| | Statistic | Classic PKU, n = 46 | Atypical PKU, n = 14 | Control, n = 50 | KW P-value |
|---|
Neopterin (nm/L) | M ± SD | 49 ± 13 | 4 ± 1 | 15 ± 3 | |
Min-Max | 20–71 | 3–6 | 8–22 | |
Median (IQR) | 48 (19)a,c | 4 (1)b,c | 16 (6) | < 0.05 |
Biopterin (nm/L) | M ± SD | 50 ± 12 | 3 ± 1 | 15 ± 3 | |
Min-Max | 28–70 | 2–5 | 8–22 | |
Median (IQR) | 48 (20)a,c | 3 (1)b,c | 15 (5) | < 0.05 |
- P-value < 0.05 indicates significance. Mann-Whitney U test comparison between the two groups. P-value < 0.05 indicates a statistically significant difference between the groups
- PKU phenylketonuria, M mean, SD standard deviation, Min minimum, Max maximum, IQR interquartile range, K Kruskal-Wallis test comparison among all groups
- aA significant difference between the healthy control and the classic PKU groups
- bA significant difference between the healthy control and the atypical PKU groups
- cA significant difference between the classical PKU and the atypical PKU groups
