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Table 1 General clinical features of enrolled patients

From: Liver resection of hepatocellular carcinoma in HIV-HCV co-infected patients: a retrospective case series

 

HIV+/HCV+

HIV−/HCV+

p-value

Patients, n

5

11

 

Sex, n (%)

 Male

5 (100)

8 (72.73)

0.509

 Female

0

3 (27.27)

Age (years)

 Mean ± SD (min; max)

53.2 ± 4.66 (49; 60)

62.54 ± 10.27 (48; 79)

0.076

 Median (25°; 75°)

51 (50; 56)

62 (64; 70.5)

 

ECOG PS, n (%)

 0

5 (100)

8 (72.72)

0.509

 1

0 (0)

3 (27.27)

Comorbidities, n (%)

 Diabetes

1 (20)

1 (9.09)

0.99

 Heart failure

0

1 (9.09)

0.99

 Chronic kidney disease

0

0

1

 Respiratory insufficiency

0

3 (27.27)

0.509

 Previous abdominal surgery

2 (40)

7 (63.63)

0.596

Charlson comorbidity index

 Mean ± SD (min; max)

4.8 ± 1.09 (4; 6)

5.36 ± 1.36 (3; 8)

0.447

 Median (25°; 75°, %)

4 (4; 6)

5 (5; 6)

 

 < 7

6 (100)

9 (81.81)

0.515

 ≥ 7

0

2 (18.18)

ASA score, n (%)

 1

0

1 (9.09)

0.99

 2

4 (80)

8 (72.72)

 3

1 (20)

2 (18.18)

Cirrhosis, n (%)

4 (80)

9 (81.81)

0.99

Child-Pugh class, n (%)

 A

4 (80)

11 (100)

 

 B

1 (20)

0

0.315

 C

0

0

 

MELD

 Mean ± SD (min; max)

9 ± 2.82 (6; 12)

9.18 ± 2.4 (7; 14)

0.895

 Median (25°; 75°, %)

8 (7; 12)

8 (8; 10)

 

AFP ng/mL, n (%)

 ≤ 20

4 (100)

4 (40)

0.085

 > 20

0

6 (60)

 

HCV treatment response, n (%)

 SVR

4 (80)

10 (90.9)

0.99

 Non-SVR

1 (20)

1 (9.09)

 

Number of nodules at imaging, n

5

15

 

 Mean (range)

1 (1; 1)

1.36 (1; 3)

0.244

Largest nodule diameter at imaging (mm)

 Mean ± SD

26.4 ± 14.2

29.3 ± 11

0.57

Portal vein thrombosis, n (%)

0

1 (9.09)

0.99

BCLC stage, n (%)

 0-A

5 (100)

9 (81.81)

0.99

 B-C

0

2 (18.18)

 

Milan criteria, n (%)

 Out

0 (0)

2 (18.18)

0.99

 In

5 (100)

9 (81.81)

 
  1. SD standard deviation; ECOG PS Eastern Cooperative Oncology Group Performance Status, ASA American Society of Anesthesiologist classification, MELD model for end-stage liver disease, AFP alpha-fetoprotein, SVR sustained virologic response, BCLC Barcelona Clinic Liver Cancer