Protective and therapeutic effects of apigenin on thioacetamide-induced hepatotoxicity in male rats: physiological and morphological study

Egyptian Liver Journal

Table 1 Comparison of body weight and liver weight in different studied groups

Groups	Initial body weights (grams)	Final body weights (grams)	Percentage change in the body weight (%)	Liver weights (grams)	Liver index (%)
Control (G1)	213.14±1.87	223.00±2.06	4.62±0.25	7.79±0.21	3.49±0.09
TAA (G2)	212.29±2.39	202.43±2.45	−4.63±0.84^***	10.49±0.47^*	5.20±0.17^***
API (G3)	218.71±7.74	239.00±3.30^###	9.28±0.65^###	8.95±0.44	3.51±0.16^###
TAA+API (G4)	213.71±4.03	224.29±3.51	5.01±1.04^###	8.75±0.70	3.89±0.29^##
TAA+SL (G5)	220.86±3.60	232.00±3.15^##	5.22±2.25^###	9.22±0.50	4.01±0.18^#
API+ TAA (G6)	229.29±11.75	226.86±11.11^#	−0.97±1.13^*	9.74±0.87	4.33±0.44
SL+ TAA (G7)	216.71±4.19	217.00±5.23	0.11±1.18	9.55±0.47	4.35±0.23

^*significance versus control (G1); ^#significance versus TAA (G2); ^*P <0.050 versus control (G1); ^**P <0.010 versus control (G1); ^***P <0.001 versus control (G1); ^#P <0.050 versus TAA (G2); ^##P <0.010 versus TAA (G2); ^###P <0.001 versus TAA (G2)