Table 1 Baseline characteristics of patients and controls

Sex

 Male

20 (66.7%)

23 (57.5%)

10 (50%)

χ² = 1.434

0.488

 Female

10 (33.3%)

17 (42.5%)

10 (50%)

Age (years)

58.50 ± 8.44

59.15 ± 9.18

54.05 ± 8.11

F = 2.430

0.094

RBCs (10⁶/ul)

4.16 ± 0.50

3.31 ± 0.66

4.72 ± 0.54

F = 42.80^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.004^*, p₃ < 0.001^*

WBCs (10³/ul)

4.77 ± 1.91

4.38 ± 1.53

5.93 ± 1.29

F = 6.123^*

0.003^*

 Sig. bet. grps

p₁ = 0.586, p₂ = 0.040^*, p₃ = 0.002^*

Platelets (10³/ul)

118.5 ± 30.91

97.40 ± 34.40

293.15 ± 54.90

F = 182.44^*

 < 0.001^*

 Sig. bet. grps

p₁ = 0.069, p₂ < 0.001^*, p₃ < 0.001^*

AST (U/L)

29 (14–50)

45 (22–186)

20.5 (14–32)

H = 54.26^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.011^*, p₃ < 0.001^*

ALT (U/L)

25 (11–38)

31 (14–115)

23.5 (19–30)

H = 21.39^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.496, p₃ < 0.001^*

S. Albumin (g/dl)

3.85 (3.5–4.9)

2.6 (2.1–3.4)

4.2 (3.6–5.0)

H = 68.546^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.131, p₃ < 0.001^*

T. bilirubin (mg/dl)

0.8 (0.2–1.3)

2.4 (0.7–14.1)

0.9 (0.50–1.10)

H = 57.66^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.600, p₃ < 0.001^*

INR

1.10 (0.95–1.29)

1.56 (1.12–2.60)

1.0 (0.90–1.18)

H = 68.02^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.066, p₃ < 0.001^*

Serum urea (mg/dl)

29 (10–53)

42.5 (9–139)

31.5 (24–44)

H = 10.561^*

0.005^*

 Sig. bet. grps

p₁ = 0.002^*, p₂ = 0.460, p₃ = 0.047^*

S. creatinine (mg/dl)

0.85 (0.5–1.4)

1.3 (0.6–3.8)

0.9 (0.7–1.3)

H = 19.090^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.524, p₃ = 0.003^*

CRP

6.60 (1.30–15.0)

38.90 (6.0–80.0)

4.45 (2.60–6.10)

H = 65.104^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001*, p₂ = 0.006*, p₃ < 0.001*

MELD-NA

10.0 (7.0–14.0)

22.0 (10.0–33.0)

8.0 (6.0–11.0)

Η = 66.551^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001*, p₂ = 0.042*, p₃ < 0.001*

FIB-4

2.82 (2.59–3.26)

5.72 (2.19–20.40)

0.74 (0.48–1.22)

Η = 60.737^*

 < 0.001^*

 Sig. bet. Grps

p₁ < 0.001*, p₂ < 0.001*, p₃ < 0.001*

Resistin level (pg/ml)

259.5 (110–410)

638 (236–923)

62 (45–81)

H = 70.53^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.001^*, p₃ < 0.001^*

IL-6 level (pg/ml)

27 (11–45)

53.5 (17–131)

7.2 (4.9–10.2)

H = 65.96^*

 < 0.001^*

 Sig. bet. grps

p₁ < 0.001^*, p₂ = 0.001^*, p₃ < 0.001^*