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Table 1 Comparison between the three studied groups according to demographic data and laboratory data

From: Liver stiffness, hepatorenal index, and microRNA-130b as predictors for chronic kidney disease in patients with non-alcoholic fatty liver disease

Demographic data

Group I (n = 20)

Group II (n = 20)

Group (n = 20)

p

Gender

 Male

9 (45%)

10 (50%)

11 (55%)

0.819*

 Female

11 (55%)

10 (50%)

9 (45%)

 

Age (years)

45.5 (27–50)

44 (22–50)

42 (25–49)

0.111

Weight (kg)

80 (72–98)2

78.5 (65–98)

74 (55–92)

0.029

Height (cm)

1.65 (1.62–1.80)

1.68 (1.58–1.84)

1.71 (1.6–180)

0.373

WC (cm)

84 (75–100)2

80 (76–101)

77 (65–98)

0.035

BMI (kg/m2)

29.5 (27.1–30.2)2

28 (22.30–30)3

25.5 (21.5–28.3)

 < 0.001

Hemoglobin (g/dl)

11.9 (9.9–14.4)1,2

13.8 (11–16.6)

13.7 (11–15.8)

0.006

Platelets (× 103)

297 (155–433)

285.5 (195–500)

274.5 (195–410)

0.746

WBCs (× 103)

7.41 (4 4–11.2)

6.41 (2.96–10.8)

6.3 (4.24–10.5)

0.113

AST (IU/l)

32.5 (18–44)2

27.5 (10–73)3

18 (11–24)

 < 0.001

ALT (IU/l)

42 (16–65)2

29 (11–94)3

19 (11–25)

 < 0.001

Albumin (mg/dl)

3.55 (2.60–44)1,2

4.40 (3.70–4.7)

4.35 (3.30–4.7)

 < 0.001

Bilirubin (mg/dl)

0.1 (0.22–1.2)

0.99 (0.28–1.48)

0.96 (0.54–1.10)

0.593

INR

1 (0.90–1.20)1,2

1 (0.90–1.10)

1 (0.96–1.0)

0.006

GGT (U/l)

37.5 (20–45)1,2

28 (14–40)3

19.5 (11–30)

 < 0.001

Total cholesterol (mg/dl)

197 (132–286)2

195.5 (128–230)3

135.5 (115–154)

 < 0.001

LDL-C (mg/dl)

161.50 (90–220)1,2

145.5 (67–170)3

80.50 (61–100)

 < 0.001

HDL-C (mg/dl)

44 (24–66)2

51 (33–73)

59.5 (30–90)

0.007

Triglycerides (mg/dl)

163 (63–731)2

146 (60–252)3

86.5 (47–141)

 < 0.001

FBS (mg/dl)

98 (79–104)

92.5 (80–108)

93 (80–100)

0.376

HBA1c

5.5 (5.1–5.7)2

5.35 (4.4–5.7)3

4.65 (4.1–5)

 < 0.001

Serum urea (mg/dl)

5.5 (20–98)1,2

29 (18–45)

26.5 (20–33)

0.001

Creatinine (mg/dl)

1.84 (0.7–3)1,2

0.90 (0.6–1.18)

0.78 (0.58–1.10)

 < 0.001

Uric acid (mg/dl)

6.35 (3.9–8)1,2

5.05 (3.4–8)3

3.30 (3–5)

 < 0.001

Urine RBCs cast

5 (3–10)

3 (3–7)

4 (3–7)

0.076

Urine WBCs cast

6 (3–10)

5 (5–7)

6 (4–10)

0.946

uACR (mg/g)

50.30 (15–113)1,2

16.6 (9.01–29)3

6.85 (2.1–12)

 < 0.001

  1. ALT, alanine aminotransferase; AST, aspartate aminotransferase; FBS, fasting blood sugar; HBA1c, glycated hemoglobin; urine RBCs cast, urine red blood cells cast; urine WBCs cast, urine white blood cells cast; uACR, urinary albumin creatinine ratio. *Chi-square test. 1P-value for comparing groups 1 and 2. 2P-value for comparing groups 1 and 3. 3P-value for comparing groups II and III. P statistically significant at P ≤ 0.05. Group I, patients with NAFLD with CKD, patients with NAFLD without CKD, group III, control