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Table 5 Clinical and biochemical features of the children before and after treatment

From: Etiology and outcome of neonatal cholestasis: an experience in a tertiary center of Bangladesh

Type Observed clinical characteristic Mean or proportion (frequency) (before treatment) Mean or proportion (frequency) (after treatment) Test statistic P value
Intrahepatic (n = 35) Jaundice 100% (35 ) 11% (4) 16.23 0.000
Dark urine 54% (19) 6% (2) 5.67 0.000
Pale stool 71% (25) 9% (3) 7.59 0.000
Hepatomegaly 91% (32) 14% (5) 10.71 0.000
Total bilirubin (mg/dL) 12.94 1.25 37.86 0.000
Direct bilirubin (mg/dL) 3.89 0.16 25.70 0.000
ALT (IU/L) 459.66 34.29 35.98 0.000
Alk Ph (IU/L) 323.86 316.40 0.319 0.752
GGT (IU/L) 203.00 51.89 13.34 0.000
Extrahepatic (n = 2) Jaundice 100% (2) 0% (0) Inadequate data to conduct test.
Dark urine 100% (2) 0% (0)
Pale stool 0% (0) 0% (0)
Hepatomegaly 100% (2) 0% (0)
Total bilirubin (mg/dL) 6.3 1.2
Direct bilirubin (mg/dL) 3.3 0.05
ALT (IU/L) 85 95
Alk Ph (IU/L) 870 229
GGT (IU/L) 970 121.5