Table 1 Characteristics of 134 cases of BD-IPMN as described in the clinical report
Factors | All patients N = 134 | With progression of lesions N = 6 | Without progression of lesions N = 128 | P |
|---|---|---|---|---|
Sex, male:female | 67:67 | 3:3 | 64:64 | 1.00 |
Age, median (range), years | 68 (44–83) | 72 (59–80) | 67.5 (44–83) | 0.26 |
Diabetes mellitus at the initial diagnosis, n (%) | 21 (15.7) | 1 (16.7) | 20 (15.6) | 0.95 |
Follow-up period, median (range), months | 35.8 (12.1–157) | 18.4 (14.2–31.0) | 36.9 (12.1–157) | 0.0065 |
Number of multifocal IPMNs (multifocal/unifocal), n (%) | 53 (39.6) | 3 (50.0) | 50 (39.1) | 0.59 |
CEA, median (range), ng/ml | 2.0 (0.2–11.2) | 2.9 (1.5–7.2) | 2.0 (0.2–11.2) | 0.25 |
CA19-9, median (range), U/ml | 10.3 (0.1–253.3) | 16.0 (9.0–32.0) | 9.85 (0.1–253.3) | 0.12 |
Size of MPD at the initial diagnosis, median (range), mm | 2.4 (1.0–9.0) | 2.0 (1.2–6.0) | 2.4 (1.0–9.0) | 0.69 |
Size of cyst at the initial diagnosis, median (range), mm | 16 (1.7–48.0) | 22.5 (10.3–37.8 | 15.7 (1.7–48.0) | 0.17 |
Presence of mural nodule at the initial diagnosis, n (%) | 5 (3.7) | 0 | 5 (3.9) | 0.59 |
Invasive carcinoma derived from IPMN, n (%) | 2 (1.5) | 2 (33.3) | 0 |  < 0.0001 |
Surgical resection of IPMN, n (%) | 5 (3.7) | 2 (33.3) | 3 (2.3) |  < 0.0001 |
Surgery for malignancy of other organs, n (%) | 18 (13.4) | 3 (50.0) | 15 (11.7) | 0.0072 |
Surgery for benign lesion of other organs, n (%) | 7 (5.2) | 0 | 7 (5.5) | 0.56 |
Surgery for benign lesion of other organs, n (%) | 5 (3.7) | 0 | 5 (3.9) | 0.62 |