Table 1 Demographic, laboratory, and flow cytometric data of the studied groups

Age (years)

54 (51.5–59.2)

55 (50–58)

55 (49–59)

0.86

Male gender (%)

36 (75%)

32 (66.7%)

30 (62.5%)

0.88

Hemoglobin% (gm/dl)

10 (9.1–11.3) ***

10.3 (8.9–10.9) ***

14.5 (12.7–15.2)

 < 0.001

White blood cells count (× 103

6.8 (5.2–9.2)

6.5 (4.1–8.4)

6.6 (5.6–8.2)

0.28

Platelet count (× 103)

107 (93–147) ***

103 (55–137) ***

258 (205–305)

 < 0.001

Alanine aminotransferase (U/l)

47 (25–62)

32 (25–51) **

21 (14.5–33)

 < 0.001

Aspartate aminotransferase( U/l)

67 (37–89)

61 (37–77) ***

23 (17–34)

 < 0.001

Albumin (gm/dl)

2.7 (2.3–2.9) ‡***

2.4 (2.1–2.8) ***

4.2 (3.8–4.5)

 < 0.001

Bilirubin (mg/dl)

1.9 (1.1–3.8) **

2.5 (1.4–4.8) ***

0.70 (0.40–0.90)

 < 0.001

International normalized ratio

1.6 (1.3–1.8) ‡‡ ***

1.8 (1.5–2.3) ***

1 (1–1.1)

 < 0.001

Creatinine (mg/dl)

0.97 (0.7–1.3)

0.95 (0.8–1.2) *

0.90 (0.8–1.05)

0.83

Child class A/B/C( n)

6/18/24

2/16/30

–––

Serum Prolactin (ng/ml)

20 (12–50) ***

25 (12–45)**

10 (5.1–30.9)

 < 0.001

Frequency of CD4 + CD25 + Tregs (%)

4.5 (1.2–9.4)

4.91 (2.1–13.5)

6.8 (1.6–8.4)

0.47

Frequency of D4 + CD25 + CD127-Tregs (%)

64.9 (34.6–80.7)

67.6 (43.3–81.3)

71.4 (57.8–84.4)

0.29

Frequency of TGFβ1/CD4 + CD25 + 

Tregs (%)

28.3 (15.2–54.4) ***

25 (9.6–57.7) ***

10 (5.1–30.9)

 < 0.001

Frequency of mTGFβ1/CD4 + CD25 + CD127- Tregs (%)

15.5 (6–30.9) ***

20 (8.9–35.4)***

4.9 (1.9–12.2)

 < 0.001