Table 3 Comparison between the two cholestatic groups (biliary atresia and non-biliary) and control regarding primary and secondary bile acids in conjugated and unconjugated forms in serum and urine

Serum

 Min.–Max.

0.01–0.39

0.0–2.21

0.0–1.20

6.671^*

<0.036^*

 Mean ± SD.

0.09 ± 0.15

0.28 ± 0.41

0.28^a ± 0.21

 Median (IQR)

0.16 (0.01–0.13)

0.13 (0.02–0.34)

0.25 (0.15–0.30)

 Min.–Max.

31.60–418.70

0.35–495.0

0.33–10.43

135.435^*

<0.001^*

 Mean ± SD.

182.02 ± 103.32

127.93 ± 109.95

3.03^ab ± 2.29

 Median (IQR)

146.0 (97.56–141.85)

97.90 (51.40–160.7)

2.85 (1.09–4.0)

 Min. – Max.

0.0–0.51

0.0–1.80

0.0–0.60

0.732

0.694

 Mean ± SD.

0.19 ± 0.20

0.20 ± 0.32

0.18 ± 0.13

 Median (IQR)

0.12 (0.01–0.30)

0. 2 (0.01–0.35)

0.14 (0.09–0.24)

 Min.–Max.

0. 33–6.14

0.05–16.23

0.19–3.03

94.794^*

<0.001^*

 Mean ± SD.

2.69 ± 1.7

4.13^a ± 3.26

0.80^ab ± 0.66

 Median (IQR)

2.16 (0.4–2.98)

3. 13 (0.05–4.43)

0.49 (0.19–0.55)

Urinary

 Min.–Max.

0.0–0.21

0.0–0.81

0.0–1.03

0.976

0.614

 Mean ± SD.

0.04 ± 0.06

0.07 ± 0.17

0.07 ± 0.17

 Median (IQR)

0.0 (0.0–0.04)

0.0 (0.0–0.06)

0.01 (0.0–0.04)

 Min.–Max.

1.81–188.0

0.02–137.0

0.0–6.90

123.127^*

<0.001^*

 Mean ± SD.

51.44 ± 49.69

29.27 ± 29.92

1.20^ab ± 1.54

 Median (IQR)

37.40 (12.70–76.80)

20.02 (6.26–43.0)

0.53 (0.10–2.20)

 Min.–Max.

0.0–0.19

0.0–0.34

0.0–0.36

0.289

0.865

 Mean ± SD.

0.03 ± 0.06

0.06 ± 0.09

0.04 ± 0.08

 Median (IQR)

0.0 (0.0–0.04)

0.0 (0.0–0.10)

0.01 (0.0–0.03)

 Min.–Max.

0.0–2.35

0.0–8.77

0.0–1.02

55.367^*

<0.001^*

 Mean ± SD.

0.63 ± 0.58

1.14 ± 1.44 ^a

0.14^ab ± 0.21

 Median (IQR)

0.4 (0. 0–0.95)

0.65 (0.01–1.39)

0.02 (0.0–0.24)