Variable
|
n (%)
|
---|
Sex
|
Males
|
177 (71.1)
|
Females
|
72 (28.9)
|
Precipitating factor of ACLF
|
Sepsis
|
124 (49.8)
|
Upper GI bleeding
|
23 (9.2)
|
De novo AIH
|
1 (0.4)
|
AIH flare
|
8 (3.2)
|
DILI
|
9 (3.6)
|
HBV
|
2 (0.8)
|
HCV
|
1 (0.4)
|
HDV
|
2 (0.8)
|
HEV
|
1 (0.4)
|
Wilson’s disease
|
1 (0.4)
|
Unknown
|
77 (30.9)
|
Etiology of pre-existing CLD
|
HCV
|
144 (57.8)
|
Autoimmune hepatitis
|
8 (3.2)
|
Budd-Chiari syndrome
|
2 (0.8)
|
HBV
|
13 (5.2)
|
HBV-HCV co-infection
|
1 (0.4)
|
Unknown
|
81 (32.5)
|
Ascites
|
No
|
76 (30.5)
|
Mild to moderate
|
154 (61.8)
|
Marked
|
19 (7.6)
|
Hepatic encephalopathy
|
No
|
82 (32.9)
|
Grades I–II
|
123 (49.4)
|
Grades III–IV
|
44 (17.7)
|
Initial admission
|
Ward
|
58 (23.3)
|
ICU
|
191 (76.7)
|
Child-Pugh class
|
B
|
18 (7.2)
|
C
|
231 (92.8)
|
ACLF grade
|
1
|
89 (35.7)
|
2
|
109 (43.8)
|
3
|
51 (20.5)
|
Outcome
|
Improved
|
64 (25.7)
|
Deceased
|
185 (74.3)
|
- ACLF Acute-on-chronic liver failure, AIH Autoimmune hepatitis, CLD Chronic liver disease, DILI Drug-induced liver injury, ICU Intensive care unit, GI Gastrointestinal, HBV Hepatitis B virus, HCV Hepatitis C virus, HDV Hepatitis D virus, HEV Hepatitis E virus