Table 1 Comparison of histopathological findings between infants with BA and infants with non-BA cholestasis
From: Bile duct matrix metalloproteinase-7 expression: a new modality for diagnosis of biliary atresia
Parameter | Biliary atresia N = 25 | Non-biliary atresia N = 25 | χ2 | P value | |
|---|---|---|---|---|---|
Fibrosis stage in biopsy | No fibrosis | 0(0%) | 2(8%) | 11 | 0.012 |
Mild fibrosis | 9(36%) | 18(72%) | |||
Moderate fibrosis | 15(60%) | 5(20%) | |||
Marked fibrosis | 1(4%) | 0(0%) | |||
Infiltrating cells | Chronic inflammatory cells | 6(24%) | 13(52%) | 4.160 | 0.041 |
Mixed inflammatory cells | 19(76%) | 12(48%) | |||
Eosinophils | Present | 2(8%) | 9(36%) | 5.71 | 0.017 |
Absent | 23(92%) | 16(64%) | |||
Intraluminal bile plug | Present | 24(96%) | 7(28%) | 24.53 | < 0.0001 |
Absent | 1(4%) | 18(72%) | |||
Giant cell transformation | Present | 13 (52%) | 12(48%) | 0.080 | 0.777 |
Absent | 12(48%) | 13(52%) | |||