Skip to main content

Table 3 Laboratory and fibrosis score changes in early and advanced groups

From: Evaluation of long-term changes of aspartate—platelet ratio index, FIB4, and liver stiffness in chronic hepatitis C patients successfully treated by direct-acting antivirals

 

Early stage

Advanced stage

Baseline

Follow-up

P value

Baseline

Follow-up

P value

Stiffness

5.9±1.5

5.4±2.2

0.04

18±8.8

15.9 ±7.8

0.077

APRI score

0.42±0.3

0.24±0.1

<0.01

0.85±0.5

0.4±0.2

<0.001

Fib4

1±0.6

0.93±0.5

0.1

2.9±2.3

1.8±1.4

0.002

ALT (IU/L)

53±42

21±10

<0.01

55±37

26±11

<0.001

AST (IU/L)

42±30

24±10

<0.01

58±26

28±11

<0.001

AFP (IU/L)

3.3±2

3.5±1.8

0.5

6±4.2

5.5±3

0.4

Albumin (g/dL)

4.2±0.35

4.1±0.3

0.35

3.9±0.6

3.9±0.4

0.5

Total bilirubin (mg/dL)

0.6±0.2

0.7±0.2

0.2

0.9±0.5

0.86±0.3

0.4

Indirect bilirubin (mg/dL)

0.4±0.4

0.4±0.2

0.7

0.6±0.3

0.5±0.2

0.5

WBCx103/mm3

7±2.4

6.8±1.7

0.3

7.1±1.8

6.7±2.1

0.2

Hb

13.8± 1.6

12.5±1.2

<0.001

13±1.9

12.4±1.5

0.008

plateletsx103/mm3

251.5 ± 58

265 ± 72

0.05

199±80

215±67

0.08

INR

1±0.09

1 ±0.09

0.3

1.12.

1.16

0.1

Creatinine

0.87±0.2

0.85±0.15

0.6

0.8±0.1

0.9±0.1

0.8