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Table 2 Laboratory changes before and after treatment

From: Effect of direct-acting antiviral drugs on portal circulation hemodynamics in cirrhotic patients infected with HCV

Chemical changes Before treatment After treatment P
APRI test Range 0.3–6.3 0.2–2.9 0.001*
Mean ± SD 1.4 ± 1.3 0.79 ± 0.84
Total bilirubin Range 1–2 1–4 0.4
Mean ± SD 1.11 ± 0.36 1.04 ± 0.75
ALT Range 20–94 17–77 0.001*
Mean ± SD 40 ± 23.4 31.5 ± 19.03
AST Range 24–102 20–87 0.001*
Mean ± SD 46.4 ± 26.6 38.6 ± 22.2
Albumin Range 2.8–4.5 3.5–4.9 0.001*
Mean ± SD 3.6 ± 0.47 4.2 ± 0.37
INR Range 1–2 1–2 0.001*
Mean ± SD 1.26 ± 0.29 1.10 ± 0.12
PC Range 42.5–97 50–93 0.001*
Mean ± SD 72.3 ± 19.1 82.9 ± 11.4
Platelet count Range 51–294 86–378 0.001*
Mean ± SD 130.3 ± 55.09 189.5 ± 76.4
FIB4 Range 1.06–9.7 0.84–7.4 0.001*
Mean ± SD 3.7 ± 2.2 2.5 ± 1.7
  1. APRI AST to platelet ratio index test, FIB4 fibrosis 4 score