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Table 1 Demographic data and laboratory investigations in the studied patients in relation to SVR to DAAs

From: Outcome of direct-acting antiviral treatment in patients with hepatitis C virus/hepatitis B virus coinfection

SVR (N = 191)

No SVR (N = 9)

P value

Age (years)

Mean ± SD

45.14 ± 7.32

55.44 ± 4.53

 < 0.001

Min–Max

24–63

48–61

Sex

Male

106

55.5%

9

100%

0.011

Female

85

44.5%

0

0%

Laboratory investigations

Mean ± SD

Min–Max

 

FBS (mg/dL)

93.94 ± 24.52

125.33 ± 30.44

 < 0.001

Hb (g/dL)

13.03 ± 1.11

13.18 ± 0.91

0.69

WBC (× 103)

6.52 ± 1.04

6.34 ± 0.85

0.62

PLT (× 103)

182.58 ± 56.84

101.89 ± 39.79

 < 0.001

ALT (U/L)

36.11 ± 11.8

34 ± 11.17

0.59

AST (U/L)

39.71 ± 17.92

42 ± 17.5

0.74

Albumin (g/dL)

3.89 ± 0.22

3.64 ± 0.17

0.001

Creatinine (mg/dL)

0.74 ± 0.09

0.83 ± 0.07

0.006

INR

1.11 ± 0.1

1.1 ± 0.09

0.64

PC (%)

92.19 ± 7.77

92.89 ± 5.25

0.79

Total bilirubin (mg/dL)

0.55 ± 0.25

0.56 ± 0.22

0.74

Direct bilirubin (mg/dL)

0.18 ± 0.03

0.18 ± 0.02

0.75

AFP (ng/mL)

4.66 ± 1.71

4.65 ± 1.67

0.97

Liver stiffness (kPa)

7.77 ± 2.54

12.65 ± 4.43

 < 0.001

HCV RNA level (IU/mL)

1.05 \(\times\) 105 ± 2.28 \(\times\) 105

2.43 \(\times\) 105 ± 1.87 \(\times\) 105

0.075

  1. Statistical test used: sample T test and Fisher’s exact test
  2. SD Standard deviation, SVR Sustained virological response, DAAs Direct-acting antivirals, N Number, FBS Fasting blood sugar, Hb Hemoglobin, WBCs White blood cells, ALT Alanine aminotransferase, AST Aspartate aminotransferase, INR International normalization ratio, PC Prothrombin concentration, AFP Alpha-fetoprotein, RNA Ribonucleic acid, kPa Kilopascal
  3. P value < 0.05 is considered statistically significant (95% confidence interval)