Table 4 Comparison between biochemical profile of naïve and relapse groups before and after treatment

Total leucocytic count (X 10^9c /L)

 Range

4.3–10

5–8.9

0.867

0.397

4.5–10

4.9–8.9

1.000

0.330

 Mean ± SD

7.050 ± 1.558

6.755 ± 0.966

7.015 ± 1.629

6.600 ± 0.956

Hemoglobin (g/dl)

 Range

11–17.9

13–16.5

-0.441

0.664

12.1–16

12.7–16

−2.039

0.056

 Mean ± SD

14.500 ± 1.540

14.600 ± 0.901

14.02 ± 1.108

14.675 ± 0.846

Platelet (X 10^9c /L)

 Range

109–321

100–317

-5.266

 < 0.001*

87–230

95–287

−6.654

<0.001*

 Mean ± SD

166.350 ± 53.524

216.050 ± 53.331

135.25 ± 37.022

206.65 ± 49.290

Prothrombin time

 Range

11.5–14

11–12.9

3.575

0.002*

11–13

10–13.6

−1.491

0.152

 Mean ± SD

12.590 ± 0.713

11.925 ± 0.495

11.943 ± 0.595

12.28 ± 0.861

AST (U/L)

 Range

16–89

11–24

6.725

 < 0.001*

23–88

11–29

7.185

<0.001*

 Mean ± SD

46.550 ± 17.707

19.550 ± 3.692

47.2 ± 17.374

19.5 ± 3.791

ALT (U/L)

 Range

22–62

17–33

5.506

 < 0.001*

25–77

17–42

6.462

<0.001*

 Mean ± SD

38.300 ± 12.520

24.400 ± 4.593

45.600 ± 15.250

25.85 ± 5.976

Total bilirubin (mg/dl)

 Range

0.5–1.4

0.5–1.1

0.914

0.372

0.4–1.7

0.5–1.9

−1.287

0.214

 Mean ± SD

0.930 ± 0.236

0.874 ± 0.172

0.956 ± 0.329

1.035 ± 0.283

Albumin (g/dl)

 Range

3.7–4.5

4–4.7

-2.008

0.059

3.6–4.4

3.7–4.7

−2.101

0.049*

 Mean ± SD

4.030 ± 0.232

4.170 ± 0.200

4.010 ± 0.210

4.150 ± 0.240

RBP4 (ng/ml)

 Range

45 –73

37–65

17.528

 < 0.001*

29–49

21–47

10.957

<0.001*

 Mean ± SD

59.025 ± 8.012

49.875 ± 7.323

39.450 ± 6.134

34.075± 6.697

Creatinine mg/dl

 Range

0.34–1.36

0.6–1.1

0.370

0.713

0.57–1.2

0.7–1.1

0.542

0.590

 Mean ± SD

0.98 ± 0.25

0.853 ± 0.130

0.92 ± 0.19

0.891 ± 0.100