Table 4 Comparison between CKD and non-CKD subjects with NAFLD (N = 215)

Sociodemographic

Age (y)

Mean ± SD

52.9 ± 10.6

51.1 ± 12.0

0.265*

Sex

Male

Female

32 (39%)

50 (61%)

60 (45.1%)

73 (54.9%)

0.381^#

Comorbidities

BMI (kg/m²)

Mean ± SD

33.6 ± 6.0

31.1 ± 3.9

 < 0.001*

Waist circumference (cm)

Mean ± SD

98.8 ± 15.2

79.5 ± 13.3

0.530*

DM

Yes

No

47 (57.3%)

35 (42.7%)

26 (19.5%)

107 (80.5%)

 < 0.001^#

Hypertension

Yes

No

55 (67.1%)

27 (32.9%)

73 (54.9%)

60 (45.1%)

0.077^#

Metabolic syndrome

Yes

No

44 (53.7%)

38 (46.3%)

34 (25.6%)

99 (74.4%)

 < 0.001^#

Laboratory investigations

CBC

TLC (10*3/Ul)

8.0 ± 2.5

6.9 ± 2.3

0.001*

Hb

10.6 ± 1.4

10.8 ± 1.7

0.306*

PLts

271.6 ± 96.4

255.4 ± 99.6

0.243^$

KFT

Creatinine (mg/dl)

2.3 ± 1.9

0.8 ± 0.1

 < 0.001^$

Urea (mg/dl)

61.2 ± 44.8

37.2 ± 10.4

 < 0.001^$

Uric acid (mg/dl)

5.6 ± 1.7

5.1 ± 1.2

0.007*

ACR (mg/gm)

117.7 ± 150.0

4.2 ± 7.2

 < 0.001^$

eGFR

50.9 ± 38.7

97.8 ± 28.3

 < 0.001^$

Albuminuria Abnormal Normal

53 (64.6%)

29 (35.4%)

0

133 (100%)

 < 0.001^#

LFT

AST

39.7 ± 26.3

38.0 ± 22.9

0.622^$

ALT

31.3 ± 15.5

29.8 ± 17.3

0.530^$

T. bilirubin

0.56 ± 0.29

0.60 ± 0.33

0.382^$

Albumin

3.5 ± 0.6

3.8 ± 0.5

 < 0.001*

Prothrombin activity

75.8 ± 12.2

75.0 ± 10.6

0.603*

Lipid profile

Total cholesterol

237.7 ± 139.8

206.4 ± 53.5

0.021*

Triglycerides

195.7 ± 73.7

192.8 ± 122.3

0.845^$

LDL

115.1 ± 40.3

109.8 ± 40.8

0.355*

HDL

38.8 ± 13.4

42.2 ± 10.6

0.041*

FBS

115.3 ± 44.9

93.6 ± 21.2

 < 0.001*

LDH

212.3 ± 64.3

196.2 ± 49.0

0.039*

NFS score

-0.29 ± 2.1

-1.17 ± 1.7

0.001*

FIB-4 score

1.6 ± 1.3

1.5 ± 0.9

0.509*