Table 1 Studied BDNF polymorphisms
From: Relationship between BDNF gene polymorphisms and alcohol-related liver cirrhosis
SNP (major/minor alleles) | Position (GRCh38.p13) | HardyāWeinberg equilibrium Ļ2 (p) | Reported MAF (1000 Genomes Project) | Observed MAF | |
|---|---|---|---|---|---|
AUD, n = 71 | ALC, n = 110 | ||||
rs925946 (G/T) | chr11:27645655, 3ā²-UTR (reverse strand) | 0.325 (0.850) | 3.369 (0.186) | 0.253 | 0.243 |
rs6265 (G/A) | chr11:27658369, Exon ā missense | 1.380 (0.502) | 0.870 (0.647) | 0.201 | 0.146 |
rs10835210 (C/A) | chr11:27674363, Intron | 0.077 (0.963) | 1.750 (0.417) | 0.245 | 0.450 |
rs7103411 (T/C) | chr11:27678578, Intron | 2.386 (0.303) | 3.937 (0.140) | 0.247 | 0.157 |
rs75945125 (T/C) | chr11:27757378, 5ā²-UTR (reverse strand) | 0.138 (0.933) | 0.366 (0.833) | 0.104 | 0.050 |