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Table 2 Laboratory data of the studied groups

From: Matrix metalloproteinase-1 as a non-invasive biomarker to assess liver fibrosis in children with chronic liver disease

Variables

CLD patients

Healthy controls

P value

N = 120

N = 60

ALT (IU/L) median (IQR)

50 (45‑101)

10 (9‑11)a

< 0.001

AST (IU/L) median (IQR)

72 (56‑95)

11 (10‑11)a

< 0.001

PT (s)

14.7 ± 3.7

12.7 ± 1b

< 0.001

Albumin (g/L)

3.37 ± 0.4

3.66 ± 0.19b

0.09

Bilirubin total (mg/dL)

4.5 ± 0.8

1.1 ± 0.19b

< 0.001

Bilirubin direct (mg/dL)

2.77 ± 0.94

0.66 ± 0.19b

< 0.001

MMP-1 ng/ml

Median (IQR)

17.5

16.5‑18.4

67.6a

55‑83

< 0.001

  1. aU Man-Whitney test
  2. bt test, Hb hemoglobin, WBCs white blood cells, PLT platelets, ALT alanine aminotransferase, AST aspartate aminotransferase, PT prothrombin time, MMP-1 matrix metalloproteinases-1