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Table 2 Relationship between prolactin and the frequency of studied T regulatory cell subtypes and tumor clinic-pathological status in hepatocellular carcinoma patients

From: Interaction of peripheral CD4+CD25+CD127 Tregs with prolactin in HCV hepatocellular carcinoma: oncogenic or immunogenic mechanisms

  

Prolactin

CD4+CD25+ Tregs

CD4+CD25+CD127Tregs

mTGFβ1/

CD4+CD25+Tregs

mTGFβ1/

CD4+CD25+CD127Tregs

Size of nodule(s)

 < 5 cm

15 (12 − 60)

3.3 (1.7 − 6.3)

67 (52.3 − 82.1) (1)

23 (13.7 − 38.8)

16.3 (7.2 − 25.9)

 ≥ 5 cm

15 (12 − 38)

5.8 (1.1 − 13.2)

59 (32 − 77.5)

31.8 (14.4 − 59.6)

15.2 (3.5 − 36.7)

 

P-value

0.88

0.34

0.30

0.24

0.93

Number of nodule(s)

Solitary

12 (10 − 27)

3.4 (1 − 9.3) (1)

66.4 (35.8 − 83.9)

26.5 (12.1 − 64)

20 (6.1 − 32.7)

Multiple

28 (15 − 50)

5.1 (1.1 − 9.4)

63.2 (33.3 − 75)

30 (19 − 43.7)

14 (4.7 − 25)

 

P-value

0.02

0.84

0.68

0.88

0.42

Portal vein thrombosis

Present

15 (12 − 52)

5.8 (1.8 − 9.6)

67.2 (44.2 − 84.7)

27.8 (13.6 − 54)

12.2 (5.3 − 25.9)

Absent

15 (12 − 34)

2.7 (0.83 − 7.7)

57.2 (30.5 − 75.6)

29.9 (14.6 − 57)

19 (7.6 − 33.3)

 

P-value

0.94

0.17

0.17

0.67

0.30

  1. The data are expresses as median and 25–75% interquartile and compared by the Mann–Whitney test