Table 1 Basic and laboratory characteristics of the NAFLD and non-NAFLD groups (N = 340)

Age (Y)

Mean ± SD

51.8 ± 11.5

53.5 ± 9.2

0.128*

Sex

Male

Female

92 (42.8%)

123 (57.2%)

106 (49.3%)

109 (50.7%)

0.176^#

BMI (kg/m²)

Mean ± SD

32.1 ± 5.0

27.7 ± 2.0

 < 0.001*

Waist circumference (cm)

Mean ± SD

98.0 ± 14.1

84.7 ± 8.5

 < 0.001*

DM

Yes

No

73 (34%)

142 (66%)

41 (19.1%)

174 (80.9%)

 < 0.001^#

Hypertension

Yes

No

128 (59.5%)

87 (40.5%)

70 (32.6%)

145 (67.4%)

 < 0.001^#

Metabolic syndrome

Yes

No

78 (36.3%)

137 (63.7%)

16 (7.4%)

199 (92.6%)

 < 0.001^#

CKD

Yes

No

82 (38.1%)

133 (61.9%)

16 (7.4%)

199 (92.6%)

 < 0.001^#

Laboratory investigations

CBC

TLC (10*3/Ul)

7.3 ± 2.4

6.9 ± 2.0

0.060*

Hb

10.7 ± 1.6

11.0 ± 1.5

0.120*

PLts

261.6 ± 98.5

248 (187 – 330)

241.7 ± 93.3

224 (169 – 300)

0.032^$

KFT

Creatinine (mg/dl)

1.35 ± 1.37

0.8 (0.7 – 1.1)

0.72 ± 0.19

0.8 (0.6 – 0.8)

 < 0.001^$

Urea (mg/dl)

46.4 ± 31.0

36 (33 – 43)

36.2 ± 20.1

33 (26 – 38)

 < 0.001^$

Uric acid (mg/dl)

5.3 ± 1.4

0.7 ± 0.2

 < 0.001*

ACR (mg/gm)

45.5 ± 95.4

12.0 ± 18.7

0.001^$

eGFR (ml/min/1.73 m²)

79.9 ± 39.8

80.4 (58.8 – 104.5)

117.4 ± 48.7

105.5 (81.6 – 130.4)

 < 0.001^$

Albuminuria Abnormal Normal

53 (24.7%)

162 (75.3%)

15 (7%)

200 (93%)

 < 0.001^#

LFT

AST

38.6 ± 24.2

40 (19 – 56)

27.0 ± 11.9

25 (19 – 34)

 < 0.001^$

ALT

30.4 ± 16.6

31 (15 – 42)

22.3 ± 15.6

19 (13 – 28)

 < 0.001^$

T bilirubin

0.58 ± 0.31

0.6 (0.3 – 0.8)

0.63 ± 0.42

0.6 (0.3 – 0.9)

0.189^$

Albumin

3.7 ± 0.6

3.9 ± 0.4

 < 0.001*

Prothrombin activity

75.3 ± 11.2

87.3 ± 9.2

 < 0.001*

Lipid profile

Total cholesterol

218.3 ± 96.9

175.5 ± 46.6

 < 0.001*

Triglycerides

193.9 ± 106.2

170 (130 – 221)

157.1 ± 61.9

178 (99 – 200)

 < 0.001^$

LDL

111.8 ± 40.6

96.5 ± 31.5

 < 0.001*

HDL

40.9 ± 11.8

51.5 ± 16.5

 < 0.001*

FBS

101.9 ± 33.9

87.1 ± 14.6

 < 0.001*

LDH

202.3 ± 55.7

190.7 ± 31.6

0.008*