Table 2 Baseline demographic, clinical characteristics, and laboratory data of the enrolled patients
Baseline characteristics n = 399 | n, % for categorical values | Mean, SD for continuous variables |
|---|---|---|
Age (years) | Â | 52 (14.5) |
 Adults < 60 | 214 (54) |  |
 Adults ≥ 60 | 185 (46) |  |
Gender | ||
 Male | 163 (41) |  |
 Female | 236 (59) |  |
Comorbidity: hypertension | ||
 No | 223 (82) |  |
 Yes | 73 (18) |  |
 Missing | 1 |  |
Comorbidity: diabetes | ||
 No | 307 (77) |  |
 Yes | 91 (23) |  |
 Missing | 1 |  |
BMI (kg/m2) | Â | 29.8 (6.1) |
 Missing |  | 204 |
Comorbidity: obesity (BMI ≥ 30) | ||
 No | 115 (29) |  |
 Yes | 287 (71) |  |
Smoking status | ||
 Smokers | 50 (17) |  |
 Non-smokers | 242 (83) |  |
 Missing | 105 |  |
Hepatic condition (based on clinician’s decision) | ||
 Normal | 107 (27) |  |
 Abnormal | 230 (598) |  |
 Cirrhotic | 61 (15) |  |
 Missing | 1 |  |
FIB-4 (indicator of cirrhosis) | Â | 2.3 (1.9) |
 < 3.25 (IU) | 316 (79) |  |
 ≥ 3.25 (IU) | 85 (21) |  |
 Missing | 1 |  |
Thrombocytopenia | ||
 No (platelet count × 1000/L ≥ 150) | 317 (79) |  |
 Yes (platelet count × 1000/L < 150) | 85 (21) |  |
HCV serum concentration (IU/mL × 10e + 06) |  | 6.3 [1.6, 20] |
Platelet count (× 109/L) | ||
 Missing |  | 200.8 (69.3) 5 |
Alfa Feto-protein | ||
 < 10 ng/mL | 311 (79) |  |
 ≥ 10 ng/mL | 87 (21) | 7.9 (12.6) |
 Missing | 2 |  |
Liver enzymes: AST | ||
 Normal level (< 40 IU/L) | 204 (51) |  |
 Abnormal level (≥ 40 IU/L) | 195 (49) | 48.4 (31.7) |
Liver enzymes: ALT | ||
 Normal level (< 56 IU/L) | 281 (71) |  |
 Abnormal level (≥ 56 IU/L) | 116 (29) | 49.7 (35.5) |
Treatment status | ||
 Naïve | 374 (94) |  |
 Experienced | 23 (6) |  |
 Missing | 2 |  |
Ribavirin in treatment combination | ||
 No | 322 (81) |  |
 Yes | 75 (19) |  |