Table 3 Frequency of abnormalities observed in Alagille syndrome [6]
| Â | Emerick 1999 | Alagille 1987 | Deprettere 1987 |
|---|---|---|---|
Bile duct paucity | 85% | 100% | 81% |
Chronic cholestasis | 96% | 91% | 93% |
Cardiac murmur | 97% | 85% | 96% |
Vertebral anomalies | 51% | 87% | 33% |
Facies | 96% | 95% | 70% |
Eye findings | 78% | 88% | 56% |
Renal disease | 40% | 73% | – |
Minor features | Â | Â | Â |
 Growth retardation | 87% | 50% | 73% |
 Mental retardation | 2% | 16% | 0% |
 Developmental delay | 16% | – | 52% |
 Pancreatic insufficiency | 41% | – | – |