Table 3 The Fold change of BAX and BCL-2 mRNA expression as revealed by qRT-PCR of hepatocytes of control and treated male albino mice (Mus musculus)
From: Genotoxic effect of Tamiflu and Adamine on DNA content in male albino mice
Animal group | Fold change | Mean of Δ ct ± SD | ||
|---|---|---|---|---|
BAX | BCL-2 | BAX | BCL-2 | |
C-group | 1 | 1 | 4.47 ± 0.75 | 9.58 ± 0.96 |
T5 | 0.44↓ | 9.98↑ | 5.67 ± 1.85 | 6.26 ± 2.92 |
T10 | 0.35↓ | 2.67↑ | 5.97 ± 0.52* | 8.16 ± 0.67 |
T15 | 2.19↑ | 3.47↑ | 3.34 ± 0.86 | 7.79 ± 3.26 |
A5 | 0.74↓ | 0.70↓ | 3.94 ± 1.68 | 10.09 ± 12.36 |
A10 | 2.85↑ | 7.84↑ | 2.96 ± 0.35* | 6.61 ± 0.71* |
A15 | 2.12↑ | 3.04↑ | 3.39 ± 0.52 | 7.97 ± 0.96 |
TA5 | 1.07↑ | 5.01↑ | 4.38 ± 0.87 | 7.25 ± 2.31 |
TA10 | 0.68↓ | 8.13↑ | 5.03 ± 0.89 | 6.56 ± 2 |
TA15 | 0.82↓ | 10.32↑ | 4.76 ± 0.6 | 6.21 ± 1.64* |