Table 1 Case reports until date of terlipressin-induced ischemic events
From: The “dark” side of terlipressin: a case report of ischemic skin necrosis and review of literature
S. no | Authors | Age | Sex | Etiology | Risk factors | Indication | Dose | MELD | Outcome |
|---|---|---|---|---|---|---|---|---|---|
1 | Iglesias Julian et al. (2017) [7] | 84 | F | HCV | HTN, CRF | Variceal bleed | Bolus | 28 | Survived |
2 | Sarma et al. (2017) [8] | 65 | M | Ethanol | Diabetes | Variceal bleed | Bolus | - | Died |
3 | Ozel Coskun et al. (2014) [9] | 65 | M | NASH | Obesity/ischemic heart disease/HTN | Variceal bleed | Bolus | 10 | Survived |
4 | Sundriyal et al. (2013) [10] | 47 | M | Ethanol | NA | Variceal bleed | Bolus | - | - |
5 | Yefet et al. (2011) [11] | 66 | M | Ethanol | Obesity, ischemic heart disease, diabetes | Variceal bleed | Bolus | - | Died |
6 | Bañuelos Ramírez et al. (2017) [12] | 51 | F | Ethanol | Chronic kidney disease | Variceal bleed | Bolus | - | Survived |
7 | Elzouki et al. (2010) [13] | 52 | M | Cryptogenic | Diabetes, hypothyroidism | Variceal bleed | Bolus | 12 | Survived |
8 | Kumar N. et al. (2020) [14] | 57 | F | Ethanol | Variceal bleed | Bolus | - | Survived | |
9 | Chandail VS et al. (2011) [15] | 47 53 41 | M F M | 1. Cryptogenic 2. NASH 3. Ethanol | Obesity Obesity - | Hepatorenal syndrome Hepatorenal syndrome Variceal bleed | Bolus - Bolus | Died Died Survived | |
10 | Donnellan et al. (2007) [16] | 47 53 56 | M F M | 1. AIH 2. NASH 3. Ethanol | Venous insufficiency - - | Hepatorenal syndrome Hepatorenal syndrome Variceal bleed | Bolus + octreotide | 24 23 9 | Died Died Died |
11 | Simões Macedo S et al. (2019) [17] | 71 | M | NASH | - | Hepatorenal syndrome + variceal bleed | Bolus | - | Died |
12 | Cleva R. D. et al. (2016) [18] | 47 68 | M M | Ethanol | - - | Variceal bleed Hepatorenal syndrome | Bolus Bolus | - - | Survived Died |
13 | Chiang et al. (2019) [19] | 65 | M | Ethanol | HTN | Hepatorenal syndrome | Bolus | 28 | Survived |
14 | Herrera et al. (2015) [20] | 55 | M | Ethanol | ICH | Hepatorenal syndrome | Bolus | 29 | Died |
15 | Lee and Oh (2013) [21] | 71 | M | Ethanol + chronic hepatitis C | Prior pulmonary TB | Hepatorenal syndrome | Bolus | 25 | Survived |
16 | Taşliyurt et al. (2012) [22] | 79 65 | M M | 1. Ethanol 2. Hepatitis B | - | Hepatorenal syndrome | Bolus | - | Died |
17 | Sahu et al. (2010) [23] | 50 | M | Ethanol | Diabetes | Hepatorenal syndrome | Bolus | - | Died |
18 | Posada et al. (2009) [24] | 39 | M | Ethanol | - | Hepatorenal syndrome | Bolus | - | Died |
19 | Mégarbané et al. (2009) [25] | 68 74 | M M | 1. Ethanol/HCC 2. Adenocarcinoma | Diabetes, ischemic heart disease, dyslipidemia | Hepatorenal syndrome Pseudo-hepatorenal syndrome | Bolus Infusion | - - | Died Died |
20 | Di Micoli et al. (2008) [26] | 65 | F | HCC, hepatitis C | Hypothyroidism | Hepatorenal syndrome | Bolus + infusion | 15 | Survived |
21 | |||||||||
22 | Lee et al. (2006) [27] | 41 | M | Etiology | - | Hepatorenal syndrome | Bolus | 30 | - |
23 | Vaccaro et al. (2003) [28] | 73 | M | HCV | - | Hepatorenal syndrome | Bolus | 28 | Died |
24 | Karakus V. et al. (2019) [29] | 67 | M | Ethanol | HTN | Hepatorenal syndrome | Bolus | 30 | Died |
25 | Ahmed R. et al. (2018) [30] | 50 | F | Ethanol | HTN | Hepatorenal syndrome | Bolus | 36 | Died |
26 | Jain G. et al. (2021) [31] | 54 | M | Cryptogenic | Hepatorenal syndrome | Bolus | - | - | |
27 | Our patient | 45 | M | Ethanol | - | Variceal bleed | Bolus | - | Died |