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Table 2 Comparison between the studied groups regarding their histopathology

From: The regenerative effect of stem cells on acetaminophen-induced hepatotoxicity in male albino rats

Histopathology

Normal control

n=10

Pathological control

n=10

SC control

n=10

SC-treated group

n=10

Spontaneous recovery group

n=10

Fisher’s exact test

P value

Centrilobular fibrosis:

 Yes

0 (0%)

10 (100%)

0 (0%)

2 (20%)

6 (60%)

32.15

<0.001

 No

10 (100%)

0 (0%)

10 (100%)

8 (80%)

4 (40%)

  

Portal fibrosis

 Yes

0 (0%)

6 (60%)

0 (0%)

5 (50%)

8 (80%)

22.01

<0.001

 No

10 (100%)

4 (40%)

10 (100%)

5 (50%)

2 (20%)

  

Hemorrhage

 Yes

0 (0%)

10 (100%)

0 (0%)

1 (10%)

8 (80%)

39.21

0.001

 No

10 (100%)

0 (0%)

10 (100%)

9 (90%)

2 (20%)

  

Areas of necrosis

 Yes

0 (0%)

8 (80%)

0 (0%)

0 (0%)

6 (60%)

30.153

<0.001

 No

10 (100%)

2 (20%)

10 (100%)

10 (100%)

4 (40%)

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