Protective and therapeutic effects of apigenin on thioacetamide-induced hepatotoxicity in male rats: physiological and morphological study

Egyptian Liver Journal

Table 3 Comparison of liver function tests in different studied groups

Groups	AST (U/L)	ALT (U/L)	ALP (U/L)	GGT (U/L)	LDH (U/L)	Total protein (g/L)	Albumin (g/L)	Globulin (g/L)
Control (G1)	21.97±1.50	22.13±1.60	111.40±2.77	7.32±0.77	175.71±10.94	87.82±3.79	14.49±0.74	73.23±4.10
TAA (G2)	217.67±17.90^***	159.66±11.29^***	337.11±20.65^***	54.57±4.91^***	821.14±67.63^***	46.60±5.23^***	4.80±0.62^***	42.266±5.05^***
API (G3)	22.54±1.93^###	26.56±1.79^###	116.26±3.45^###	5.48±0.78^###	179.86±10.75^###	86.14±2.96^###	14.86±0.87^###	71.43±3.17^###
TAA+API (G4)	54.07±5.21^###	42.61±8.06^###	133.32±12.34^###	9.56±0.93^###	272.00±26.00^###	82.57±2.03^###	13.97±0.94^###	68.60±2.01^###
TAA+SL (G5)	24.30±2.02^###	40.12±6.29^###	139.86±16.04^###	8.99±0.67^###	227.71±26.46^###	87.13±3.59^###	16.01±1.05^###	71.12±3.66^###
API+ TAA (G6)	91.19±4.58^***,###	74.75±6.00^***,###	134.88±13.19^###	22.27±3.18^***,###	214.71±19.18^###	83.44±3.77^###	10.91±0.83^###	72.53±4.10^###
SL+ TAA (G7)	88.01±3.97^***,###	55.85±6.87^*,###	114.66±5.85^###	13.18±1.77^###	188.00±9.58^###	86.70±2.09^###	11.71±0.70^###	74.98±2.27^###

^*significance versus control (G1); ^#significance versus TAA (G2); ^*P <0.050 versus control (G1); ^**P <0.010 versus control (G1); ^***P <0.001 versus control (G1); ^#P <0.050 versus TAA (G2); ^##P <0.010 versus TAA (G2); ^###P <0.001 versus TAA (G2)