Table 1 Laboratory and diagnostic workflow for differential diagnosis between biliary atresia and non-biliary atresia patients
From: The value of blood and urine metabolomics in differential diagnosis of cholestasis in infants
Work-up test | Biliary atresia | Non-biliary atresia | P Value | ||
|---|---|---|---|---|---|
Acholic stool (%) | 36/37 | 97.3% | 32/65 | 35.4% | <0.001* |
Total bilirubin (mg/dL) | 10.59 ± 5.64 | 11.27 ± 6.33 | 0.549 | ||
Direct bilirubin (mg/dL) | 7.79 ± 4.72 | 7.85 ± 4.54 | 0.661 | ||
GGT (IU/L) | 938.14± 635.60 | 426.26 ± 603.97 | <0.001* | ||
Serum total bile acids (μMol/L) | 132.08 ± 75.26 | 109.32 ± 70.69 | 0.158 | ||
CMV IgM | |||||
 Positive | 15 | 40.5% | 16 | 24.6% | 0.093 |
 Negative | 22 | 59.5% | 49 | 75.4% |  |
CMV IgG | |||||
 Positive | 30 | 81.1% | 52 | 80% | 0.895 |
 Negative | 7 | 18.9% | 13 | 20% |  |
Ultrasound (%) | |||||
Small, contracted, or non-visualized gallbladder (%) | 36/37 | 97.3% | 22/65 | 31.9% | <0.001* |
Liver biopsy (%) | 37/37 | 100% | 32/65 | 49.23 % | Â |
Intraoperative cholangiogram (%) | 37/37 | 100% | 2/65 | 3.076% | <0.001* |