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Table 4 Comparison of variables in HCV-related cirrhotic patients with and without sarcopenia

From: Evaluation of handgrip strength as a predictor of sarcopenia in patients with HCV-related cirrhosis

  

Cirrhosis group (n = 32)

p-value

  

Non-sarcopenic (n = 21)

Sarcopenic (n = 11)

Variable

 

n

%

n

%

Sex

F

6

28.6%

4

36.4%

0.703

M

15

71.4%

7

63.6%

Child class

Child A

14

66.7%

2

18.2%

0.009

Child C

7

33.3%

9

81.8%

CRP

Negative

17

81.0%

8

72.7%

0.667

Positive

4

19.0%

3

27.3%

DEXA-BMD scan

Normal

2

9.5%

0

0.0%

0.326

Osteopenia

12

57.1%

6

54.5%

Osteoporosis

7

33.3%

5

45.5%

Age (years)

55.8

12.5

63.8

4.2

0.048

MELD score

9

4

10

6

0.630

BMI (kg/m2)

25.0

4.8

26.4

3.7

0.426

MAMC (cm)

26.2

2.5

25.9

3.2

0.715

MAC (cm)

23.1

2.4

22.0

2.6

0.213

WC (cm)

92

16

100

10

0.116

HC (cm)

90.9

14.5

96.4

8.3

0.257

WHR

1.01

0.10

1.03

0.06

0.535

Haemoglobin (g/dl)

12.3

1.9

11.8

2.5

0.520

WBC (k/mm3)

6.0

2.0

7.8

4.8

0.258

Platelets (k/mm3)

150

68

158

76

0.752

Total protein (g/dl)

6.7

0.6

6.7

0.4

0.927

Serum albumin (g/dl)

3.83

0.74

3.54

0.52

0.257

AST (IU/l)

27.6

10.2

41.1

21.6

0.072

ALT (IU/l)

26

11

34

17

0.153

Total bilirubin (mg/dl)

0.69

0.30

0.98

0.67

0.098

Conjugated bilirubin (mg/dl)

0.24

0.11

0.35

0.22

0.155

PT (s)

12.84

0.90

13.27

1.41

0.300

PC (%)

89.9

9.9

87.5

12.9

0.550

INR

1.10

0.10

1.11

0.15

0.713

Serum creatinine (mg/dl)

1.09

0.36

1.17

0.43

0.609

Serum urea (mg/dl)

29.7

8.1

34.2

12.3

0.221

Serum Na+ (mmol/l)

135.6

5.1

135.1

4.5

0.794

Serum K+ (mmol/l)

4.01

0.67

4.54

0.81

0.056

Handgrip strength (kg)

33.7

10.0

19.7

5.8

 < 0.001

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, CRP C-reactive protein, DEXA-BMD dual-energy X-ray absorptiometry bone mineral density, HC hip circumference, INR international normalised ratio, MAC mid-arm circumference, MAMC mid-arm muscle circumference, WBC white blood cells, WC waist circumference, WHR waist-hip ratio, PC prothrombin concentration, PT prothrombin time