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Table 1 Baseline characteristics of AIH-I patients (n = 80)

From: Association of the killer immunoglobulin-like receptor genes KIR2DS1 and KIR2DS4 with pediatric autoimmune hepatitis type I in Egypt

  AIH-1
Biochemical characteristics
Aspartate aminotransferase (AST; U/L) 230 (57 –960)
Alanine aminotransferase (ALT; U/L) 230 (17 –825)
Alkaline phosphatase (ALP; U/L) 200 (55–613)
Gamma glutamyl transferase (GGT; U/L) 68 (22–100)
Prothrombin time (PT; sec) 16.3 (12–28)
Activated partial thromboplastin time (aPTT; sec) 44 (26–55)
International normalized ratio (INR) 1.6 (1–3.4)
Serum total bilirubin (μmol/L) 51.3 (5.13–353.97)
Serum direct bilirubin (μmol/L) 34.2 (1.71 –263.34)
Serum albumin (g/L) 32 (20–44)
Serum total proteins (g/L) 80 (48–100)
Serum total immunoglobulin G (IgG; μmol/L)a 220.15 (60.37–375.32)
Histopathological characteristics
Infiltrating inflammatory cells Eosinophil 8 (10)
Lymphocytes 16 (45)
Plasma cells 66 (82)
Hepatocytes and portal tracts changes Ballooning and degeneration of hepatocytes 4 (5)
Rosettes formation 16 (20)
interface hepatitis (piecemeal necrosis and bridging) 64 (80)
Hepatitis activity index (HAI) 7 (1–15)
Degree of fibrosis 3 (0–5)
  1. Data are given either median (range) or number (%)
  2. aNormal value for serum total IgG 53.37–120.08 μmol/L