||
D | 5 (5.6%) | |||||||||
Laboratory | MSD | Min–max | Med (IQR) | Min–max | Med (IQR) | MSD | MSD | Min–max | Med (IQR) | p < 0.05 |
ALT | 59.49 ± 29.15 | 17–168 | 53.5 (23.5) | 12–221 | 37 (46) | 50.49 ± 37.98 | 31.24 ± 23.17 | 10–113 | 23 (26.5) | a, b, c |
AST | 61.80 ± 28.95 | 9–174 | 55.5 (27.5) | 6–166 | 36 (28) | 45.69 ± 29.65 | 31.80 ± 16.09 | 11–64 | 30 (20.5) | a, b, c |
Albumin | 3.61 ± 0.59 | 2.3–4.8 | 3.7 (1) | 3.8–4.8 | 4.1 (0.5) | 4.17 ± 0.29 | 4.26 ± 0.73 | 2.3–5.2 | 4.4 (1) | a, c |
T.Bil | 1.06 ± 0.61 | 0.2–3.2 | 0.9 (0.5025) | 0.3–1.5 | 0.56 (0.28) | 0.61 ± 0.27 | 0.83 ± 0.22 | 0.4–1.2 | 0.9 (0.4) | NS |
D.Bil | 0.45 ± 0.33 | 0.1–2 | 0.38 (0.4) | 0.1–0.9 | 0.2 (0.16) | 0.24 ± 0.15 | 0.14 ± 0.06 | 0.01–0.28 | 0.13 (0.045) | a, b, c |
Creatinine | 0.91 ± 0.21 | 0.4–1.5 | 0.9 (0.2175) | 0.4–1.45 | 0.71 (0.2) | 0.72 ± 0.19 | 1.08 ± 0.38 | 0.6–1.9 | 1.1 (0.605) | b, c |
AFP | 709 ± 3140 | 1.39–27,850 | 86.7 (256.45) | 0.9–182.2 | 3 (3.6) | 11.90 ± 30.95 | 3.28 ± 2.19 | 1.1–11 | 2.9 (1.015) | a, c |
Hb | 13.41 ± 1.74 | 8.7–16.4 | 13.6 (2.4) | 9.3–17.3 | 14 (1.9) | 14.02 ± 1.60 | 12.67 ± 1.47 | 9–15.4 | 13.2 (2.15) | a, b, c |
WBC | 5.78 ± 1.72 | 2–9.6 | 5.35 (2.6) | 3.2–12.7 | 6.6 (3.3) | 7.12 ± 2.08 | 7.55 ± 4.65 | 3.1–19.8 | 6.2 (4.15) | c |
Platelet | 146.93 ± 57.29 | 55–331 | 141 (67.75) | 71–438 | 242 (108) | 235.44 ± 74.29 | 204.44 ± 53.86 | 132–320 | 192 (97.5) | a, c |
PT% | 80.24 ± 12.69 | 36–106 | 82 (14.75) | 57.8–100 | 94 (17) | 90.38 ± 10.70 | 95.76 ± 5.95 | 80–100 | 98 (8) | a, b, c |
INR | 1.19 ± 0.17 | 0.97–1.9 | 1.135 (0.15) | 1–1.39 | 1.04 (0.14) | 1.08 ± 0.10 | 1.08 ± 0.08 | 1–1.3 | 1.06 (0.095) | a, c |