Variables | Total (N = 57) | Cirrhotic PH (N = 13) | Non-cirrhotic PH (N = 44) | P-value |
---|---|---|---|---|
Gender, male, n (%) | 39 (68.40) | 10 (76.90) | 29 (65.9) | 0.45 |
Mean age ± SD (years) | 40.02 ± 12.32 | 50.23 ± 11.50 | 37.00 ± 10.94 | < 0.001 |
Hypertension, yes/no | 7/50 | 2/11 | 5/39 | 0.70 |
Diabetes, yes/no | 3/54 | 1/12 | 2/42 | 0.65 |
Number of previous bleeds, mean ± SD | 2.88 ± 2.56 | 3.23 ± 2.00 | 2.77 ± 2.71 | 0.58 |
1/2/ ≥ 2 | 9/21/22 | 0/7/6 | 9/14/16 | 0.276 |
Jaundice, yes/no | 17/40 | 9/4 | 8/36 | < 0.001 |
Splenomegaly, yes/no | 37/20 | 5/8 | 32/12 | 0.02 |
Stage 1/2/3/4/5 | 1/13/11/7/5 | 1/4/0/0/0 | 0/9/11/7/5 | 0.016 |
Ascites, yes/no | 14/43 | 5/8 | 9/35 | 0.19 |
Grade 1/2/3 | 3/5/6 | 1/1/3 | 2/4/3 | 0.37 |
Causes of cirrhotic PH, n (%) | ||||
Alcohol | 5 (8.80) | 5 (38.46) | - | - |
Hepatitis B virus | 4 (7.00) | 4 (30.77) | - | - |
Hepatitis C virus | 1 (1.80) | 1 (7.69) | - | - |
Alcohol/hepatitis B virus | 1 (1.80) | 1 (7.69) | - | - |
Autoimmune hepatitis | 2 (3.50) | 2 (15.39) | - | - |
Causes of non-cirrhotic PH, n (%) | ||||
Hepatosplenic schistosomiasis | 40 (70.20) | - | 40 (90.91) | - |
Portal thrombosis | 4 (7.00) | - | 4 (9.09) | - |
Grade of esophageal varix III/II | 55/2 | 13/0 | 42/2 | 0.43 |
Red signs, yes/no | 22/35 | 5/8 | 17/27 | 0.99 |
Child–Pugh score, mean ± SD | 8.38 ± 2.29 | 8.38 ± 2.29 | - | - |
Child–Pugh class, A/B/C | 3/8/2 | 3/8/2 | - | - |
Dose de propranolol (mg/jour), mean ± SD | 108.07 ± 38.52 | 86.15 ± 22.19 | 114.55 ± 40.08 | 0.02 |
Propranolol dose (mg/day), 80/160 | 37/20 | 12/1 | 25/19 | 0.02 |
Indication for EVL, n (%) | ||||
Primary prevention | 3 (5.30) | 0 (0.00) | 3 (6.80) | 0.33 |
Secondary prevention | 54 (94.70) | 13 (100.00) | 41 (93.20) | |
Number of sessions, mean ± SD | 2.40 ± 1.03 | 2.31 ± 1.03 | 2.43 ± 1.04 | 0.71 |
Time between EVL sessions (months), mean ± SD | 1.30 ± 0.46 | 1.31 ± 0.48 | 1.30 ± 0.46 | 0.93 |
Follow-up time (months), mean ± SD | 6.28 ± 6.54 | 7.69 ± 7.27 | 5.86 ± 6.33 | 0.38 |