Study of transcription factor 7-like 2 (TCF7L2) gene polymorphism in cirrhotic patients with diabetes

Egyptian Liver Journal

Table 2 TCF7L2 genotyping and allele distribution of the studied groups

TCF7L2	Control (n = 25)		Cirrhosis (n = 25)		DM (n = 25)		Cirrhotic diabetic (n = 25)		χ²	P
TCF7L2	No	%	No	%	No	%	No	%	χ²	P
Genotypes
CC®	11	44.0	10	40.0	4	16.0	3	12.0	12.249^*	^MCp = 0.045^*
CT	13	52.0	14	56.0	16	64.0	18	72.0
TT	1	4.0	1	4.0	5	20.0	4	16.0
Dominant model
CC®	11	44.0	10	40.0	4	16.0	3	12.0	9.921	^MCp = 0.019^*
CT + TT	14	56.0	15	60.0	21	84.0	22	88.0	9.921	^MCp = 0.019^*
Recessive model
CC + CT	24	96.0	24	96.0	20	80.0	21	84.0	4.829	^MCp = 0.234
TT	1	4.0	1	4.0	5	20.0	4	16.0	4.829	^MCp = 0.234
Alleles
C®	35	70.0	34	68.0	24	48.0	24	48.0	9.124^*	0.028^*
T	15	30.0	16	32.0	26	52.0	26	52.0	9.124^*	0.028^*

χ² Chi-square test, MC Monte Carlo, p p value for comparing between the studied groups
^*Statistically significant at p ≤ 0.05