Table 1 Comparison of the laboratory test results between the HCC, cirrhosis, and control groups

Hemoglobin (g/dl)

10.08 ± 1.51

9.97 ± 1.04

11.9 ± 0.88

 < 0.001

P1 = 0.799

P2 = 0.002

P3 = 0.042

White blood cells (10⁹/L)

6.94 ± 2.72

5.73 ± 2.07

6.29 ± 0.48

0.096

Platelets (10⁹/L)

102.44 ± 39.97

115.33 ± 33.69

271.2 ± 22.75

 < 0.001

P1 = 0.303

P2 < 0.001

P3 = 0.020

Alanine aminotransferase (IU/L)

76.0 ± 59.36

51.73 ± 23.37

22.1 ± 3.41

0.007

P1 = 0.140

P2 = 0.034

P3 = 0.025

Aspartate aminotransferase (IU/L)

79.84 ± 44.96

88.6 ± 52.56

21.5 ± 3.92

 < 0.001

P1 = 0.579

P2 = 0.042

P3 = 0.027

Alkaline phosphatase (IU/L)

231.6 ± 127.36

264.73 ± 131.14

89.8 ± 17.66

0.002

P1 = 0.436

P2 = 0.024

P3 = 0.012

Gamma Glutamyl transferase (IU/L)

296.04 ± 159.8

79.07 ± 60.29

32.8 ± 9.16

 < 0.001

P1 < 0.001

P2 = 0.027

P3 = 0.012

Total bilirubin (mg/dL)

2.85 ± 1.86

1.94 ± 0.89

0.8 ± 0.27

 < 0.001

P1 = 0.085

P2 = 0.032

P3 = 0.026

Direct bilirubin (mg/dL)

1.38 ± 1.08

0.85 ± 0.58

0.16 ± 0.11

 < 0.001

P1 = 0.087

P2 = 0.021

P3 = 0.035

Serum albumin (g/dL)

2.78 ± 0.75

3.1 ± 0.61

4.4 ± 0.64

 < 0.001

P1 = 0.172

P2 < 0.001

P3 = 0.053

Prothrombin time (sec)

17.76 ± 5.84

17.03 ± 2.99

13.9 ± 1.85

0.085

Alpha fetoprotein (ng/mL)

234.32 ± 108.06

24.20 ± 10.54

6.35 ± 1.24

 < 0.001

P1 < 0.001

P2 < 0.001

P3 > 0.050

Thioredoxin (ng/mL)

140.96 ± 12.70

88.33 ± 10.34

73.10 ± 13.22

 < 0.001

P1 < 0.001

P2 < 0.001

P3 < 0.050