Tissue inhibitor of matrix metalloprotinase-1 and collagen type IV in HCV-associated cirrhosis and grading of esophageal varices

Egyptian Liver Journal

Table 6 Diagnostic performance for collagen type IV and TIMP to discriminate patients with varices (n = 60) (group 2) from patients without varices (n = 30) (group 1)

	AUC	P	95% C.I	Cut off	Sensitivity	Specificity	PPV	NPV
Collagen type IV (pg/ml)	0.883	< 0.001^*	0.806–0.960	> 831	86.67	96.67	98.1	78.4
TIMP (μg/L)	0.653	0.019^*	0.538–0.768	> 23	61.67	60.0	75.5	43.9

AUC area under a curve, p value probability value, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
* Statistically significant at p ≤ 0.05