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Egyptian Liver Journal

Table 4 QOL (overall and each domain); comparison between adults ≥ 60 years and adults < 60 years old participants

From: Impact of treating chronic hepatitis C with direct acting antivirals on health-related quality of life: a real-life Egyptian experience

Each domain of QOL; comparison between adults ≥ 60 years and adults < 60 years

QOL (adults < 60 years

and adults ≥ 60)

N (%)

Mean QoL score (0–100), SD

Mean difference

P value

Physical health (N = 399)

 Adults < 60 years

211 (53)

76.9, 22.1

3.4

0.13

 Adults ≥ 60 years

188 (47)

73.4, 24.5

  

Emotional health (N = 399)

 Adults < 60 years

211 (53)

85.5, 18.9

2.2

0.2

 Adults ≥ 60 years

188 (47)

83.3, 21.3

  

Future uncertainty (N = 399)

 Adults < 60 years

211 (53)

76.4, 21.4

 − 2.1

0.3

 Adults ≥ 60 years

188 (47)

78.5, 22.3

  

Intimate relation (N = 395)

 Adults < 60 years

211 (53)

85.4, 24.5

 − 6.5

0.003

 Adults ≥ 60 years

184 (47)

92, 18.02

  

Social health (N = 390)

 Adults < 60 years

204 (52)

68.1, 13.6

0.03

0.9

 Adults ≥ 60 years

186 (48)

68.1, 18.3

  

Cognitive function (N = 394)

 Adults < 60 years

209 (52)

86.8, 17.6

 − 2.2

0.2

 Adults ≥ 60 years

185 (48)

89, 22.4

  

Overall QOL; comparison between adults ≥ 60 years and adults < 60 years

Patient characteristics

(N = 381)

N (%)

Mean QoL score (mean = 80.6)

Mean difference

P value

Age

 Adults < 60 years

201 (52)

80.4

 − 0.5

0.7

 Adults ≥ 60 years

180 (48)

80.9

  

Gender

 Male

156 (41)

82.7

3.5

0.01

 Female

225 (59)

79.2, 16.1

  

Comorbidity: hypertension

 No

306 (80)

81.3

3.7

0.04

 Yes

74 (20)

77.6

  

 Missing

1

   

Comorbidity: diabetes

 No

292 (76)

80.6

0.1

0.9

 Yes

88 (24)

80.5

  

 Missing

1

   

Comorbidity: obesity

 No (BMI > 30)

110 (29)

83.1

3.6

0.02

 Yes (BMI < 30)

271 (71)

79.5

  

Cirrhosis

 No (normal + abnormal)

328 (86)

80.4

 − 1

0.6

 Yes

53 (14)

81.4

  

Thrombocytopenia

 No (platelet count > 150)

302 (79)

80.7

0.7

0.6

 Yes (platelet count > 150)

79 (21)

80

  

Alfa Feto-protein

 < 10 ng/mL

302 (80)

80.6

0.6

0.7

 ≥ 10 ng/mL

74 (20)

80.1

  

 Missing

5

   

Liver enzymes: AST

 Normal level (< 40 IU/L)

193 (51)

80.1

 − 1

0.5

 Abnormal level (≥ 40 IU/L)

188 (49)

81.1

  

Liver enzymes: ALT

 Normal level (< 56 IU/L)

272 (71)

79.8

 − 2.8

0.08

 Abnormal level (≥ 56 IU/L)

109 (29)

82.5

  

RBV treatment included

 No

315 (82)

81.3

4

0.03

 Yes

66 (18)

77.3

  
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