Table 1 Baseline characteristics of AIH-I patients (n = 80)
| Â | AIH-1 | |
|---|---|---|
Biochemical characteristics | ||
Aspartate aminotransferase (AST; U/L) | 230 (57 –960) | |
Alanine aminotransferase (ALT; U/L) | 230 (17 –825) | |
Alkaline phosphatase (ALP; U/L) | 200 (55–613) | |
Gamma glutamyl transferase (GGT; U/L) | 68 (22–100) | |
Prothrombin time (PT; sec) | 16.3 (12–28) | |
Activated partial thromboplastin time (aPTT; sec) | 44 (26–55) | |
International normalized ratio (INR) | 1.6 (1–3.4) | |
Serum total bilirubin (μmol/L) | 51.3 (5.13–353.97) | |
Serum direct bilirubin (μmol/L) | 34.2 (1.71 –263.34) | |
Serum albumin (g/L) | 32 (20–44) | |
Serum total proteins (g/L) | 80 (48–100) | |
Serum total immunoglobulin G (IgG; μmol/L)a | 220.15 (60.37–375.32) | |
Histopathological characteristics | ||
Infiltrating inflammatory cells | Eosinophil | 8 (10) |
Lymphocytes | 16 (45) | |
Plasma cells | 66 (82) | |
Hepatocytes and portal tracts changes | Ballooning and degeneration of hepatocytes | 4 (5) |
Rosettes formation | 16 (20) | |
interface hepatitis (piecemeal necrosis and bridging) | 64 (80) | |
Hepatitis activity index (HAI) | 7 (1–15) | |
Degree of fibrosis | 3 (0–5) | |