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Table 2 Laboratory data of the studied groups

From: Matrix metalloproteinase-1 as a non-invasive biomarker to assess liver fibrosis in children with chronic liver disease

Variables CLD patients Healthy controls P value
N = 120 N = 60
ALT (IU/L) median (IQR) 50 (45‑101) 10 (9‑11)a < 0.001
AST (IU/L) median (IQR) 72 (56‑95) 11 (10‑11)a < 0.001
PT (s) 14.7 ± 3.7 12.7 ± 1b < 0.001
Albumin (g/L) 3.37 ± 0.4 3.66 ± 0.19b 0.09
Bilirubin total (mg/dL) 4.5 ± 0.8 1.1 ± 0.19b < 0.001
Bilirubin direct (mg/dL) 2.77 ± 0.94 0.66 ± 0.19b < 0.001
MMP-1 ng/ml
Median (IQR)
17.5
16.5‑18.4
67.6a
55‑83
< 0.001
  1. aU Man-Whitney test
  2. bt test, Hb hemoglobin, WBCs white blood cells, PLT platelets, ALT alanine aminotransferase, AST aspartate aminotransferase, PT prothrombin time, MMP-1 matrix metalloproteinases-1