Fig. 1

Expression of PD-L1 clones (22C3 and 28-8) detected by immunohistochemical staining. Representative images of immunohistochemical staining of PD-L1 clones (22C3 and 28-8) in HCC cases. A: Positive strong membranous PD-L1clone 22C3 staining in tumor cells with high PD-L1 expression; B: Negative expression of PD-L1 clone 28-8; C: Negative expression of PD-L1 clone 22C3; D: Positive strong membranous PD-L1clone 28-8 staining in tumor cells; E, F: Positive expression of PD-L1 clones (22C3 and 28-8) in the same tissue specimen. G, H Positive controls (tonsils) for both clones. All images were captured at 40X magnification