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Table 7 Validity (AUC, sensitivity, specificity) for BDNF to discriminate positive (n = 41) from negative psychometric tests (n = 39)

From: Diagnostic role of serum brain-derived neurotrophic factor in HCV cirrhotic patients with minimal hepatic encephalopathy with and without schistosomiasis

 

AUC

p

95% C.I

Cutoffa

Sensitivity

Specificity

PPV

NPV

BDNF (pg/ml)

0.837

 < 0.001*

0.750 – 0.925

 ≤ 137.88

65.85

84.62

82.0

70.0

  1. AUC Area under a curve; p value Probability value, CI Confidence intervals, NPV Negative predictive value, PPV Positive predictive value
  2. *Statistically significant at p ≤ 0.05
  3. aCutoff was chosen according to the Youden index