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Table 1 Table showing the initial and final weight, percentage change in weight and blood glucose levels of mice exposed to Artemether/lumefantrine (A/L) and artesunate/amodiaquine (A/A) compared to the control (CTL)

From: Baseline and recurrent exposure to the standard dose of artemisinin-based combination therapies (ACTs) induces oxidative stress and liver damage in mice (BALB/c)

Exposure periods

Treatment

Initial body Weight (g)

Final body weight (g)

Percentage change in body weight (%)

Blood glucose level

First

CTL

23.57 ± 0.28

25.53 ± 0.38

8.39 ± 2.39

7.49 ± 0.41

A/L

24.73 ± 0.38

25.50 ± 0.26

3.18 ± 2.62

9.09 ± 0.27

A/A

22.83 ± 0.41

25.87 ± 0.39

13.38 ± 3.07

7.43 ± 0.04

Second

CTL

24.53 ± 0.33

26.77 ± 0.18

9.14 ± 1.68

7.33 ± 0.32

A/L

25.30 ± 0.25

26.80 ± 0.17

5.95 ± 1.32

8.11 ± 0.02

A/A

24.47 ± 0.35

26.90 ± 0.29

9.98 ± 1.66

8.35 ± 0.00

Third

CTL

25.30 ± 0.25

30.10 ± 1.04

18.92 ± 3.01

7.91 ± 0.09

A/L

23.60 ± 1.15

29.70 ± 0.17

25.87 ± 1.44

8.21 ± 0.08

A/A

24.47 ± 0.38

29.53 ± 0.32

20.73 ± 0.58

8.25 ± 0.10

Sixth

CTL

25.27 ± 0.27

31.60 ± 0.83

29.22 ± 4.14

8.39 ± 0.61

A/L

24.63 ± 0.24

33.07 ± 0.26

30.88 ± 0.59

7.68 ± 0.14

A/A

23.97 ± 0.41

32.43 ± 0.32

35.38 ± 1.84

8.70 ± 0.08