Table 5 Clinical and biochemical features of the children before and after treatment
From: Etiology and outcome of neonatal cholestasis: an experience in a tertiary center of Bangladesh
Type | Observed clinical characteristic | Mean or proportion (frequency) (before treatment) | Mean or proportion (frequency) (after treatment) | Test statistic | P value |
|---|---|---|---|---|---|
Intrahepatic (n = 35) | Jaundice | 100% (35 ) | 11% (4) | 16.23 | 0.000 |
Dark urine | 54% (19) | 6% (2) | 5.67 | 0.000 | |
Pale stool | 71% (25) | 9% (3) | 7.59 | 0.000 | |
Hepatomegaly | 91% (32) | 14% (5) | 10.71 | 0.000 | |
Total bilirubin (mg/dL) | 12.94 | 1.25 | 37.86 | 0.000 | |
Direct bilirubin (mg/dL) | 3.89 | 0.16 | 25.70 | 0.000 | |
ALT (IU/L) | 459.66 | 34.29 | 35.98 | 0.000 | |
Alk Ph (IU/L) | 323.86 | 316.40 | 0.319 | 0.752 | |
GGT (IU/L) | 203.00 | 51.89 | 13.34 | 0.000 | |
Extrahepatic (n = 2) | Jaundice | 100% (2) | 0% (0) | Inadequate data to conduct test. | |
Dark urine | 100% (2) | 0% (0) | |||
Pale stool | 0% (0) | 0% (0) | |||
Hepatomegaly | 100% (2) | 0% (0) | |||
Total bilirubin (mg/dL) | 6.3 | 1.2 | |||
Direct bilirubin (mg/dL) | 3.3 | 0.05 | |||
ALT (IU/L) | 85 | 95 | |||
Alk Ph (IU/L) | 870 | 229 | |||
GGT (IU/L) | 970 | 121.5 | |||