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Table 7 Univariate and multivariate logistic regression analysis for the parameters affecting varices (group 2) (nā€‰=ā€‰60 vs. 30)

From: Tissue inhibitor of matrix metalloprotinase-1 and collagen type IV in HCV-associated cirrhosis and grading of esophageal varices

Ā 

Univariate

#Multivariate

P

OR (LLā€“UL 95%C.I)

P

OR (LLā€“UL 95%C.I)

Male

0.881

1.069 (0.444ā€“2.572)

Ā Ā 

Female

0.881

0.935 (0.389ā€“2.250)

Ā Ā 

Age (years)

0.649

1.028 (0.914ā€“1.155)

Ā Ā 

Collagen IV (pg/ml)

<ā€‰0.001*

1.010 (1.006ā€“1.015)

0.007*

1.012 (1.003ā€“1.021)

TIMP (Ī¼g/L)

0.008*

1.037 (1.010ā€“1.065)

0.532

1.017 (0.964ā€“1.074)

Platelets

<ā€‰0.001*

0.932 (0.900ā€“0.966)

Ā Ā 

ALP

0.001*

1.025 (1.010ā€“1.041)

Ā Ā 

ALT

0.041*

1.019 (1.001ā€“1.038)

0.191

0.952 (0.885ā€“1.025)

AST

0.997

1.000 (0.981ā€“1.020)

Ā Ā 

AST/ALT ratio

0.001*

0.350 (0.191ā€“0.640)

0.829

0.786 (0.089ā€“6.945)

Albumin

<ā€‰0.001*

0.047 (0.014ā€“0.151)

0.289

6.141 (0.215ā€“175.677)

Increasing in Child-Pugh classification

<ā€‰0.001*

39.752 (8.329ā€“189.732)

0.080

23.327 (0.684ā€“795.422)

Total bilirubin

0.004*

19.330 (2.588ā€“144.367)

0.561

0.537 (0.066ā€“4.366)

Direct bilirubin

0.003*

28.980 (3.237ā€“259.450)

Ā Ā 

INR$

<ā€‰0.001*

4.958 (2.538ā€“9.685)

0.015*

5.307 (1.380ā€“20.403)

Spleen length

<ā€‰0.001*

11.961 (4.122 ā€“ 34.712)

Ā Ā 

FIB-4 score

0.005*

3.902 (1.521ā€“10.008)

0.458

2.330 (0.249ā€“21.778)

  1. OR oddā€™s ratio, CI confidence interval, LL lower limit, UL upper limit
  2. $: for each 0.1 INR
  3. #: All variables with pā€‰<ā€‰0.05 was included in the multivariate
  4. * Statistically significant at pā€‰ā‰¤ā€‰0.05