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Table 3 Treatment decision, duration, and outcome in both HCV patients post chemotherapy (cases) and HCV patients without cancer (controls)

From: Efficacy and safety of direct-acting antivirals for HCV in patients with extrahepatic malignancies: real-life experience

 

Groups of HCV patients

Total

N (%)

171

p-value

Post chemotherapy

N (%)

83

Without cancer

N (%)

88

Treatment decision

IFN/SOF/RBV

12 (14.5%)

5 (5.7%)

17 (9.9%)

 

PAR/OMP/RBV

1 (1.2%)

1 (1.1%)

2 (1.2%)

 

SOF/DAC

18 (21.7%)

44 (50%)

62 (36.3%)

 

SOF/DAC/RBV

16 (19.3%)

20 (22.7%)

36 (21.1%)

 

SOF/PAR/OMP/RBV

1 (1.2%)

0 (0%)

1 (0.6%)

 

SOF/RBV

23 (27.7%)

18 (20.5%)

41 (24%)

 

SOF/SIM

12 (14.5%)

0 (0%)

12 (7%)

 

Treatment duration

12 weeks

55 (66.3%)

58 (65.9%)

113 (66.1%)

0.961

24 weeks

28 (33.7%)

30 (34.1 %)

58 (33.9%)

 

Treatment outcome

SVR

83 (100%)

86 (97.7%)

169 (98.9%)

0.497

Non SVR

0 (0%)

2 (2.3%)

2 (1.2%)

 

SVR

83 (100%)

86 (97.7%)

169 (98.9%)

0.385

Relapser

0 (0%)

1 (1.1%)

1 (0.6%)

DC

0 (0%)

1 (1.1%)

1 (0.6%)

  1. SOF Sofosbuvir, RBV Ribavirin, INF Interferon, SIM Simeprevir, DAC Daclatasvir, PAR/OMP Paritaprevir/ombitasvir, DC Discontinue