Table 4 Per protocol and intention to treat analysis for the treatment groups

Item

Standard therapy

Probiotic therapy

Odd ratio (95% CI)

P value

Patients randomized

59

100

Patients lost to follow-up

4

5

Patients followed up

55

95

Patients with H. pylori eradication

42

78

Patients resist H. pylori eradication

17

22

Intention to treat analysis

71.19% (42/59)

78.00% (78/100)

0.69 (0.33–1.45)

0.335

Per-protocol analysis

69.09% (38/55)

76.84% (73/95)

0.79 (0.51–1.22)

0.297

Standard therapy

Probiotics before standard therapy

Odd ratio (95% CI)

P value

Patients randomized

59

42

Patients lost to follow-up

4

2

Patients followed up

55

40

Patients with H. pylori eradication

42

31

Patients resist H. pylori eradication

17

11

Intention to treat analysis

71.19% (42/59)

73.81% (31/42)

0.87 (0.36–2.13)

0.772

Per-protocol analysis

69.09% (38/55)

72.50% (29/40)

0.85 (0.34–2.08)

0.719

Standard therapy

Probiotic after standard therapy

Odd ratio (95% CI)

P value

Patients randomized

59

58

Patients lost to follow-up

4

3

Patients followed up

55

55

Patients with H. pylori eradication

42

47

Patients resist H. pylori eradication

17

11

Intention to treat analysis

71.19% (42/59)

81.04% (47/58)

0.58 (0.24–1.37)

0.021*

Per-protocol analysis

69.09% (38/55)

80.00% (44/55)

0.53 (0.27–1.30)

0.018*

Probiotics before standard therapy

Probiotic after standard therapy

Odd ratio (95% CI)

P value

Patients randomized

42

58

Patients lost to follow-up

2

3

Patients followed up

40

55

Patients with H. pylori eradication

31

47

Patients resist H. pylori eradication

11

11

Intention to treat analysis

73.81% (31/42)

81.04% (47/58)

0.66 (0.26 – 1.70)

0.389

Per-protocol analysis

72.50% (29/40)

80.00% (44/55)

1.52 (0.58 – 3.95)

0.392